Before Using

Drug information provided by: IBM Micromedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of immune globulin injection in children. Some of the products are only used in children who are 2, 3, or 15 years of age and older, and other products are not approved for use in children. Immune globulin injection is used to treat primary humoral immunodeficiency (PI), idiopathic thrombocytopenic purpura (ITP), and chronic immune thrombocytopenic purpura in children. Safety and efficacy have not been established for use in chronic inflammatory demyelinating polyneuropathy (CIDP) or multifocal motor neuropathy (MMN).

Appropriate studies have not been performed on the relationship of age to the effects of Gamastan® in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of immune globulin injection in the elderly. However, elderly patients are more likely to have age-related blood clotting problems, kidney disease, or heart disease, which may require caution for patients receiving immune globulin injection.

Appropriate studies have not been performed on the relationship of age to the effects of Gamastan® in the elderly. Safety and efficacy have not been established.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Allergy to corn—Use with caution. May cause an allergic reaction to occur again.
  • Anemia, history of or
  • Bleeding problems, history of or
  • Hyponatremia (low sodium in the blood) or
  • Kidney problems—Use with caution. May make these conditions worse.
  • Atherosclerosis (hardening of the arteries), history of or
  • Blood clotting problems, history of or
  • Diabetes or
  • Heart attack or stroke, recent or
  • Heart or blood vessel disease or
  • Hyperproteinemia (high protein in the blood) or
  • Hyperviscosity (thick blood), known or suspected or
  • Hypovolemia (low blood volume or major loss of body fluids) or
  • IgA (immunoglobulin A) deficiency with antibodies against IgA or
  • Paraproteinemia (paraproteins in the blood) or
  • Sepsis (serious infection in the body)—Use with caution. May cause side effects to become worse.
  • Hereditary intolerance to fructose or sucrose or
  • IgA (immunoglobulin A) deficiency with antibodies against IgA—Gammaplex® should not be used in patients with these conditions.
  • Hyperprolinemia (too much proline in the blood) or
  • IgA (immunoglobulin A) deficiency with antibodies against IgA—Hizentra® and Privigen® should not be used in patients with these conditions.
  • IgA (immunoglobulin A) deficiency with antibodies against IgA—Cuvitru®, Gamastan®, and Octagam® should not be used in patients with this condition.