Description and Brand Names
Drug information provided by: IBM Micromedex
US Brand Name
Eculizumab injection is used to treat a type of blood disease called paroxysmal nocturnal hemoglobinuria (PNH). This medicine helps reduce red blood cell destruction or breakdown (hemolysis) in patients with PNH.
This medicine is also used to treat a serious kidney disorder called atypical hemolytic uremic syndrome (aHUS).
Eculizumab injection is also used to treat a nerve and muscle disease called generalized myasthenia gravis (gMG) in patients who are anti-acetylcholine receptor (AchR) antibody positive.
Eculizumab injection is also used to treat neuromyelitis optica spectrum disorder (NMOSD), a rare disorder that causes inflammation of the nerves of the eyes and spinal cord. It is used in patients who are anti-aquaporin-4 (AQP4) antibody positive.
Eculizumab injection is a monoclonal antibody that works on the immune system.
This medicine is available only under a restricted distribution program called Soliris® REMS (Risk Evaluation and Mitigation Strategy) Program.
This product is available in the following dosage forms: