Description and Brand Names

Drug information provided by: IBM Micromedex

US Brand Name

  1. Orkambi


Lumacaftor and ivacaftor combination is used to treat cystic fibrosis (CF) in patients 2 years of age and older. It is only used for patients who have two copies of F508del mutation in their CF transmembrane conductance regulator (CFTR) gene. Your doctor will use a test to check for the mutation before you receive the medicine.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Granule