Description and Brand Names

Drug information provided by: IBM Micromedex

US Brand Name

  1. Lynparza

Descriptions


Olaparib is used as maintenance treatment in patients with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer with a certain type of inherited (germline) or acquired (somatic) abnormal BRCA gene. Your doctor will test for the presence of this gene. It is used in patients who have received complete or partial treatment with platinum-based cancer medicines.

Olaparib is used together with bevacizumab as maintenance treatment in patients with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer with a certain type of abnormal BRCA gene or a positive tumor test for genomic instability called HRD. Your doctor will test for the presence of this gene. It is used in patients who have received complete or partial treatment with platinum-based cancer medicines.

Olaparib is also used to treat ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that has come back. It is used in patients who have received complete or partial treatment with platinum-based cancer medicines.

Olaparib is also used to treat advanced ovarian cancer in patients who have received three or more previous lines of cancer treatment. It is used if the cancer cells have the germline BRCA mutations. Your doctor will use a special test to look for these mutations.

Olaparib is also used to treat HER2-negative metastatic (cancer that has spread) breast cancer in patients who have been treated with other cancer medicines. It is used if the cancer cells have the germline BRCA mutations. Your doctor will use a special test to look for these mutations.

Olaparib is also used as maintenance treatment in patients with metastatic (cancer that has spread) pancreas cancer with a certain type of inherited (germline) abnormal BRCA gene, whose disease has not progressed and who have been treated with platinum-based cancer medicines for at least 16 weeks.

Olaparib is also used to treat metastatic castration-resistant prostate cancer (prostate cancer that has spread and is resistant to medical or surgical treatments that lower testosterone) in patients who have been treated with other cancer medicines (eg, abiraterone, enzalutamide). It is used if the cancer cells have a certain type of inherited (germline) or acquired (somatic) abnormal HRR gene. Your doctor will test for the presence of this gene.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet