Liver disease

Aug. 07, 2025

Liver disease care at Mayo Clinic

  • Your Mayo Clinic care team. At Mayo Clinic, a multidisciplinary team of specialists work together to evaluate and treat each person. Specialists in gastroenterology and hepatology and liver transplant at Mayo Clinic diagnose and treat adults with liver disease. The Hepatobiliary Clinic and specialists in the Liver Transplant Interest Group help coordinate care. The Hyperoxaluria Center specializes in researching and treating a condition called oxalosis that sometimes requires a kidney and liver transplant.

    Specialists in pediatric hepatology and liver transplant diagnose and treat children with liver disease.

  • Advanced diagnosis and treatment. You'll have access to the latest technology and specialized techniques to improve diagnosis and care at Mayo Clinic.

    Mayo Clinic researchers invented a new, noninvasive way to detect hardening of the liver. Magnetic resonance elastography (MRE) combines MRI imaging with sound waves to create a visual map (elastogram) showing the stiffness of liver tissue. At Mayo Clinic, MRE may be done as part of a conventional MRI exam for liver disease.

  • Care focused on you. Mayo Clinic team members work together closely in planning each person's care. This collaboration means your appointments will be coordinated and your test results will be ready quickly. Evaluation and treatment that might take months elsewhere can typically be done in only a matter of days at Mayo Clinic.

Expertise and rankings

Experience

Each year, Mayo Clinic specialists treat more than 30,000 people with liver diseases.

Surgical expertise

Mayo Clinic liver transplant surgeons use state-of-the-art technology to successfully treat people with liver failure and other complications of liver conditions. Their expertise with living-donor transplant, a fast-track recovery process and multiorgan transplants are part of why people turn to the Mayo Clinic Liver Transplant Program. With campuses in Arizona, Florida and Minnesota, the Mayo Clinic Liver Transplant Program has one of the best long-term survival rates in the country.

Research leaders

Mayo Clinic's researchers often collaborate with colleagues throughout the United States and internationally who are committed to improving outcomes and care for people with liver disease. They conduct laboratory studies, clinical trials and other research on many aspects of conditions related to liver disease, such as cell therapies and bioartificial livers.

  1. Loscalzo J, et al., eds. Approach to the patient with liver disease. In: Harrison's Principles of Internal Medicine. 21st ed. McGraw-Hill; 2022. https://accessmedicine.mhmedical.com. Accessed Nov. 8, 2023.
  2. How liver disease progresses. American Liver Foundation. https://liverfoundation.org/about-your-liver/how-liver-diseases-progress/. Accessed Nov. 14, 2023.
  3. AskMayoExpert. Metabolic and alcohol-associated liver disease (adult). Mayo Clinic; 2023.
  4. AskMayoExpert. Cirrhosis (adult). Mayo Clinic; 2023.
  5. Feldman M, et al. Liver disease caused by anesthetics, chemicals, toxins, and herbal and dietary supplements. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 11th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Nov. 14, 2023.
  6. Elsevier Point of Care. Clinical Overview: Nonalcoholic fatty liver disease. https://www.clinicalkey.com. Accessed Nov. 14, 2023.
  7. Neshat SY, et al. Liver disease: Induction, progression, immunological mechanisms, and therapeutic interventions. International Journal of Molecular Sciences. 2021; doi:10.3390/ijms22136777.
  8. Malnick SDH, et al. Fatty liver disease — alcoholic and nonalcoholic: Similar but different. International Journal of Molecular Sciences. 2022; doi:10.3390/ijms232416226.
  9. Alcohol and public health: Frequently asked questions. Centers for Disease Control and Prevention. https://www.cdc.gov/alcohol/faqs.htm. Accessed Nov. 14, 2023.
  10. Fighting fatty liver: Steps against a silent disease. NIH News in Health. https://newsinhealth.nih.gov/2021/10/fighting-fatty-liver. Accessed Nov. 14, 2023.
  11. 13 ways to a healthy liver. American Liver Foundation. https://liverfoundation.org/resource-center/blog/13-ways-to-a-healthy-liver/. Nov. 14, 2023.
  12. Ami TR. Allscripts EPSi. Mayo Clinic. Nov. 14, 2023.