Print Monoclonal gammopathy of undetermined significance (MGUS) care at Mayo ClinicYour Mayo Clinic care teamMayo Clinic's MGUS teams are led by specialists in blood conditions (hematologists). The team includes other specialists as needed, such as those who specialize in cancer (oncologists) or kidney diseases (nephrologists). This team of specialists focuses on helping you and coordinating care. Advanced diagnosis and treatmentMayo Clinic specialists have experience in diagnosing MGUS, related cancers and other complications. Their expertise enables you to get appropriate and timely care. Expertise and rankings Experience. Mayo Clinic's experts care for more than 5,000 people with MGUS each year. Judging risk. Mayo Clinic created a model that can predict the risk of MGUS progressing to multiple myeloma. Nationally recognized expertise Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic Comprehensive Cancer Center meets the strict standards for a U.S. National Cancer Institute comprehensive cancer center. These standards recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment. Locations, travel and lodgingMayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states. For more information on visiting Mayo Clinic, choose your location below: Mayo Clinic's campus in Arizona Mayo Clinic's campus in Florida Mayo Clinic's campus in Minnesota Mayo Clinic Health System Mayo Clinic Healthcare, located in London Costs and insuranceMayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need. Learn more about appointments at Mayo Clinic. Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card. More information about billing and insurance: Mayo Clinic in Arizona, Florida and Minnesota Mayo Clinic Health System By Mayo Clinic Staff Request an appointment Doctors & departments Dec. 30, 2025 Print Living with monoclonal gammopathy of undetermined significance (MGUS)? Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Blood Cancers & Disorders Discussions Does anyone else have MGUS? 1135 Replies Sat, Jan 31, 2026 chevron-right AML successful treatment 75 Replies Sat, Jan 31, 2026 chevron-right I have JAK2 ET and MPN: Anyone else have these symptoms? 111 Replies Sat, Jan 31, 2026 chevron-right See more discussions Related Associated Procedures Bone marrow biopsy Complete blood count (CBC) Creatinine test X-ray Show more associated procedures Products & Services A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Monoclonal gammopathy of undetermined significance (MGUS)Symptoms&causesDiagnosis&treatmentDoctors&departmentsCare atMayoClinic CON-20166978 Diseases & Conditions Monoclonal gammopathy of undetermined significance (MGUS)