Description
Sodium glycerophosphate injection is a phosphate replacement given in patients who are unable to get enough phosphorus or who cannot receive a phosphate supplement by mouth or feeding tube.
This medicine is to be given only by or under the direct supervision of your doctor.
This product is available in the following dosage forms:
- Solution
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of sodium glycerophosphate in children 12 years of age and older. However, children are more likely to have systemic toxicity, which may require caution in patients receiving this medicine.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sodium glycerophosphate in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Congestive heart failure or
- Kidney disease or
- Liver disease—Use with caution. May make these conditions worse.
- Hypercalcemia (high calcium levels in the blood) or
- Hypernatremia (high sodium levels in the blood) or
- Hyperphosphatemia (high phosphorus levels in the blood) or
- Hypocalcemia (low calcium levels in the blood)—Should not be used in patients with these conditions.
Proper Use
A nurse or other trained health professional will give you or your child this medicine in a medical facility. Glycophos® is added to your or your child's parenteral nutrition (PN) admixture. After mixing, it is given through an IV catheter that is placed into a vein.
Precautions
It is very important that your doctor check your or your child's progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly. Blood and urine tests will be needed to check for unwanted effects.
This medicine may cause blood clotting problems. Check with your doctor right away if you have anxiety, chest pain, cough, dizziness or lightheadedness, fainting, fast heartbeat, or trouble breathing.
This medicine may cause hyperphosphatemia, which can lead to hypocalcemia. Check with your doctor right away if you have confusion, irregular heartbeats, mood or mental changes, muscle cramps in the hands, feet, legs, or face, numbness and tingling around the mouth, fingertips, or feet, seizures, stomach cramps, tremor, or trouble breathing.
Check with your doctor right away if you have bloating or swelling of the face, arms, hands, lower legs, or feet, decrease in amount of urine, noisy, rattling, or trouble breathing, rapid weight gain, or tingling of the hands or feet. These may be symptoms of fluid retention (too much water in the body) and edema (swelling).
This medicine may cause a serious allergic reaction, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.
This medicine contains aluminum which can cause harm especially to premature babies, which may damage the brain and can be life-threatening. Talk to your doctor if you have concerns.
Check with your doctor right away if you have drowsiness, loss of appetite, mood or mental changes, muscle spasms or twitching, nausea or vomiting, seizures, trembling, or unusual tiredness or weakness. These may be symptoms of hypomagnesemia (low magnesium levels in the blood).
This medicine may cause infusion reactions, which can lead to vein irritation, damage, or thrombosis. Check with your doctor right away if you have tenderness, pain, swelling, warmth, skin discoloration, or prominent superficial veins over affected area.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Incidence not known
- Agitation
- anxiety
- bluish color
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- changes in skin color
- chest pain, discomfort, or tightness
- coma
- confusion
- cough
- decreased urine output
- depression
- difficulty swallowing
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- drowsiness
- fainting
- fast or irregular heartbeats
- high blood pressure
- hives, itching, skin rash
- hostility
- irritability
- lethargy
- loss of appetite
- mood or mental changes
- muscle cramps in the hands, arms, feet, legs, or face
- muscle twitching
- nausea
- no blood pressure or pulse
- numbness and tingling around the mouth, fingertips, or feet
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- rapid weight gain
- restlessness
- seizures
- stomach cramps
- stopping of the heart
- stupor
- sweating
- swelling of face, ankles, or hands
- swelling of the feet or lower legs
- tenderness
- tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area
- tremor
- trouble breathing
- unconsciousness
- unusual tiredness or weakness
- vomiting
- weight gain
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Diarrhea
- stomach pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
DRG-80011969
