Hydralazine (injection route)

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Appropriate studies on the relationship of age to the effects of hydralazine injection have not been performed in the pediatric population. However, no pediatric-specific problems have been documented to date.

No information is available on the relationship of age to the effects of hydralazine injection in geriatric patients.

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Haloperidol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Enteral Nutrition

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Angina (severe chest pain) or
• Blood disease or
• Heart attack, history of or
• Heart rhythm problems or
• Hypotension (low blood pressure) or
• Peripheral neuritis (nerve problem) or
• Stroke, history of or
• Systemic lupus erythematosus—Use with caution. May make these conditions worse.

• Coronary artery disease or
• Mitral valvular rheumatic heart disease—Should not be used in patients with these conditions.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

More common

• Am, back, or jaw pain
• chest pain or discomfort
• chest tightness or heaviness
• fast, pounding, or irregular heartbeat or pulse
• nausea
• shortness of breath
• sweating

Less common

• Black, tarry stools
• blindness or vision changes
• blurred vision
• burning of the face or mouth
• burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings
• chills
• clumsiness or unsteadiness
• confusion
• cough
• difficult or labored breathing
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fever and sore throat
• lower back or side pain
• painful or difficult urination
• pale skin
• shakiness in the legs, arms, hands, feet
• swelling
• swollen, painful, or tender lymph glands in the neck, armpit, or groin
• trembling or shaking of the hands or feet
• ulcers, sores, or white spots in the mouth
• unusual bleeding or bruising
• unusual tiredness or weakness
• weakness in the hands or feet

Rare

• Dark urine
• general tiredness and weakness
• light-colored stools
• nausea and vomiting
• upper right abdominal or stomach pain
• yellow eyes and skin

Symptoms of overdose

• Feeling of warmth
• headache
• redness of the face, neck, arms, and occasionally, upper chest

More common

• Diarrhea
• headache
• loss of appetite
• weight loss

Less common

• Difficulty having a bowel movement (stool)
• difficulty with moving
• dizziness
• feeling anxious or depressed
• muscle cramps, pain, or stiffness
• pain in the joints
• rash, hives or welts, itching