Overview

Nonulcer stomach pain is a term for recurring signs and symptoms of indigestion that have no obvious cause. Nonulcer stomach pain is also called functional dyspepsia (dis-PEP-see-uh) or nonulcer dyspepsia.

Nonulcer stomach pain is common and can be long lasting. The condition can cause signs and symptoms that resemble those of an ulcer, such as pain or discomfort in your upper abdomen, often accompanied by bloating, belching and nausea.

Symptoms

Signs and symptoms of nonulcer stomach pain may include:

  • A burning sensation or discomfort in your upper abdomen or lower chest, sometimes relieved by food or antacids
  • Bloating
  • Belching
  • An early feeling of fullness when eating
  • Nausea

When to see a doctor

Make an appointment with your doctor if you experience persistent signs and symptoms that worry you.

Seek immediate medical attention if you experience:

  • Bloody vomit
  • Dark, tarry stools
  • Shortness of breath
  • Pain that radiates to your jaw, neck or arm
  • Unexplained weight loss

Causes

It's not clear what causes nonulcer stomach pain. Doctors consider it a functional disorder, which means it's not found to be caused by a specific disease or diagnosable disorder.

Risk factors

Factors that can increase the risk of nonulcer stomach pain include:

  • Female sex
  • Older age
  • Use of certain over-the-counter pain relievers, such as aspirin and ibuprofen (Advil, Motrin IB, others), which can cause stomach problems
  • Smoking
  • Anxiety or depression
  • History of childhood physical or sexual abuse

Nonulcer stomach pain care at Mayo Clinic

Dec. 20, 2017
References
  1. Ferri FF. Nonulcerative dyspepsia. In: Ferri's Clinical Advisor 2018. Philadelphia, Pa.:Elsevier; 2018. https://www.clinicalkey.com. Accessed Nov. 6, 2017.
  2. Longstreth GF, et al. Functional dyspepsia in adults. http://www.uptodate.com/home. Accessed July 27, 2017.
  3. Goldman L, et al. Functional gastrointestinal disorders. In: Goldman's Cecil Medicine. 25th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com. Accessed Nov. 6, 2017.
  4. Indigestion. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/indigestion/index.aspx. Accessed Nov. 6, 2017.
  5. Dyspepsia. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Nov. 6, 2017.
  6. Moayyed PM, et al. ACG and CAG Clinical Guideline: Management of dyspepsia. American Journal of Gastroenterology. 2017;112:988.
  7. Brown A. Decision Support System. Mayo Clinic, Rochester, Minn. Sept. 11, 2017.
  8. Kashyap PC (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 20, 2017.
  9. Stanghellini V, et al. Gastroduodenal disorders. Gastroenterology. 2016;50:1380.