Survival rates

The survival rates for invasive lobular carcinoma (ILC) and other types of breast cancer are quite good. The cancer often can be cured when it's found early. Even when a cure isn't possible, treatments often can slow its growth and extend your life.

People diagnosed with cancer often want to know the survival rates. It's OK to be curious about the survival rates for your cancer. Some people find these numbers helpful because they offer a general sense of what to expect and help put the diagnosis in perspective. It's also OK if these numbers don't feel helpful to you. There are people who find the statistics confusing, discouraging or overwhelming.

Survival statistics can provide general information about the seriousness of the situation, but they can't predict what will happen in any one person. These statistics include thousands of people with breast cancer, including people of different ages, with different health conditions and with different treatment histories.

Keep in mind that your healthcare team uses much more detailed information when talking with you about your individual prognosis and treatment options.

Survival statistics

Survival rates for invasive lobular carcinoma are the same as survival rates for breast cancer in general.

The U.S. National Cancer Institute (NCI) tracks cancer survival rates in the United States. NCI breaks down the rates by how far the cancer has spread, rather than by stage.

  • Localized cancer, which means the cancer is only in the breast, has a 5-year relative survival rate of 100%.
  • Regional cancer, which means the cancer has spread to nearby lymph nodes, has a 5-year relative survival rate of 88%.
  • Distant cancer, which means the cancer has spread to other parts of the body, has a 5-year relative survival rate of 34%.

These are the survival rates for breast cancer in general. Survival rates vary depending on whether the cancer cells have hormone receptors or make extra HER2. Your own chances for survival depend greatly on the details of your cancer.

Prognosis

Cancer prognosis describes how likely it is that a cancer can be treated successfully or cured. Healthcare professionals estimate prognosis using information about the cancer and your overall health. To better understand your personal prognosis, talk with your healthcare team. They can explain the factors that affect your situation.

Having an invasive lobular carcinoma generally doesn't affect prognosis. This type of cancer has a similar prognosis to the other main type, called invasive ductal carcinoma.

Things that can affect the prognosis for invasive lobular carcinoma and other breast cancers include:

  • Age at diagnosis. Breast cancer that happens in older people tends to have a better prognosis than cancer that happens in younger people. Invasive lobular carcinoma tends to happen at an older age than other types of breast cancer.
  • Cancer grade. Grade 1 and 2 cancers tend to grow more slowly and have a better prognosis than grade 3 cancers. Most invasive lobular carcinomas are grade 1 or 2.
  • HER2 status. Cancer cells that make extra HER2 tend to grow faster. But there are many treatments that target HER2. Because treatment is so effective, having a HER2-positive breast cancer gives a better prognosis. Most invasive lobular carcinomas are HER2 negative.
  • Hormone receptor status. Cancers that are hormone receptor positive have a better prognosis than those that don't. Most invasive lobular carcinomas are hormone receptor positive.
  • The size of the cancer in the breast. A small cancer may be easier to remove completely and have a lower risk of spreading, so it has a better prognosis.
  • Whether the lymph nodes contain cancer. Cancer that spreads to the lymph nodes has a higher risk of spreading to other parts of the body. If the cancer hasn't spread to the lymph nodes, the prognosis is better.

What you can do

After breast cancer treatment, healthcare professionals generally recommend making healthy choices that are good for anyone who wants improved health: Eat a balanced diet, exercise, maintain a weight that's healthy for you and limit the amount of alcohol you drink. For people with breast cancer, these healthy choices also might lower the risk of recurrent breast cancer.

Try to:

  • Avoid alcohol. Research links drinking alcohol to a higher risk of breast cancer, but it's not clear whether alcohol raises the risk of the cancer coming back. If you choose to drink alcohol, limit how often you drink and keep the amount small. For overall health, drink one or fewer drinks a day. Do not drink every day. The less you drink, the better.
  • Follow a healthy diet. Choose a diet that's rich in fruits, vegetables and whole grains. Limit how much red meat, processed meat and sugar you eat.
  • Stay active. Aim to exercise most days of the week. If you don't exercise regularly, get your healthcare professional's OK first. Start out with short sessions of an activity you enjoy and build up the amount of exercise over time.
  • Strive for a healthy weight. Ask your healthcare professional what weight is healthy for you. If your weight is healthy, work to maintain it. If you need to lose weight, aim to do so slowly. Start by making healthy choices, such as eating fewer calories, moving more and sitting less.

Talk with your healthcare team about other things you can do to lower your risk of recurrence. Also follow your care team's advice on follow-up exams and tests after you finish cancer treatment.

Aug. 07, 2026

Living with invasive lobular carcinoma (ILC)?

Connect with others like you for support and answers to your questions in the Breast Cancer support group on Mayo Clinic Connect, a patient community.

Breast Cancer Discussions

rozv
Has anyone changed from Anastrozole to Exemestane?

27 Replies Fri, Aug 07, 2026

taken58
Has anyone had a swollen lymph node under their armpit?

20 Replies Wed, Aug 05, 2026

thielmann1
Triple Negative Breast Cancer: What treatments are you having?

259 Replies Mon, Aug 03, 2026

See more discussions
  1. Bleiweiss IJ. Pathology of breast cancer. https://www.uptodate.com/contents/search. Accessed May 8, 2026.
  2. Dabbs DJ. Lobular neoplasia and invasive lobular carcinoma. In: Breast Pathology. 3rd ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed May 8, 2026.
  3. Niederhuber JE, et al., eds. Cancer of the breast. In: Abeloff's Clinical Oncology. 6th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed May 8, 2026.
  4. Breast cancer. National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed May 8, 2026.
  5. Breast cancer risk reduction. National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed May 8, 2026.
  6. AskMayoExpert. Hot flashes. Mayo Clinic; 2026.
  7. Hebbard P, et al. Diffuse gastric and lobular breast cancer syndrome. https://www.uptodate.com/contents/search. Accessed May 8, 2026.
  8. Tyler DS, et al., eds. Diseases of the breast. In: Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 22nd ed. Elsevier; 2026. https://www.clinicalkey.com. Accessed April 13, 2026.
  9. Abraham J, et al., eds. Breast cancer. In: The Bethesda Handbook of Clinical Oncology. 6th ed. ProQuest Ebook Central. Wolters Kluwer; 2023. Accessed April 13, 2026.
  10. DeVita VT Jr, et al., eds. Breast cancer. In: DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. ProQuest Ebook Central. Wolters Kluwer; 2023. Accessed April 13, 2026.
  11. AskMayoExpert. Breast cancer screening and options for supplemental screening in the dense breast. Mayo Clinic; 2024.
  12. Breast cancer screening and diagnosis. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=2&id=1421. Accessed April 13, 2026.
  13. Breast cancer. RadiologyInfo.org. https://www.radiologyinfo.org/en/info/breast-cancer. Accessed April 16, 2026.
  14. Tumor grade. National Cancer Institute. https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-grade. Accessed April 16, 2026.
  15. Protocol for the examination of biopsy specimens from patients with invasive carcinoma of the breast. College of American Pathologists. https://www.cap.org/protocols-and-guidelines/cancer-reporting-tools/cancer-protocol-templates. Accessed April 13, 2026.
  16. Template for reporting results of biomarker testing of specimens from patients with carcinoma of the breast. College of American Pathologists. https://www.cap.org/protocols-and-guidelines/cancer-reporting-tools/cancer-protocol-templates. Accessed April 13, 2026.
  17. Ki-67 proliferation index. National Cancer Institute. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/ki-67-proliferation-index. Accessed April 16, 2026.
  18. American College of Surgeons. Breast. In: AJCC Cancer Staging System. American College of Surgeons; 2026. https://online.statref.com. Accessed April 7, 2026.
  19. Cancer stat facts: Invasive lobular carcinoma. National Cancer Institute. https://seer.cancer.gov/statfacts/html/ilc.html. Accessed May 8, 2026.
  20. Cancer stat facts: Female breast cancer. National Cancer Institute. https://seer.cancer.gov/statfacts/html/breast.html. Accessed April 27, 2026.
  21. Klimberg VS, et al., eds. Bland and Copeland's The Breast: Comprehensive Management of Benign and Malignant Diseases. 6th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed April 13, 2026.
  22. Cutaneous presentations of breast cancer. VisualDx. https://www.visualdx.com. Accessed April 13, 2026.
  23. Corso G, et al. Invasive lobular carcinoma: Strategies and perspectives from the lobular breast cancer research group. Cancer Treatment Reviews. 2025; doi:10.1016/j.ctrv.2025.103001.
  24. Cancer stat facts: Female breast cancer subtypes. National Cancer Institute. https://seer.cancer.gov/statfacts/html/breast-subtypes.html. Accessed May 14, 2026.
  25. Rock CL, et al. American Cancer Society nutrition and physical activity guide for cancer survivors. CA A Cancer Journal for Clinicians. 2022; doi:10.3322/caac.21719.
  26. Breast SPOREs. National Cancer Institute. https://dctd.cancer.gov/research/spores/focus-area/breast. Accessed April 17, 2026.
  27. FES-PET for breast cancer. Society of Nuclear Medicine & Molecular Imaging. https://snmmi.org/Patients/Patients/Procedures/FES-PET-for-Breast-Cancer.aspx. Accessed May 8, 2026.
  28. Member institutions. Alliance for Clinical Trials in Oncology. https://www.allianceforclinicaltrialsinoncology.org/main/public/standard.xhtml?path=%2FPublic%2FInstitutions. Accessed April 17, 2026.