Sickle Cell Disease

Your Result

People with your test result usually have sickle cell disease. https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/16/no.png No genetic variants found https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/03/carrier.png Carrier, no signs https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/15/likely-select.png Likely shows signs of sickle cell disease

Here's What You Need to Know

This test found one Hb S and one Hb C genetic variant in the HBB gene. People with your test result usually have a milder sickle cell disease than people with two Hb S genetic variants. View the variants we test. https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/09/06/18/14/autosomal_recessive-hbsc.png Each of your children will inherit a HBB variant from you. If your partner is not a carrier: each of your children has a 50 percent (1 in 2) chance of inheriting Hb S and a 50 percent (1 in 2) chance of inheriting Hb C. https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/09/06/18/14/autosomal_recessive-hbschemosickle.png If you partner is a carrier of Hb C trait, each of your children has a 25 percent (1 in 4) chance of being a carrier for Hb S, a 25 percent (1 in 4) chance of being a carrier for Hb C, a 25 percent (1 in 4) chance of being affected with hemoglobin C disease, and a 25 percent (1 in 4) chance of being affected with sickle cell disease. https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/09/06/18/14/autosomal_recessive-hbscsickle.png If your partner is a carrier of Hb S trait, each of your children has a 25 percent (1 in 4) chance of being a carrier of Hb S, a 25 percent (1 in 4) chance of being a carrier of Hb C, and a 50 percent (1 in 2) chance of being affected with sickle cell disease.

Here's what you can do

Based on your test results, it is with important to follow up with your health care provider. How do I talk to my healthcare provider? Contact a genetic nurse at the Mayo Clinic. Here's how.

Message a Genetic Nurse

Learn more

About sickle cell disease About the sickle cell disease test