Chest Pain and Coronary Physiology Clinic in Minnesota Overview

Staff in the Chest Pain and Coronary Physiology Clinic at Mayo Clinic treats people with challenging chest pain syndromes. For many people, chest pain (angina) is an acute, life-threatening situation. But for those who have survived one or more heart attacks or who have other heart conditions, chest pain can be a chronic disease. The Department of Cardiovascular Medicine at Mayo Clinic's campus in Minnesota offers experienced staff trained in evaluating and treating people with chest pain.

Staff in the Chest Pain and Coronary Physiology Clinic helps to meet the needs of people who have chest pain who can't be treated with standard approaches. The team has experience evaluating and treating people with undiagnosed, complex or unresolved conditions. Staff uses the most current diagnostic tools and participates in clinical trials.

Doctors in the Chest Pain and Coronary Physiology Clinic work together as a multidisciplinary team with doctors trained in heart and blood vessel conditions (cardiologists), gastrointestinal medicine, pain and anesthesia, vascular medicine, and women's health to diagnose and treat chronic chest pain. These specialists collaborate to diagnose your condition and determine the most appropriate treatment for your condition.

Conditions treated

You may be evaluated and treated in the Chest Pain and Coronary Physiology Clinic if:

  • You have coronary artery disease, or you have normal coronary arteries and experience atypical chest pain.
  • You have had a previous heart attack, coronary angioplasty or stents, or coronary bypass surgery and continue to have chest pain despite medical management.
  • You have a complex cardiac history or known coronary artery disease and no longer can be treated with conventional angioplasty or cardiac surgery.


Your evaluation in the Chest Pain and Coronary Physiology Clinic may involve:

  • Comprehensive evaluation and testing. A comprehensive evaluation may include blood tests and other tests, including an electrocardiogram (ECG), chest X-ray, echocardiogram, angiogram or stress testing. Novel tests for vascular function and mental stress may also be included in your evaluation.
  • Patient education. A health care professional will discuss with you how to make healthy lifestyle changes to help prevent or slow the progression of heart disease. Depending on your unique needs, he or she may offer recommendations regarding blood pressure measurement and control, a personalized exercise prescription, a healthy eating plan, advice about how to stop smoking, and stress management techniques.
  • Risk assessment and management. You'll complete an extensive health history to pinpoint individual risk factors for heart disease and for other chest pain-related diseases. You may also be referred to the Cardiovascular Health Clinic.
  • Treatment options. You may be treated with medications, surgery and other therapeutic options including spinal cord stimulation and enhanced external counterpulsation.

Continuity of care

Continuity of care is important because you represent a complex system of organs and functions that are best viewed by a team of experts working together from a single, complete and reliable base of information.

Mayo Clinic maintains a single electronic medical record that follows you from appointment to appointment. Each doctor works from the same medical record, which is continuously updated throughout the course of your care, including thorough follow-up care. Following diagnosis, you can continue to receive follow-up care in the Chest Pain and Coronary Physiology Clinic.


Doctors in the Chest Pain and Coronary Physiology Clinic conduct clinical research to better understand chest pain and develop new treatment options. Current research covers the full range of diagnostic and treatment advances in coronary artery disease, from new medications to the genetics of the disease. You may have the opportunity to participate in clinical trials. Learn more about research in the Cardiovascular Research Center.


You may be referred by your primary doctor, or you may make an appointment without a referral.