Road closures near the downtown Mayo Clinic campus

    Construction may affect your arrival. Patients are encouraged to view routing information for how to navigate closures near the downtown campus.

    Please allow extra time for arrival and departure as traffic congestion may occur.

    Map of construction work at Mayo Clinic Rochester

    Expected reopenings:

    1. Second Street Southwest: Fall 2026
    2. West Center Street: 2027
    3. Sixth Avenue: Completed in phases through summer 2027
    4. Fourth Avenue Southwest: Permanently closed for redevelopment
    5. First Street Southwest: Permanently closed for redevelopment
    6. First Street Northwest: Late summer 2026
    7. Fifth Avenue Northwest: Fall 2026
    8. Third Street Northwest: Completed in phases through fall 2026

    Make sure to view the routing information within 24 hours of your appointment for the most up-to-date arrival guidance.

    For details on other road closures across Rochester, visit the City of Rochester’s Downtown Rochester Construction Webpage.