Clinical trials Below are current clinical trials.6 studies in Thoracic Surgery (open studies only). Filter this list of studies by location, status and more. Mayo Clinic Upper Digestive Disease Survey Rochester, Minn. The Mayo Clinic Upper Digestive Disease Survey has been created in order to have a consistent evaluation tools for patients undergoing esophageal reconstruction or treatment or patients that are experiencing an upper digestive disease in order to standardize and validate outcome measures. Data will be used to establish the validation of the questionnaires/survey. Data will also lead to the establishment of “normal” or expected scores for patients undergoing each type of esophagectomy procedure and for upper digestive diseases. Data will contribute to creating treatment algorithms for symptom management for upper digestive diseases and for post-operative complications and symptoms as well as contribute to pre-operative education. A Study to Collect Thoracic Specimens to Develop a Thoracic Specimen Registry Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The primary objective of this proposal is to develop a Thoracic Specimen Registry at Mayo Clinic. The purpose of the registry will be to support ongoing research in the etiology, early diagnosis, clinical management, and prognosis of lung cancer and other cancers and diseases of the thorax by developing a complete repository of specimens from patients with thoracic disease including but not limited to suspected lung cancer, mediastinal and pleural tumors and from patients at a very high risk of developing other thoracic cancers or other thoracic diseases. A Study of the Making and Storage of a Bank of Special Stem Cells for Use in Future Research and the Growth of New Cells Jacksonville, Fla., Rochester, Minn., Scottsdale/Phoenix, Ariz. The purpose of this study is the growing and storage of stem cells, made using the tissue samples of patients and others. As new technologies develop, these cells may be able to be grown into new cells to replace those damaged by disease or injury. A Study to Evaluate Thymoma Recurrence Rochester, Minn. The purpose of this study is to evaluate thymoma recurrence rates in patients who underwent thymectomy. RLY-2608-201-Ph2 Study Of RLY-2608 In PROS And PIK3CA Driven Malformations Rochester, Minn. The purpose of this study is to compare the efficacy and safety of RLY-2608 versus placebo in adult, adolescent, and pediatric participants with PROS and malformations driven by PIK3CA mutations, which is preceded by a dose selection and basket design with exploratory single-arm cohorts for various subpopulations of participants. A Study to Establish a Pediatric Spine Registry Rochester, Minn., Minneapolis, Minn. The purpose of this study is to collect data about patients with chest wall and spinal deformities to develop a multicenter registry. This will speed the pace of medical advancement and treatment recommendations for these conditions. Request an appointment Expertise & rankingsResearch Nov. 20, 2025 Share on: FacebookTwitter Thoracic SurgeryDepartmenthomeSectionsOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsClinical trialsResearchCosts & insuranceReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an AppointmentOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsClinical trialsResearchCosts & insuranceReferrals ORG-20380885 Medical Departments & Centers Thoracic Surgery