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Brad S. Hoppe, M.D., M.P.H.

  1. Radiation Oncologist

Dr. Bradford S. Hoppe is a radiation oncologist and Professor of Radiation Oncology at Mayo Clinic in Jacksonville, Florida, where he serves as Medical Director of Particle Therapy. He specializes in advanced radiation therapy for pediatric and adult patients with lymphoma, lung cancer, thymic cancer and other thoracic malignancies. His expertise includes proton therapy, carbon ion (heavy ion) radiation, image-guided radiation therapy (IGRT) and intensity-modulated radiation therapy (IMRT), with a focus on delivering highly targeted treatment while minimizing radiation exposure to healthy tissues.

As an international expert in particle therapy, Dr. Hoppe is advancing the use of proton and heavy ion radiation to improve cancer outcomes and reduce treatment-related side effects. He has a particular interest in integrating precision radiotherapy with immunotherapy and other systemic cancer treatments to provide personalized care for patients with complex cancers.

Dr. Hoppe collaborates closely with medical oncologists, surgeons, radiologists and other specialists through Mayo Clinic's multidisciplinary tumor boards to develop individualized treatment plans for each patient. His research focuses on improving quality of life, reducing radiation-related toxicity and expanding access to innovative therapies through clinical trials.

In addition to caring for patients, he is committed to educating the next generation of radiation oncologists and is recognized internationally for his leadership in particle therapy through lectures, publications and his role as an American Board of Radiology examiner.

"My goal is to provide every patient with the most advanced, personalized treatment available," says Dr. Hoppe. "By combining precision radiation therapy with the latest advances in systemic therapies, including immunotherapy, we can tailor treatment to each patient's cancer while maximizing effectiveness and minimizing side effects."

Outside of medicine, Dr. Hoppe enjoys traveling, cheering on the Jacksonville Jumbo Shrimp and spending time with his family.

  1. 2011
    MPHHarvard School of Public Health
  2. 2008
    Fellowship - Mortimer Lacher Clinical Lymphoma FellowMemorial Sloan Kettering Cancer Center
  3. 2008
    Residency - Radiation OncologyMemorial Sloan Kettering Cancer Center
  4. 2007
    Research Training - Clinical Research Methodology Curriculum Memorial Sloan-Kettering Cancer Center
  5. 2004
    InternshipKaiser Permanente Oakland Medical Center
  6. 2003
    MDCornell University Medical Center
  7. 1998
    BS - BiologyStanford University

Certifications

  1. 2009
    Radiation OncologyAmerican Board of Radiology

Awards and honors

  1. 2026
    America's Most Honored Doctors - 2026American Registry
  2. 2026
    "Top Doctors" 2026Castle Connolly Top Doctors
  3. 2026
    Top Doctor 2026Top Docs, Jacksonville Magazine
  4. 2025
    Above and Beyond Recognition Program
  5. 2025
    "Top Doctors" 2025Castle Connolly Top Doctors
  6. 2025
    Top Doctor 2025Top Docs, Jacksonville Magazine
  7. 2024
    Karl Musshoff Price-- Poster AwardInternational Society Hodgkin Lymphoma (ISHL)
  8. 2024
    America's Most Honored Doctors 2024- Top 10%American Registry
  9. 2024
    2023 Top Performer: Patient experienceMayo Clinic
  10. 2024
    Fellow of American College of Radiology (FACR)American College of Radiology
  11. 2024
    Teacher of the Year AwardMayo Clinic School of Graduate Medical Education
  12. 2024
    "Top Doctors" 2024Castle Connolly Top Doctors
  13. 2024
    Top Doctor 2024Top Docs, Jacksonville Magazine
  14. 2023
    Fellow of ASTRO- FASTROAmerican Society for Radiation Oncology
  15. 2023
    Steven A. Leibel Memorial AwardAmerican Society for Radiation Oncology
  16. 2023
    America's Most Honored Florida DoctorsAmerican Registry
  17. 2023
    "Top Doctors" 2023Castle Connolly Top Doctors
  18. 2023
    Top Doctor 2023Top Docs, Jacksonville Magazine
  19. 2022
    America's Most Honored Doctors- Top 5% 2022American Registry
  20. 2022
    "Top Doctors" 2022Castle Connolly Top Doctors
  21. 2022
    Top Doctor 2022Top Docs, Jacksonville Magazine
  22. 2021
    America's Most Honored Doctors- Top 10% 2021American Registry
  23. 2021
    "Top Doctors" 2021Castle Connolly Top Doctors
  24. 2021
    Top Doctor 2021Top Docs, Jacksonville Magazine
  25. 2020
    America's Most Honored Doctors 2020- Top 10%American Registry
  26. 2020
    "Top Doctors" 2020Castle Connolly Top Doctors
  27. 2019
    America's Most Honored Professionals 2019- Top 5%American Registry
  28. 2019
    "Top Doctors" 2019Castle Connolly Top Doctors
  29. 2018
    America's Most Honored Professionals 2018- Top 5%American Registry
  30. 2018
    Educator of the YearAssociation of Residents in Radiation Oncology
  31. 2018
    University Term ProfessorUniversity of Florida College of Medicine
  32. 2018
    "Top Doctors" 2018Castle Connolly Top Doctors
  33. 2017
    America's Most Honored Professionals 2017--Top 10%American Registry
  34. 2017
    "Top Doctors" 2017Castle Connolly Top Doctors
  35. 2016
    America's Most Honored 2016American Registry
  36. 2016
    "Top Doctors" 2016Castle Connolly Top Doctors
  37. 2015
    "Top Doctors" 2015Castle Connolly Top Doctors
  38. 2014
    Golden DRE Award from Prostate Cancer Survivorship GroupUniversity of Florida
  39. 2013
    Exemplary Teacher AwardUniversity of Florida College of Medicine
  40. 2013
    James E. Lockwood Jr, Professorship in Proton TherapyUniversity of Florida College of Medicine
  41. 2013
    Top Team Effort Award University of Florida Health Proton Therapy Institute
  42. 2013
    Certificate of Excellence in Reviewing International Journal of Radiation Oncology, Biology, Physics
  43. 2008
    RSNA Resident Research AwardMemorial Sloan Kettering Cancer Center
  44. 2008
    Travel GrantAmerican Society for Radiation Oncology
  45. 2007
    Travel GrantAmerican Society for Radiation Oncology
  46. 2007
    Poster - first prize, "Post-operative intensity modulated radiation therapy for cancers of the paranasal sinus, nasal cavity, and lacrimal gland: technique, toxicity, and early outcomes"New York Roentgen Society
  47. 2007
    Poster- ASTRO award, "Preliminary report of the toxicity and outcomes in patients treated with post-operative intensity modulated radiation therapy for cancer of the paranasal sinus, nasal cavity, and lacrimal gland"Multidisciplinary Head and Neck Cancer Symposium
  48. 2003
    Graduated with HonorsCornell University Medical College
  49. 2003
    Gustavo Cudkowicz Memorial Prize in ImmunologyCornell University Medical College
  50. 2003
    The Jay Lawrence Award for Clinical Proficiency in Infectious DiseasesCornell University Medical College
  51. 2002
    Poster – first prize, "Prevalence of atopic disease in a polyhelminthic endemic area"International Health Medical Education Consortium (IHMEC)
  52. 1998
    Graduated with HonorsStanford University

Professional memberships

  1. 2025 - present
    MemberPersonnel Committee, Mayo Clinic Florida Committees
  2. 2019 - 2022
    Journal Club OfficerAmerican College of Radiology
  3. 2019 - present
    ChairRadiation Oncology, Hodgkin Lymphoma Committee, Children’s Oncology Group
  4. 2019 - present
    MemberSteering Committee, International Lymphoma Radiation Oncology Group
  5. 2018 - 2019
    MemberData Integrity & Safety Committee, UF Health Shands Hospital
  6. 2018 - 2019
    MemberTumor Board, Hematologic Program, UF Health Shands Hospital
  7. 2018 - present
    MemberAppropriateness Criteria Expert Panel on Lymphoma, American Radium Society
  8. 2017 - 2019
    Vice Chair of ResearchUF Health Proton Therapy Institute
  9. 2017 - 2019
    ReviewerLymphoma Abstract Review Committee, American Society for Radiation Oncology
  10. 2017 - present
    MemberAmerican Radium Society
  11. 2017 - present
    MemberCME/MOC Committee, American Society for Radiation Oncology
  12. 2017 - present
    MemberHodgkin Lymphoma Steering Committee, Children’s Oncology Group
  13. 2016 - 2019
    WriterLeukemia & Lymphoma Exam Committee, American College of Radiology
  14. 2015 - 2019
    Council MemberInternational Lymphoma Radiation Oncology Group
  15. 2015 - 2019
    ReviewerLung and Sarcoma Abstract Review Committee, Particle Therapy Cooperative Group
  16. 2015 - 2016
    MemberFlorida Society of Clinical Oncology
  17. 2015 - present
    MemberInternational Lymphoma Radiation Oncology Group
  18. 2014 - present
    MememberNRG Oncology
  19. 2013 - 2017
    ChairJournal CME Task Force, Education Committee of the Education Council, American Society for Radiation Oncology
  20. 2013 - 2015
    ReviewerLymphoma Abstract Review Committee, American Society for Radiation Oncology
  21. 2013 - present
    ChairLymphoma Subcommittee, Particle Therapy Cooperative Group
  22. 2013 - present
    MemberLung Subcommittee, Particle Therapy Cooperative Group
  23. 2013 - present
    MemberParticle Therapy Cooperative Group - North America (PTCOG-NA)
  24. 2012 - 2019
    MemberBoard of Directors, Proton Collaborative Group
  25. 2012 - 2018
    ChairHodgkin Disease Committee, Proton Collaborative Group
  26. 2012 - 2017
    MemberEducation Committee of the Education Council, American Society for Radiation Oncology
  27. 2012 - present
    MemberParticle Therapy Cooperative Group
  28. 2012 - present
    MemberLung Disease Committee, Proton Collaborative Group
  29. 2011 - 2022
    MemberLymphoma and Leukemia Exam Board, American Board of Radiology
  30. 2011 - 2018
    MemberAppropriateness Criteria Expert Panel on Lymphoma, American College of Radiology
  31. 2011 - present
    MemberChildren’s Oncology Group
  32. 2011 - present
    MemberHodgkin Lymphoma Committee, Children’s Oncology Group
  33. 2011 - present
    MemberAmerican College of Radiology
  34. 2011 - present
    MemberFlorida Radiological Society
  35. 2009 - 2019
    DirectorThoracic Oncology Team, UF Health Proton Therapy Institute
  36. 2009 - 2019
    DirectorLymphoma Team, UF Health Proton Therapy Institute
  37. 2009 - 2019
    MemberPediatric Team, UF Health Proton Therapy Institute
  38. 2009 - 2018
    MemberInstitutional Review Board, UF Health Shands Hospital
  39. 2008 - 2019
    MemberTumor Board, Thoracic Oncology Program, UF Health Shands Hospital
  40. 2005 - 2009
    MemberRadiologic Society of North America
  41. 2005 - present
    MemberAmerican Society for Radiation Oncology

Publications

Research activities

See a description of research activities.