Cefditoren pivoxil (oral route)

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of cefditoren in children less than 12 years of age with use in other age groups.

This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aluminum Carbonate, Basic
• Aluminum Hydroxide
• Aluminum Phosphate
• Calcium Carbonate
• Dihydroxyaluminum Aminoacetate
• Dihydroxyaluminum Sodium Carbonate
• Famotidine
• Magaldrate
• Magnesium Carbonate
• Magnesium Hydroxide
• Magnesium Oxide
• Magnesium Trisilicate
• Probenecid

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Carnitine deficiency—May be worsened by cefditoren

• Kidney disease—Cefditoren may need to be given at a lower dose

Rare

• Allergic reaction, such as, itching, pain, redness, or swelling of eye or eyelid, watering of eyes, troubled breathing or wheezing, severe skin rash or hives, flushing, headache, fever, chills, runny nose, increased sensitivity to sunlight, joint pain, swollen glands
• leukopenia, such as, black, tarry stools, chest pain, chills, cough, fever, painful or difficult urination, shortness of breath, sore throat, sores, ulcers, or white spots on lips or in mouth, swollen glands, unusual bleeding or bruising, unusual tiredness, or weakness
• pseudomembranous colitis, such as, abdominal or stomach cramps, pain, bloating, abdominal tenderness, diarrhea, watery and severe, which may also be bloody, fever, increased thirst, nausea or vomiting, unusual tiredness or weakness, or unusual weight loss
• or thrombocythemia, such as, pain, warmth or burning in fingers, toes, and legs, dizziness, problems with vision or hearing

More Common

• Diarrhea
• nausea
• or vaginal moniliasis, such as, thick whitish discharge from the vagina or cervical canal

Less common

• Abdominal pain
• Dyspepsia, such as, acid or sour stomach, belching, heartburn, indigestion, or stomach discomfort, upset or pain
• or headache

Rare

• Abnormal dreams
• anorexia, such as, loss of appetite
• asthenia, such as, lack or loss of strength
• constipation
• dizziness
• dry mouth
• dysgeusia, such as, taste perversion
• eructation, such as, belching, bloated full feeling, excess air or gas in stomach
• fever
• flatulence, such as, passing of gas
• fungal infection
• gastritis, such as, burning feeling in chest or stomach, tenderness in stomach area, stomach upset, or indigestion
• headache
• hyperglycemia, such as, blurred vision, dry mouth, fatigue, flushed, dry skin, fruit-like breath odor, increased hunger, increased thirst, increased urination, loss of consciousness, nausea, stomachache, sweating, troubled breathing, unexplained weight loss, vomiting
• increased appetite
• insomnia, such as, sleeplessness
• leukorrhea, such as, increase in amount of clear vaginal discharge, white vaginal discharge
• mouth ulceration
• myalgia, such as, muscle pain
• nervousness
• oral moniliasis, such as, sore mouth or tongue, white patches in mouth, tongue, or throat
• pain
• peripheral edema, such as, bloating or swelling of face, arms, hands, lower legs, or feet, rapid weight gain, tingling of hands or feet, unusual weight gain or loss
• pharyngitis, such as, body aches or pain, congestion, cough, dryness or soreness of throat, fever, hoarseness, runny nose, tender, swollen glands in neck, trouble in swallowing, or voice changes
• pruritus, such as, itching skin
• rash
• rhinitis, such as, stuffy nose, runny nose, or sneezing
• sinusitis, such as, pain or tenderness around eyes and cheekbones, fever, stuffy or runny nose, headache, cough, shortness of breath or troubled breathing, tightness of chest or wheezing
• somnolence, such as, sleepiness or unusual drowsiness
• stomatitis, such as, swelling or inflammation of the mouth
• sweating
• urinary frequency
• urticaria, such as, hives or welts, itching, redness of skin, or rash
• vaginitis
• vomiting
• or weight loss