Verapamil (intravenous route)

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Appropriate studies have not been performed on the relationship of age to the effects of verapamil in the pediatric population. Safety and efficacy have not been established .

No information is available on the relationship of age to the effects of verapamil in geriatric patients. However, elderly patients are more likely to have age-related kidney or liver problems, which may require an adjustment in the dose for patients receiving verapamil .

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Colchicine
• Dofetilide
• Flibanserin
• Lomitapide

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abametapir
• Acalabrutinib
• Acebutolol
• Adenosine
• Afatinib
• Alfentanil
• Alprazolam
• Amiodarone
• Apixaban
• Aprepitant
• Atazanavir
• Atenolol
• Atorvastatin
• Avacopan
• Avapritinib
• Bedaquiline
• Benzhydrocodone
• Betaxolol
• Betrixaban
• Bisoprolol
• Bosutinib
• Brexpiprazole
• Brigatinib
• Budesonide
• Bupivacaine
• Bupivacaine Liposome
• Buprenorphine
• Capivasertib
• Carbamazepine
• Cariprazine
• Carteolol
• Carvedilol
• Celiprolol
• Ceritinib
• Cilostazol
• Clarithromycin
• Clonidine
• Clopidogrel
• Clozapine
• Cobicistat

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amlodipine
• Buspirone
• Dalfopristin
• Digitoxin
• Dutasteride
• Flecainide
• Indinavir
• Lithium
• Metformin
• Midazolam
• Oxcarbazepine
• Pancuronium
• Quinidine
• Quinupristin
• Rifapentine
• St John's Wort
• Tedisamil
• Telithromycin
• Tubocurarine
• Vecuronium

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Tobacco

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol
• Grapefruit Juice

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Atrial fibrillation (type of abnormal heart rhythm) or
• Cardiogenic shock (shock caused by heart attack) or
• Congestive heart failure, severe or
• Heart block (type of abnormal heart rhythm, can use if have a pacemaker that works properly) or
• Lown-Ganong-Levine syndrome (type of abnormal heart rhythm) or
• Severe hypotension (blood pressure too low) or
• Sick sinus syndrome (type of abnormal heart rhythm, can use if have a pacemaker that works properly) or
• Ventricular tachycardia (type of abnormal heart rhythm) or
• Wolff-Parkinson-White syndrome (type of abnormal heart rhythm)—Should not use in patients with these conditions .

• Kidney disease or
• Liver disease—Use with caution. The effects of this medicine may be increased because of slower removal from the body .

Less common

• Blurred vision
• chest pain or discomfort
• confusion
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• fast, slow, pounding, or irregular heartbeat or pulse
• lightheadedness, dizziness, or fainting
• shortness of breath
• sweating
• unusual tiredness or weakness

Rare

• Cough
• difficulty breathing
• noisy breathing
• tightness in chest
• wheezing

Incidence not known

• Convulsions
• loss of bladder control
• muscle spasm or jerking of all extremities
• sudden loss of consciousness

Less common

• Headache

Rare

• Hives or welts
• itching
• nausea
• redness of skin
• skin rash
• stomach soreness or discomfort

Incidence not known

• Discouragement
• feeling of constant movement of self or surroundings
• feeling sad or empty
• increased sweating
• irritability
• lack of appetite
• loss of interest or pleasure
• sensation of spinning
• sleepiness
• tiredness
• trouble concentrating
• trouble sleeping
• uncontrolled eye movements