Channa R. Jayasekera, M.D.

Channa R. Jayasekera, M.D., is a gastroenterologist and transplant hepatologist at Mayo Clinic in Phoenix, Arizona. He specializes in general and transplant hepatology, with expertise in liver cancer, biliary tract and autoimmune liver diseases, alcohol-associated liver disease, and improving outcomes for patients before and after liver transplantation.

Dr. Jayasekera cares for patients with cirrhosis and its complications, hepatocellular carcinoma, cholangiocarcinoma, liver masses, primary sclerosing cholangitis, primary biliary cholangitis, autoimmune hepatitis, viral hepatitis, alcohol and metabolic dysfunction-associated liver disease, and other complex liver conditions. He also evaluates and manages patients with liver tumors, liver masses, and advanced liver disease requiring transplant consideration.

As a member of Mayo Clinic's Liver Transplant Program, Hepatobiliary Clinic, and the Early-Onset and Hereditary GI Cancers Program, the Liver Mass Clinic, and Transplant Oncology Clinic, Dr. Jayasekera collaborates with specialists across hepatology, oncology, transplantation and hepatobiliary surgery, and digestive diseases to develop individualized treatment plans.

Dr. Jayasekera is board-certified in gastroenterology and transplant hepatology by the American Board of Internal Medicine. He received his medical training at Duke University, Stanford University, and California Pacific Medical Center. He performs colonoscopy and upper endoscopy and has received recognition for excellence in teaching and research.

In addition to his clinical practice, Dr. Jayasekera conducts research focused on liver malignancies, biliary tract disease, alcohol-associated liver disease, improving liver transplant outcomes, and expanding access to liver transplantation. Dr. Jayasekera is a member of the Mayo Clinic Research Operations Management Team, the American Association for Study of Liver Diseases, the European Association for Study of the Liver, American Society for Transplantation, the International PSC Study Group, among others.