By Mayo Clinic Staff

Dietitian's tip:

Stuffed artichokes make an appealing and substantial side dish. The simple but flavorful stuffing complements the artichokes' nuttiness without overpowering them.

Number of servings

Serves 8


  1. 2 cups fresh breadcrumbs, preferably whole wheat (whole meal)
  2. 1 tablespoon olive oil
  3. 4 large artichokes
  4. 2 lemons, halved
  5. 1/3 cup grated Parmesan cheese
  6. 3 garlic cloves, finely chopped
  7. 2 tablespoons finely chopped fresh flat-leaf (Italian) parsley
  8. 1 tablespoon grated lemon zest
  9. 1/4 teaspoon freshly ground black pepper
  10. 1 cup plus 2 to 4 tablespoons vegetable stock, chicken stock or broth
  11. 1 cup dry white wine
  12. 1 tablespoon minced shallot
  13. 1 teaspoon chopped fresh oregano


Preheat the oven to 400 F. In a bowl, combine the breadcrumbs and olive oil. Toss to coat. Spread the crumbs in a shallow baking pan and bake, stirring once halfway through, until the crumbs are lightly golden, about 10 minutes. Set aside to cool.

Working with 1 artichoke at a time, snap off any tough outer leaves and trim the stem flush with the base. Cut off the top third of the leaves with a serrated knife, and trim off any remaining thorns with scissors. Rub the cut edges with a lemon half to prevent discoloration. Separate the inner leaves and pull out the small leaves from the center. Using a melon baller or spoon, scoop out the fuzzy choke, then squeeze some lemon juice into the cavity. Trim the remaining artichokes in the same manner.

In a large bowl, toss the breadcrumbs with the Parmesan, garlic, parsley, lemon zest and pepper. Add the 2 to 4 tablespoons stock, 1 tablespoon at a time, using just enough for the stuffing to begin to stick together in small clumps.

Using 2/3 of the stuffing, mound it slightly in the center of the artichokes. Then, starting at the bottom, spread the leaves open and spoon a rounded teaspoon of stuffing near the base of each leaf. (The artichokes can be prepared to this point several hours ahead and kept refrigerated.)

In a Dutch oven with a tightfitting lid, combine the 1 cup stock, wine, shallot and oregano. Bring to a boil, then reduce the heat to low. Arrange the artichokes, stem end down, in the liquid in a single layer. Cover and simmer until the outer leaves are tender, about 45 minutes (add water if necessary). Transfer the artichokes to a rack and let cool slightly. Cut each artichoke into quarters and serve warm.

Nutritional analysis per serving

  • Total carbohydrate 20 g
  • Dietary fiber 4 g
  • Sodium 246 mg
  • Saturated fat 1 g
  • Total fat 4 g
  • Cholesterol 5 mg
  • Protein 6 g
  • Monounsaturated fat 2 g
  • Calories 140

This recipe is one of 150 recipes collected in "The New Mayo Clinic Cookbook," published by Mayo Clinic Health Information and Oxmoor House, and winner of the 2005 James Beard award.

April 03, 2012