Aminocaproic acid (intravenous route)

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Appropriate studies have not been performed on the relationship of age to the effects of aminocaproic acid injection in the pediatric population. Safety and efficacy have not been established.

No information is available on the relationship of age to the effects of aminocaproic acid injection in geriatric patients.

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Anti-Inhibitor Coagulant Complex
• Tretinoin

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood clots, active or
• Disseminated intravascular coagulation or DIC (blood clotting problem)—Should not be used in patients with these conditions.

• Blood clots, history of or
• Hematuria (blood in the urine)—Use with caution. May make these conditions worse.

• Kidney disease—The effects of this medicine may be increased because of slower removal of the medicine from the body.

Incidence not known

• Anxiety
• black, tarry stools
• bleeding gums
• bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• blood in the urine or stools
• blurred vision
• break in the skin, especially associated with blue-black discoloration, swelling, or drainage of fluid
• change in the ability to see colors, especially blue or yellow
• chest pain or discomfort
• chills
• confusion
• cough or hoarseness
• dark-colored urine
• decreased frequency or amount of urine
• difficult or labored breathing
• difficulty with moving
• difficulty with speaking
• difficulty with swallowing
• dizziness or lightheadedness
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• double vision
• fainting
• fast heartbeat
• fever with or without chills
• general feeling of discomfort or illness
• general feeling of tiredness or weakness
• headache
• hives
• inability to move arms, legs, or facial muscles inability to speak
• increased thirst
• itching of the skin
• joint pain
• loss of appetite
• lower back or side pain
• muscle aching or cramping
• muscle cramps or spasms
• muscle pain or stiffness
• muscular pain, tenderness, wasting, or weakness
• nausea and vomiting
• numbness and tingling of the face, fingers, or toes
• pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
• painful or difficult urination
• pale, bluish-colored, or cold hands or feet
• pinpoint red spots on the skin
• problems with bleeding or clotting
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• shortness of breath
• skin rash
• slow or irregular heartbeat
• slow speech
• sore throat
• sores, ulcers, or white spots on the lips or in the mouth
• sudden shortness of breath or troubled breathing
• sweating
• swelling
• swelling of the face, fingers, or lower legs
• swollen glands
• swollen joints
• tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
• tightness in the chest
• troubled breathing
• unusual bleeding or bruising
• unusual tiredness or weakness
• vomiting
• weak or absent pulses in the legs
• weight gain
• wheezing

Incidence not known

• Abdominal or stomach pain
• confusion as to time, place, or person
• continuing ringing or buzzing or other unexplained noise in the ears
• decreased vision
• diarrhea
• ejaculation without semen
• hearing loss
• holding false beliefs that cannot be changed by fact
• mood or mental changes
• seeing, hearing, or feeling things that are not there
• stuffy nose
• unusual excitement, nervousness, or restlessness
• watery eyes