Clinical trials Below are current clinical trials.23 studies in Spine Care (open studies only). Filter this list of studies by location, status and more. Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery Rochester, Minn. Postoperative urinary retention is a frequent complication of spinal surgeries and impacts a large portion of this population which results in increased morbidity as a result of increased number of catheterizations, urinary tract infections (UTIs) and prolonged hospital stays. With the addition of Tamsulosin, the investigators would anticipate a reduction in the incidence and duration of postoperative urinary retention and therefore a reduction in morbidity related to treatment of urinary retention as well as shortened hospital stays. A Study to Evaluate the Safety and Effectiveness of Adherus™ AutoSpray and Adherus™ AutoSpray ET Dural Sealant Rochester, Minn., Jacksonville, Fla. The purpose of this study is to evaluate the safety and effectiveness of Adherus Dural Sealant when used in conjunction with standard methods of dural repair in spinal procedures. This trial uses the commercially available DuraSeal Exact (P080013b) as an active control. The trial is designed to demonstrate non-inferiority of Adherus Dural Sealant to DuraSeal Exact. Subjects who have consented to participate in this study prior to undergoing spinal surgery and experience a durotomy, will be considered for study enrollment. A Study to Evaluate Performance Outcomes Following Interventional Treatment of Axial Low Back Pain Jacksonville, Fla. The purpose of this study is to determine if intra-articular lumbar facet and sacroiliac joint injections, or lumbar radiofrequency ablation (RFA) are effective in improving 1) patient-reported measures of pain, function and quality of life; 2) capacity; and 3) performance as measured by change in activity counts. Secondarily, the value of measuring capacity and performance following diagnostic medial branch blocks as a predictor of successful outcomes after lumbar RFA will be explored. A Study to Create a Registry of Non-Fusion Spinal Deformity Correction in Adolescent Idiopathic Scoliosis Rochester, Minn., Minneapolis, Minn. The primary purpose of this study is to evaluate the effectiveness of non-fusion surgical treatment of Spinal Deformity Correction in Adolescent Idiopathic Scoliosis. The Post Approval Study (PAS) is gathering data on the Tether device and it's efficacy and safety. A Study to Evaluate Awake vs. Asleep Spine Surgery Jacksonville, Fla. Patients undergoing spine lumbar surgery will be asked to perform short exams/questionnaires aimed at determining cognitive function, quality of life, health outcomes twice post surgery with a baseline performance prior to surgery. Primary Tumor Research and Outcome Network (PTRON) Registry Rochester, Minn. The purpose of this registry is to collect clinical, diagnostic, and therapeutic data specific for primary spinal column tumor patients, and evaluate it to understand the predictive factors which influence survival, local recurrence, adverse events, perioperative morbidity, and health related quality of life. Transforaminal Lumbar Interbody Fusion (TLIF) Rochester, Minn. The purpose of this study is to evaluate the safety and effectiveness of the investigational treatment compared to the control, and obtain indication expansion for Infuse™ use in one and two level TLIFprocedures. Human Blood and Tissues Repository for Neuroscience Research Jacksonville, Fla. The purpose of this study is to collect adult human blood, cerebrospinal fluid, brain, and spine tissues/fluids at time of surgery in order to conduct future studies of the cellular mechanisms of tissue invasion utilized by brain and spine tumors of the central nervous system (CNS). A Study of the Effect of Treatment on Activity and Muscle Function in Pediatric Patients with Scoliosis Rochester, Minn. This study will explore the relationship between skeletal muscle and physical activity in scoliosis patients to provide insight into both the etiology of scoliosis and possible ways to mitigate the potential harm of treatment. Study to Evaluate the Utility, Safety, Effectiveness, and Cost of Physical Therapy on Elective Spine Surgery Patients Jacksonville, Fla. The purpose of this study is to evaluate the utility, safety, effectiveness, and cost of physical therapy on elective spine surgery patients. Pagination Clinical studies Go to page 11 Go to page 22 Go to page 33 NextNext Page Request an appointment Locations, travel & lodgingResearch June 24, 2023 Share on: FacebookTwitter Spine CareSectionsOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsLocations, travel & lodgingClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an AppointmentOverviewTests & proceduresConditions treatedDoctorsExpertise & rankingsLocations, travel & lodgingClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20423957 Medical Departments & Centers Spine Care