Otorrinolaringología (ENT)/cirugía de cabeza y cuello

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. A Study to Examine Proteins from Chronic Otitis Media Fluid Samples in Patients undergoing Myringotomy and Possibly a Tube Insertion Procedure

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   During myringotomy and possibly a tube insertion procedure a small amount of fluid that is being removed from the middle ear (whether or not you participate in the study) will be examined for different proteins or it may be saved and used for future research studies.

2. A Study to Evaluate Electrophysiological Measurements in Cochlear Implant Patients

   Rochester, Minn.

   The purpose of this study is to perform electrophysiological (inner ear) measurements to assess hearing function in cochlear implant patients.

    

    

3. A Study Identifying Blood Serum Markers of the Immune System Affecting Different Features of Chronic Rhinosinusitis

   Rochester, Minn.

   The purpose of this study is to find out what immune system processes cause the chronic inflammation that happens with chronic rhinosinusitis (CRS) and if there are different immune system pathways involved among CRS patients.

4. Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults with Partial Deafness

   Rochester, Minn.

   The purpose of this feasibility study is to evaluate whether low-frequency acoustic hearing sensitivity can be preserved in newly implanted adults with partial deafness (considerable low frequency acoustic hearing profiles with severe-to-profound high frequency sensorineural hearing loss) using the HiResolution™ 90K™ Advantage cochlear implant with the HiFocus™ Mid-Scala electrode to support the development of electro-acoustic stimulation technology (EAS).

5. Otorhinolaryngology Normal, Tumor Tissue, Saliva, Stool, and Blood Bank

   Rochester, Minn.

   The purpose of this study is to obtain tissue, blood, saliva, and stool specimens and informed consent from ENT patients in order to build a freezer archive of samples to support ongoing and future developmental studies.

6. Surgical Waste of Skull Base Tumors

   Rochester, Minn.

   The purpose of this study is to collect and store limited identified surgical waste specimens from skull base tumor cases.  We will also collect peripheral blood samples and store PBMC (white blood cells) and serum for each patient.

7. Study of the Preceptis Medical Inc. Hummingbird™ Tympanostomy Tube System in the Otolaryngology Clinic

   Rochester, Minn.

   The objective of this study is to evaluate the safety and performance of the H-TTS for the placement of ear tubes in patients undergoing tympanostomy tube placement in an otolaryngology clinic using local anesthetic.

8. Randomized Trial of Intensity-Modulated Proton Beam Therapy (IMPT) Versus Intensity-Modulated Photon Therapy (IMRT) for the Treatment of Oropharyngeal Cancer of the Head and Neck

   Rochester, Minn., Scottsdale/Phoenix, Ariz.

   The goal of this clinical research study is to compare the side effects of 2 radiation treatments for head and neck cancer. The 2 treatments are intensity modulated photon therapy (IMRT) and intensity modulated proton therapy (IMPT). Participants will also receive chemotherapy along with radiation therapy. IMPT is designed to use beams of proton particles to send radiation to the tumor. IMRT is designed to use beams of photon therapy to send radiation to the tumor. Both of these types of radiation treatment may give a full dose of radiation treatment to the tumor while not damaging as much of the healthy tissue around it. This is an investigational study. IMRT and IMPT are delivered using FDA-approved and commercially available methods. Comparing them is investigational. Up to 360 participants will be enrolled in this study. Up to 250 patients will take part at MD Anderson.

9. A Study of Genital Cytology and Pathology in Patients with Confirmed HPV Associated Oropharyngeal Carcinoma

   Rochester, Minn.

   The purpose of this study is to determine the incidence of concomitant HPV associated genital lesions in female patients with confirmed HPV associated oropharyngeal cancers, to determine the risk of requiring additional procedures or treatments secondary to these diagnoses, and to determine the HPV subtypes and other risk factors associated with genital dysplasia among those with documented HPV status.

10. A Study of Pain Control Following Sinus Surgery

    Rochester, Minn.

    The purpose of this study is to determine the degree to which pain following ESS can be adequately controlled by non-opioid medications. It will also determine whether post-ESS narcotic use can be avoided entirely, or at least significantly limited.  The results of this study will help to develop a standardized approach to pain management in the post-ESS setting and help to clarify the role of non-opioid pain medications. The ultimate goal would be to positively affect opioid prescribing patterns among surgeons who perform ESS in order to significantly reduce the quantity of opioids prescribed to patients while continuing to adequately manage patients' pain.