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Jennifer Whitwell, Ph.D.

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Publications

  1. Lavrova A, Pham NTT, Reid RI, Boeve BF, Knopman DS, Petersen RC, Nguyen AT, Ross Reichard R, Dickson DW, Jack CR Jr, Whitwell JL, Josephs KA. Relation of Alzheimer's disease-related TDP-43 proteinopathy to metrics from diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI). Neurobiol Aging. 2025 Jun; 150:97-108 Epub 2025 Mar 08
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  2. Singh-Reilly N, Pham NTT, Graff-Radford J, Machulda MM, Spychalla AJ, Senjem ML, Petersen RC, Lowe VJ, Boeve BF, Jack CR Jr, Josephs KA, Kantarci K, Whitwell JL. White matter hyperintensities in dementia with lewy bodies and posterior cortical atrophy. Neurobiol Aging. 2025 Jun; 150:44-52 Epub 2025 Mar 03
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  3. Shir D, Lee N, McCarter SJ, Ramanan VK, Botha H, Knopman DS, Petersen RC, Boeve BF, Day GS, Graff-Radford NR, Jones DT, Murray ME, Nguyen AT, Reichard RR, Dickson DW, Tajfirouz D, Machulda MM, Whitwell JL, Josephs KA, Graff-Radford J. Longitudinal Evolution of Posterior Cortical Atrophy: Diagnostic Delays, Overlapping Phenotypes, and Clinical Outcomes. Neurology. 2025 May 13; 104 (9):e213559 Epub 2025 Apr 08
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  4. Pottier C, Kucukali F, Baker M, Batzler A, Jenkins GD, van Blitterswijk M, Vicente CT, De Coster W, Wynants S, Van de Walle P, Ross OA, Murray ME, Faura J, Haggarty SJ, van Rooij JG, Mol MO, Hsiung GR, Graff C, Oijerstedt L, Neumann M, Asmann Y, McDonnell SK, Baheti S, Josephs KA, Whitwell JL, Bieniek KF, Forsberg L, Heuer H, Lago AL, Geier EG, Yokoyama JS, Oddi AP, Flanagan M, Mao Q, Hodges JR, Kwok JB, Domoto-Reilly K, Synofzik M, Wilke C, Onyike C, Dickerson BC, Evers BM, Dugger BN, Munoz DG, Keith J, Zinman L, Rogaeva E, Suh E, Gefen T, Geula C, Weintraub S, Diehl-Schmid J, Farlow MR, Edbauer D, Woodruff BK, Caselli RJ, Donker Kaat LL, Huey ED, Reiman EM, Mead S, King A, Roeber S, Nana AL, Ertekin-Taner N, Knopman DS, Petersen RC, Petrucelli L, Uitti RJ, Wszolek ZK, Ramos EM, Grinberg LT, Tempini MLG, Rosen HJ, Spina S, Piguet O, Grossman M, Trojanowski JQ, Keene CD, Jin LW, Prudlo J, Geschwind DH, Rissman RA, Cruchaga C, Ghetti B, Halliday GM, Beach TG, Serrano GE, Arzberger T, Herms J, Boxer AL, Honig LS, Vonsattel JP, Lopez OL, Kofler J, White CL 3rd, Gearing M, Glass J, Rohrer JD, Irwin DJ, Lee EB, Van Deerlin V, Castellani R, Mesulam MM, Tartaglia MC, Finger EC, Troakes C, Al-Sarraj S, Dalgard CL, Miller BL, Seelaar H, Graff-Radford NR, Boeve BF, Mackenzie IR, van Swieten JC, Seeley WW, Sleegers K, Dickson DW, Biernacka JM, Rademakers R. Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing. Nat Commun. 2025 Apr 25; 16 (1):3914
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  5. Meade G, Pham NTT, Boland SM, Clark HM, Duffy JR, Whitwell JL, Botha H, Josephs KA, Utianski RL. Dysphagia and Mortality Risk in Individuals With Primary Progressive Apraxia of Speech. Ann Clin Transl Neurol. 2025 Apr 24 [Epub ahead of print]
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  6. Singh-Reilly N, Graff-Radford J, Li D, Mielke MM, Machulda MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Abeta(42/40) and p-tau 181 as disease biomarkers in atypical Alzheimer's disease. J Alzheimers Dis. 2025 Apr 23; 13872877251333450 [Epub ahead of print]
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  7. Clark HM, Stierwalt JA, Meade G, Ali F, Stephens Y, Botha H, Tosakulwong N, Weigand S, Josephs KA, Whitwell JL. Tongue strength in progressive supranuclear palsy. Parkinsonism Relat Disord. 2025 Apr 14; 135:107839 [Epub ahead of print]
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  8. Kumar M, Brewer B, Ali F, Clark H, Stierwalt J, Stephens Y, Savica R, Ahlskog J, Whitwell J, Josephs K. Evaluating the Clinical Homogeneity of the Progressive Supranuclear Palsy Richardson Syndrome (P1-5.024). Neurology. 2025 Apr 8; 104 (7_Supplement_1):1575 Epub 2025 Apr 07
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  9. Fu M, Gunter J, Satoh R, Gatto R, Ali F, Clark HM, Stierwalt J, Machulda M, Stephens YC, Youssef H, Pham NTT, Jack C, Lowe V, Josephs K, Whitwell J. Disproportionately Enlarged Subarachnoid-space Hydrocephalus and Progressive Supranuclear Palsy (P1-5.023). Neurology. 2025 Apr 8; 104 (7_Supplement_1):1786 Epub 2025 Apr 07
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  10. Utianski RL, Meade G, Meyer MJ, Duffy JR, Clark HM, Whitwell JL, Josephs KA, Poling GL. Testing Feasibility of a Self-Administered Hearing Test for Patients With Progressive Apraxia of Speech and Aphasia. Am J Audiol. 2025 Mar 3; 34 (1):220-226 Epub 2025 Feb 18
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  11. Ghirelli A, Goodrich AW, Stephens YC, Graff-Radford J, Ali F, Machulda MM, Schwarz CG, Senjem ML, Agosta F, Filippi M, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Relationships between hypometabolism and both beta-amyloid and tau PET in corticobasal syndrome. Alzheimers Dement. 2025 Mar; 21 (3):e70018
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  12. Costa F, Gatto RG, Pham NTT, Ali F, Clark HM, Stierwalt J, Machulda MM, Agosta F, Filippi M, Josephs KA, Whitwell JL. Longitudinal assessment of white matter alterations in progressive supranuclear palsy variants using diffusion tractography. Parkinsonism Relat Disord. 2025 Mar; 132:107272 Epub 2025 Jan 10
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  13. Youssef H, Gatto RG, Pham NTT, Jones D, Petersen RC, Machulda MM, Whitwell JL, Josephs KA. Multiple Neuropathologies Underly Hippocampal Subfield Atrophy in a Case With a Slowly Progressive Amnestic Syndrome: Challenging the Notion of Pure LATE-NC. Neuropathology. 2025 Feb 20 [Epub ahead of print]
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  14. Carlos AF, Weigand SD, Pham NTT, Petersen RC, Jack CR Jr, Dickson DW, Whitwell JL, Josephs KA. White matter hyperintensities and TDP-43 pathology in Alzheimer's disease. Alzheimers Dement. 2025 Feb; 21 (2):ealz14516 Epub 2025 Jan 17
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  15. Tetzloff KA, Meade G, Duffy JR, Clark HM, Botha H, Josephs KA, Whitwell JL, Utianski RL. Word Count Matters: Features of Written Language Production in Progressive Apraxia of Speech with and without Agrammatism. Folia Phoniatr Logop. 2025 Jan 17; 1-9 [Epub ahead of print]
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  16. Sintini I, Ali F, Stephens Y, Clark HM, Stierwalt JA, Machulda MM, Satoh R, Josephs KA, Whitwell JL. Functional connectivity abnormalities in clinical variants of progressive supranuclear palsy. Neuroimage Clin. 2025; 45:103727 Epub 2024 Dec 17
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  17. Meade G, Pham NTT, Clark HM, Duffy JR, Whitwell JL, Josephs KA, Utianski RL. Progression of Motor Speech Function in Speakers With Primary Progressive Apraxia of Speech. J Speech Lang Hear Res. 2024 Dec 9; 67 (12):4651-4662 Epub 2024 Nov 15
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  18. Lavrova A, Satoh R, Pham NTT, Nguyen A, Jack CR Jr, Petersen RC, Ross RR, Dickson DW, Lowe VJ, Whitwell JL, Josephs KA. Investigating the feasibility of (18)F-flortaucipir PET imaging in the antemortem diagnosis of primary age-related tauopathy (PART): An observational imaging-pathological study. Alzheimers Dement. 2024 Dec; 20 (12):8605-8614 Epub 2024 Oct 17
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  19. Utianski RL, Meade G, Duffy JR, Clark HM, Botha H, Whitwell JL, Josephs KA. Dementia Care Research and Psychosocial Factors. Alzheimers Dement. 2024 Dec; 20 Suppl 4:e084546
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  20. Boots EA, Broeren MJ, Ali F, Clark HM, Stierwalt JAG, Botha H, Stephens YC, Josephs KA, Whitwell JL, Machulda MM, Stricker NH. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e085992
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  21. Boots EA, Broeren MJ, Ali F, Clark HM, Stierwalt JAG, Botha H, Stephens YC, Josephs KA, Whitwell JL, Machulda MM, Stricker NH. Technology and Dementia Preconference. Alzheimers Dement. 2024 Dec; 20 Suppl 10:e094208
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  22. Singh NA, Alnobani A, Graff-Radford J, Machulda MM, Mielke MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Kanekiyo T, Josephs KA, Whitwell JL. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e094001
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  23. Youssef H, Gatto RG, Pham NTT, Petersen RC, Machulda MM, Reichard RR, Dickson DW, Jack CR Jr, Whitwell JL, Josephs KA. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093812
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  24. Youssef H, Gatto RG, Pham NTT, Petersen RC, Dickson DW, Petrucelli L, Whitwell JL, Prudencio M, Josephs KA. Alzheimer's Imaging Consortium. Alzheimers Dement. 2024 Dec; 20 Suppl 9:e093847
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  25. Singh NA, Alnobani A, Graff-Radford J, Machulda MM, Mielke MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Kanekiyo T, Josephs KA, Whitwell JL. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e091767
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  26. Singh NA, Graff-Radford J, Li D, Mielke MM, Machulda MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e091571
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  27. Youssef H, Gatto RG, Pham NTT, Petersen RC, Dickson DW, Petrucelli L, Whitwell JL, Prudencio M, Josephs KA. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e089704
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  28. Youssef H, Gatto RG, Pham NTT, Petersen RC, Machulda MM, Reichard RR, Dickson DW, Jack CR Jr, Whitwell JL, Josephs KA. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e089174
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  29. Sintini I, Ali F, Stephens YC, Clark HM, Stierwalt JAG, Josephs KA, Whitwell JL. Biomarkers. Alzheimers Dement. 2024 Dec; 20 Suppl 2:e085783
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  30. Gatto RG, Hossam Y, Reichard RR, Lowe VJ, Whitwell JL, Josephs KA. Microscopy assessment of a fluorescence [(18)F] flortaucipir analog (T726) shows neuropathological overlap with 3R and 4R tau lesions. Alzheimers Dement. 2024 Dec; 20 (12):8758-8768 Epub 2024 Oct 22
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  31. Blazek AM, Meade G, Jackson LM, Gavrilova R, Stierwalt J, Martinez-Thompson JM, Duffy JR, Clark H, Machulda MM, Whitwell JL, Josephs KA, Utianski RL, Botha H. Progressive Apraxia of Speech as a Manifestation of Spinocerebellar Ataxia 2: Case Report. Neurol Genet. 2024 Dec; 10 (6):e200202 Epub 2024 Nov 01
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  32. Sekiya H, Satoh R, Ali F, Dickson DW, Whitwell JL, Josephs KA. Utilizing quantitative susceptibility mapping to differentiate primary lateral sclerosis from progressive supranuclear palsy: A case report. Neuropathology. 2024 Nov 18 [Epub ahead of print]
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  33. Watanabe H, Duffy JR, Clark H, Machulda MM, Graff-Radford J, Thu Pham NT, Dickson DW, Lowe VJ, Whitwell JL, Josephs KA. Primary Progressive Aphasia Lacking Core Features of Nonfluent and Semantic Variants: Clinical, Neuroimaging, and Neuropathologic Features. Neurology. 2024 Nov 12; 103 (9):e209924 Epub 2024 Oct 08
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  34. Coburn RP, Graff-Radford J, Machulda MM, Schwarz CG, Lowe VJ, Jones DT, Jack CR Jr, Josephs KA, Whitwell JL, Botha H. Baseline multimodal imaging to predict longitudinal clinical decline in atypical Alzheimer's disease. Cortex. 2024 Nov; 180:18-34 Epub 2024 Sept 11
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  35. Badihian N, Tosakulwong N, Weigand SD, Ali F, Clark HM, Stierwalt J, Botha H, Savica R, Dickson DW, Whitwell JL, Josephs KA. Relationships between regional burden of tau pathology and age at death and disease duration in PSP. Parkinsonism Relat Disord. 2024 Oct; 127:107109 Epub 2024 Aug 17
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  36. Tetzloff KA, Wiepert D, Botha H, Duffy JR, Clark HM, Whitwell JL, Josephs KA, Utianski RL. Automatic Speech Recognition in Primary Progressive Apraxia of Speech. J Speech Lang Hear Res. 2024 Sep 12; 67 (9):2964-2976 Epub 2024 Aug 06
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  37. Spinelli EG, Ghirelli A, Bottale I, Basaia S, Canu E, Castelnovo V, Volonte MA, Galantucci S, Magnani G, Caso F, Cecchetti G, Caroppo P, Prioni S, Villa C, Josephs KA, Whitwell JL, Filippi M, Agosta F. Stepwise Functional Brain Architecture Correlates with Atrophy in Progressive Supranuclear Palsy. Mov Disord. 2024 Sep; 39 (9):1493-1503 Epub 2024 June 17
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  38. Garcia-Guaqueta DP, Ghayal NB, Lowe VJ, Dickson DW, Whitwell JL, Josephs KA. Patterns of glucose hypometabolism can help differentiate FTLD-FET from other types of FTLD. J Neurol. 2024 Sep; 271 (9):6264-6273 Epub 2024 Aug 01
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  39. Garcia-Guaqueta DP, Botha H, Utianski RL, Duffy JR, Clark H, Meade G, Machulda MM, Dickson DW, Pham NTT, Whitwell JL, Josephs KA. Clinicopathologic and Neuroimaging Correlations of Nonverbal Oral Apraxia in Patients With Neurodegenerative Disease. Neurology. 2024 Aug 27; 103 (4):e209717 Epub 2024 July 30
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  40. Turcano P, Whitwell JL, Duffy JR, Machulda MM, Mullan A, Josephs KA, Savica R. Incidence of Primary Progressive Apraxia of Speech and Primary Progressive Aphasia in Olmsted County, MN, 2011-2022. Neurology. 2024 Aug 27; 103 (4):e209693 Epub 2024 July 30
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  41. Shir D, Corriveau-Lecavalier N, Bermudez Noguera C, Barnard L, Pham NTT, Botha H, Duffy JR, Clark HM, Utianski RL, Knopman DS, Petersen RC, Boeve BF, Murray ME, Nguyen AT, Reichard RR, Dickson DW, Day GS, Kremers WK, Graff-Radford NR, Jones DT, Machulda MM, Fields JA, Whitwell JL, Josephs KA, Graff-Radford J. Clinicoradiological and neuropathological evaluation of primary progressive aphasia. J Neurol Neurosurg Psychiatry. 2024 Aug 16; 95 (9):812-821
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  42. Amrami A, Singh NA, Ali F, Pham NTT, Stephens YC, Josephs KA, Whitwell JL. Clinical Utility of Tectal Plate Measurements on Magnetic Resonance Imaging in Progressive Supranuclear Palsy. Mov Disord. 2024 Aug; 39 (8):1402-1407 Epub 2024 Apr 08
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  43. Badihian N, Gatto RG, Satoh R, Ali F, Clark HM, Pham NTT, Whitwell JL, Josephs KA. Clinical and neuroimaging characteristics of primary lateral sclerosis with overlapping features of progressive supranuclear palsy. Eur J Neurol. 2024 Aug; 31 (8):e16320 Epub 2024 Apr 30
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  44. Meade G, Thu Pham NT, Schwarz CG, Clark HM, Duffy JR, Senjem ML, Lowe V, Botha H, Whitwell JL, Josephs KA, Utianski RL. The yes-no reversal phenomenon in patients with primary progressive apraxia of speech. Cortex. 2024 Aug; 177:28-36 Epub 2024 May 04
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  45. Garcia-Guaqueta DP, Stephens YC, Ali F, Utianski RL, Duffy JR, Clark HM, Thu Pham NT, Machulda MM, Lowe VJ, Dickson DW, Whitwell JL, Josephs KA. Comparing classic-onset corticobasal syndrome to speech/language-onset corticobasal syndrome. Parkinsonism Relat Disord. 2024 Aug; 125:107025 Epub 2024 June 03
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  46. Ulugut H, Bertoux M, Younes K, Montembeault M, Fumagalli GG, Samanci B, Illan-Gala I, Kuchcinski G, Leroy M, Thompson JC, Kobylecki C, Santillo AF, Englund E, Waldo ML, Riedl L, Van den Stock J, Vandenbulcke M, Vandenberghe R, Laforce R Jr, Ducharme S, Pressman PS, Caramelli P, de Souza LC, Takada LT, Gurvit H, Hansson O, Diehl-Schmid J, Galimberti D, Pasquier F, Miller BL, Scheltens P, Ossenkoppele R, van der Flier WM, Barkhof F, Fox NC, Sturm VE, Miyagawa T, Whitwell JL, Boeve B, Rohrer JD, Gorno-Tempini ML, Josephs KA, Snowden J, Warren JD, Rankin KP, Pijnenburg YAL, International rtvFTD Working Group. Clinical recognition of frontotemporal dementia with right anterior temporal predominance: A multicenter retrospective cohort study. Alzheimers Dement. 2024 Aug; 20 (8):5647-5661 Epub 2024 July 10
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  47. Whitwell JL, Laureys S. Advances in Understanding Brain Connectivity. Brain Connect 2024 Aug; 14 (6):305-306 Epub 2024 July 30
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  48. Josephs KA, Tosakulwong N, Weigand SD, Graff-Radford J, Schwarz CG, Senjem ML, Machulda MM, Kantarci K, Knopman DS, Nguyen A, Reichard RR, Dickson DW, Petersen RC, Lowe VJ, Jack CR Jr, Whitwell JL. Flortaucipir PET uncovers relationships between tau and amyloid-beta in primary age-related tauopathy and Alzheimer's disease. Sci Transl Med. 2024 Jul 24; 16 (757):eado8076 Epub 2024 July 24
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  49. Meade G, Machulda MM, Clark HM, Duffy JR, Botha H, Whitwell JL, Josephs KA, Utianski RL. Identifying and Addressing Functional Communication Challenges in Patients With Behavioral Variant Frontotemporal Dementia. Am J Speech Lang Pathol. 2024 Jul 3; 33 (4):1573-1589 Epub 2024 June 06
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  50. Garcia-Guaqueta DP, Botha H, Utianski RL, Duffy JR, Clark HM, Goodrich AW, Pham NTT, Machulda MM, Baker M, Rademakers R, Whitwell JL, Josephs KA. Progression to corticobasal syndrome: a longitudinal study of patients with nonfluent primary progressive aphasia and primary progressive apraxia of speech. J Neurol. 2024 Jul; 271 (7):4168-4179 Epub 2024 Apr 07
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  51. Lavrova A, Pham NTT, Vernon CJ, Carlos AF, Petersen RC, Dickson DW, Lowe VJ, Jack CR Jr, Whitwell JL, Josephs KA. A multimodal clinical diagnostic approach using MRI and (18)F-FDG-PET for antemortem diagnosis of TDP-43 in cases with low-intermediate Alzheimer's disease neuropathologic changes and primary age-related tauopathy. J Neurol. 2024 Jul; 271 (7):4105-4118 Epub 2024 Apr 05
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  52. Robinson CG, Goodrich AW, Weigand SD, Pham NTT, Carlos AF, Buciuc M, Murray ME, Nguyen AT, Reichard RR, Knopman DS, Petersen RC, Dickson DW, Utianski RL, Whitwell JL, Josephs KA, Machulda MM. Determinants of confrontation naming deficits on the Boston Naming Test associated with transactive response DNA-binding protein 43 pathology. J Int Neuropsychol Soc. 2024 Jul; 30 (6):575-583 Epub 2024 Mar 25
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  53. Black JA, Pham NTT, Ali F, Machulda MM, Lowe VJ, Josephs KA, Whitwell JL. Frontal hypometabolism in the diagnosis of progressive supranuclear palsy clinical variants. J Neurol. 2024 Jul; 271 (7):4267-4280 Epub 2024 Apr 17
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  54. Singh NA, Alnobani A, Graff-Radford J, Machulda MM, Mielke MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Kanekiyo T, Josephs KA, Whitwell JL. Relationships between PET and blood plasma biomarkers in corticobasal syndrome. Alzheimers Dement. 2024 Jul; 20(7):4765-4774. Epub 2024 Jun 17.
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  55. Singh NA, Graff-Radford J, Machulda MM, Carlos AF, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Atypical Alzheimer's disease: new insights into an overlapping spectrum between the language and visual variants. J Neurol. 2024 Jun; 271 (6):3571-3585 Epub 2024 Mar 29
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  56. Laureys S, Raichle M, Friston K, Whitfield-Gabrieli S, Whitwell J, Calhoun V, Douw L, Boly M. A Roundtable Discussion on Brain Connectivity. Brain Connect 2024 Jun; 14 (5):263-273 Epub 2024 June 11
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  57. Gatto RG, Pham NTT, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Lowe VJ, Schwarz CG, Jack CR Jr, Josephs KA, Whitwell JL. Multimodal cross-examination of progressive apraxia of speech by diffusion tensor imaging-based tractography and Tau-PET scans. Hum Brain Mapp. 2024 Jun 1; 45 (8):e26704
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  58. Tetzloff KA, Martin PR, Duffy JR, Utianski RL, Clark HM, Botha H, Machulda MM, Thu Pham NT, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. Longitudinal flortaucipir, metabolism and volume differ between phonetic and prosodic speech apraxia. Brain. 2024 May 3; 147 (5):1696-1709
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  59. Sintini I, Singh NA, Li D, Mielke MM, Machulda MM, Schwarz CG, Senjem ML, Jack CR Jr, Lowe VJ, Graff-Radford J, Josephs KA, Whitwell JL. Plasma glial fibrillary acidic protein in the visual and language variants of Alzheimer's disease. Alzheimers Dement. 2024 May; 20 (5):3679-3686 Epub 2024 Mar 25
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  60. Singh NA, Goodrich AW, Graff-Radford J, Machulda MM, Sintini I, Carlos AF, Robinson CG, Reid RI, Lowe VJ, Jack CR Jr, Petersen RC, Boeve BF, Josephs KA, Kantarci K, Whitwell JL. Altered structural and functional connectivity in Posterior Cortical Atrophy and Dementia with Lewy bodies. Neuroimage. 2024 Apr 15; 290:120564 Epub 2024 Mar 03
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  61. Meade G, Whitwell JL, Dickson DW, Duffy JR, Clark HM, Ahlskog JE, Machulda MM, Josephs KA, Utianski RL. Primary Progressive Apraxia of Speech Caused by TDP-43: A Case Report. Neurol Genet. 2024 Apr; 10 (2):e200134 Epub 2024 Mar 19
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  62. Petroi-Bock D, Clark HM, Stierwalt JAG, Botha H, Ali F, Whitwell JL, Josephs KA. Influences of motor speech impairments on the presentation of dysphagia in progressive supranuclear palsy. Int J Speech Lang Pathol. 2024 Apr; 26 (2):278-288 Epub 2023 June 19
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  63. Tetzloff KA, Duffy JR, Clark HM, Josephs KA, Whitwell JL, Utianski RL. Characterizing Speech Errors Across Primary Progressive Apraxia of Speech Subtypes. J Speech Lang Hear Res. 2024 Mar 11; 67 (3):811-820 Epub 2024 Feb 20
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  64. Gatto RG, Martin PR, Utianski RL, Duffy JR, Clark HM, Botha H, Machulda MM, Josephs KA, Whitwell JL. Diffusion tensor imaging-based multi-fiber tracking reconstructions can regionally differentiate phonetic versus prosodic subtypes of progressive apraxia of speech. Cortex. 2024 Feb; 171:272-286 Epub 2023 Nov 08
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  65. Badihian N, Ali F, Botha H, Savica R, Machulda MM, Clark HM, Stierwalt JAG, Pham NTT, Baker MC, Rademakers R, Lowe V, Whitwell JL, Josephs KA. The MAPT p.E342K and p.R406W mutations are associated with progressive supranuclear palsy with atypical features. Parkinsonism Relat Disord. 2024 Feb; 119:105962 Epub 2023 Dec 17
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  66. Chapleau M, La Joie R, Yong K, Agosta F, Allen IE, Apostolova L, Best J, Boon BDC, Crutch S, Filippi M, Fumagalli GG, Galimberti D, Graff-Radford J, Grinberg LT, Irwin DJ, Josephs KA, Mendez MF, Mendez PC, Migliaccio R, Miller ZA, Montembeault M, Murray ME, Nemes S, Pelak V, Perani D, Phillips J, Pijnenburg Y, Rogalski E, Schott JM, Seeley W, Sullivan AC, Spina S, Tanner J, Walker J, Whitwell JL, Wolk DA, Ossenkoppele R, Rabinovici GD, PCA International Work Group. Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis. Lancet Neurol. 2024 Feb; 23 (2):168-177
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  67. Satoh R, Ali F, Botha H, Lowe VJ, Josephs KA, Whitwell JL. Direct comparison between (18)F-Flortaucipir tau PET and quantitative susceptibility mapping in progressive supranuclear palsy. Neuroimage. 2024 Feb 1; 286:120509 Epub 2024 Jan 04
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  68. Robinson CG, Coleman T, Buciuc M, Singh NA, Pham NTT, Machulda MM, Graff-Radford J, Whitwell JL, Josephs KA. Behavioral and Neuropsychiatric Differences Across Two Atypical Alzheimer's Disease Variants: Logopenic Progressive Aphasia and Posterior Cortical Atrophy. J Alzheimers Dis. 2024; 97 (2):895-908
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  69. Whitwell JL. Atypical clinical variants of Alzheimer's disease: are they really atypical? Front Neurosci. 2024; 18:1352822 Epub 2024 Feb 28
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  70. Sintini I, Corriveau-Lecavalier N, Jones DT, Machulda MM, Gunter JL, Schwarz CG, Botha H, Carlos AF, Kamykowski MG, Singh NA, Petersen RC, Jack CR Jr, Lowe VJ, Graff-Radford J, Josephs KA, Whitwell JL. Longitudinal default mode sub-networks in the language and visual variants of Alzheimer's disease. Brain Commun. 2024; 6 (2):fcae005 Epub 2024 Jan 08
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  71. Orlandi F, Carlos AF, Ali F, Clark HM, Duffy JR, Utianski RL, Botha H, Machulda MM, Stephens YC, Schwarz CG, Senjem ML, Jack CR, Agosta F, Filippi M, Dickson DW, Josephs KA, Whitwell JL. Histologic tau lesions and magnetic resonance imaging biomarkers differ across two progressive supranuclear palsy variants. Brain Commun. 2024; 6 (2):fcae113 Epub 2024 Apr 05
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  72. Carlos AF, Weigand SD, Duffy JR, Clark HM, Utianski RL, Machulda MM, Botha H, Thu Pham NT, Lowe VJ, Schwarz CG, Whitwell JL, Josephs KA. Volumetric analysis of hippocampal subregions and subfields in left and right semantic dementia. Brain Commun. 2024; 6 (2):fcae097 Epub 2024 Mar 25
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  73. Gatto RG, Meade G, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Josephs KA, Whitwell JL. Combined assessment of progressive apraxia of speech brain microstructure by diffusion tensor imaging tractography and multishell neurite orientation dispersion and density imaging. Brain Behav. 2024 Jan; 14 (1):e3346
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  74. Youssef H, Gatto RG, Pham NTT, Petersen RC, Machulda MM, Reichard RR, Dickson DW, Jack CR, Whitwell JL, Josephs KA. TDP-43 Is Associated with Subiculum and Cornu Ammonis 1 Hippocampal Subfield Atrophy in Primary Age-Related Tauopathy. J Alzheimers Dis. 2024; 99 (3):1023-1032
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  238. Krishnan K, Machulda MM, Whitwell JL, Butts AM, Duffy JR, Strand EA, Senjem ML, Spychalla AJ, Jack CR, Lowe VJ, Josephs KA. Varying Degrees of Temporoparietal Hypometabolism on FDG-PET Reveal Amyloid-Positive Logopenic Primary Progressive Aphasia is not a Homogeneous Clinical Entity. J Alzheimers Dis. 2017; 55 (3):1019-1029
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  239. Tsai RM, Lobach I, Bang J, Whitwell JL, Senjem ML, Jack CR Jr, Rosen H, Miller B, Boxer AL, AL-108-231 Investigators. Clinical correlates of longitudinal brain atrophy in progressive supranuclear palsy. Parkinsonism Relat Disord. 2016 Jul; 28:29-35 Epub 2016 Apr 24
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  243. Jung Y, Whitwell JL, Duffy JR, Strand EA, Machulda MM, Senjem ML, Jack CR, Lowe VJ, Josephs KA. Regional beta-amyloid burden does not correlate with cognitive or language deficits in Alzheimer's disease presenting as aphasia. Eur J Neurol. 2016 Feb; 23 (2):313-9 Epub 2015 June 23
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  245. Madhavan A, Schwarz CG, Duffy JR, Strand EA, Machulda MM, Drubach DA, Kantarci K, Przybelski SA, Reid RI, Senjem ML, Gunter JL, Apostolova LG, Lowe VJ, Petersen RC, Jack CR, Josephs KA, Whitwell JL. Characterizing White Matter Tract Degeneration in Syndromic Variants of Alzheimer's Disease: A Diffusion Tensor Imaging Study. J Alzheimers Dis. 2016; 49 (3):633-43
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  250. Botha H, Duffy JR, Whitwell JL, Strand EA, Machulda MM, Schwarz CG, Reid RI, Spychalla AJ, Senjem ML, Jones DT, Lowe V, Jack CR, Josephs KA. Classification and clinicoradiologic features of primary progressive aphasia (PPA) and apraxia of speech. Cortex. 2015 Aug; 69:220-36 Epub 2015 May 27
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  256. Malone IB, Leung KK, Clegg S, Barnes J, Whitwell JL, Ashburner J, Fox NC, Ridgway GR. Accurate automatic estimation of total intracranial volume: a nuisance variable with less nuisance. Neuroimage. 2015 Jan 1; 104:366-72.
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  264. Jung Y, Dickson DW, Murray ME, Whitwell JL, Knopman DS, Boeve BF, Jack CR Jr, Parisi JE, Petersen RC, Josephs KA. TDP-43 in Alzheimer's disease is not associated with clinical FTLD or Parkinsonism. J Neurol. 2014 Jul; 261 (7):1344-8 Epub 2014 Apr 24
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  298. Coon EA, Whitwell JL, Jack CR Jr, Josephs KA. Primary lateral sclerosis as progressive supranuclear palsy: diagnosis by diffusion tensor imaging. Mov Disord. 2012 Jun; 27 (7):903-6 Epub 2012 Apr 19
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  299. Perry DC, Whitwell JL, Boeve BF, Pankratz VS, Knopman DS, Petersen RC, Jack CR Jr, Josephs KA. Voxel-based morphometry in patients with obsessive-compulsive behaviors in behavioral variant frontotemporal dementia. Eur J Neurol. 2012 Jun; 19 (6):911-7 Epub 2012 Jan 28
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  313. Whitwell JL, Josephs KA, Avula R, Tosakulwong N, Weigand SD, Senjem ML, Vemuri P, Jones DT, Gunter JL, Baker M, Wszolek ZK, Knopman DS, Rademakers R, Petersen RC, Boeve BF, Jack CR Jr. Altered functional connectivity in asymptomatic MAPT subjects: a comparison to bvFTD. Neurology. 2011 Aug 30; 77 (9):866-74 Epub 2011 Aug 17
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  314. Whitwell JL, Weigand SD, Gunter JL, Boeve BF, Rademakers R, Baker M, Knopman DS, Wszolek ZK, Petersen RC, Jack CR Jr, Josephs KA. Trajectories of brain and hippocampal atrophy in FTD with mutations in MAPT or GRN. Neurology. 2011 Jul 26; 77 (4):393-8 Epub 2011 July 13
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  315. Whitwell JL, Master AV, Avula R, Kantarci K, Eggers SD, Edmonson HA, Jack CR Jr, Josephs KA. Clinical correlates of white matter tract degeneration in progressive supranuclear palsy. Arch Neurol. 2011 Jun; 68 (6):753-60
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  316. Coon EA, Sorenson EJ, Whitwell JL, Knopman DS, Josephs KA. Predicting survival in frontotemporal dementia with motor neuron disease. Neurology. 2011 May 31; 76 (22):1886-93
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  317. Kouri N, Whitwell JL, Josephs KA, Rademakers R, Dickson DW. Corticobasal degeneration: a pathologically distinct 4R tauopathy. Nat Rev Neurol. 2011 May; 7 (5):263-72 Epub 2011 Apr 12
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  318. Vemuri P, Simon G, Kantarci K, Whitwell JL, Senjem ML, Przybelski SA, Gunter JL, Josephs KA, Knopman DS, Boeve BF, Ferman TJ, Dickson DW, Parisi JE, Petersen RC, Jack CR Jr. Antemortem differential diagnosis of dementia pathology using structural MRI: Differential-STAND. Neuroimage. 2011 Mar 15; 55 (2):522-31 Epub 2010 Dec 31
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  319. Josephs KA, Whitwell JL, Eggers SD, Senjem ML, Jack CR Jr. Gray matter correlates of behavioral severity in progressive supranuclear palsy. Mov Disord. 2011 Feb 15; 26(3):493-8. Epub 2011 Jan 12.
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  320. Josephs KA Jr, Whitwell JL, Weigand SD, Senjem ML, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Jack CR Jr, Petersen RC. Predicting functional decline in behavioural variant frontotemporal dementia. Brain. 2011 Feb; 134 (Pt 2):432-48 Epub 2011 Jan 20
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  321. Boxer AL, Mackenzie IR, Boeve BF, Baker M, Seeley WW, Crook R, Feldman H, Hsiung GY, Rutherford N, Laluz V, Whitwell J, Foti D, McDade E, Molano J, Karydas A, Wojtas A, Goldman J, Mirsky J, Sengdy P, Dearmond S, Miller BL, Rademakers R. Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family. J Neurol Neurosurg Psychiatry. 2011 Feb; 82(2):196-203. Epub 2010 Jun 20.
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  322. Whitwell JL, Vemuri P. Assessing subtle structural changes in Alzheimer's disease patients. Methods Mol Biol. 2011; 711:535-50.
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  323. Whitwell JL, Jack CR Jr, Parisi JE, Senjem ML, Knopman DS, Boeve BF, Rademakers R, Baker M, Petersen RC, Dickson DW, Josephs KA. Does TDP-43 type confer a distinct pattern of atrophy in frontotemporal lobar degeneration? Neurology. 2010 Dec 14; 75 (24):2212-20
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  324. Whitwell JL, Jack CR Jr, Boeve BF, Parisi JE, Ahlskog JE, Drubach DA, Senjem ML, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Imaging correlates of pathology in corticobasal syndrome. Neurology. 2010 Nov 23; 75 (21):1879-87
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  325. Whitwell JL. Progression of atrophy in Alzheimer's disease and related disorders. Neurotox Res. 2010 Nov; 18 (3-4):339-46 Epub 2010 Mar 30
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  326. Kantarci K, Boeve BF, Wszolek ZK, Rademakers R, Whitwell JL, Baker MC, Senjem ML, Samikoglu AR, Knopman DS, Petersen RC, Jack CR Jr. MRS in presymptomatic MAPT mutation carriers: a potential biomarker for tau-mediated pathology. Neurology. 2010 Aug 31; 75 (9):771-8
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  327. Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Petersen RC, Hu WT, Parisi JE, Dickson DW, Jack CR Jr. Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer's disease. Mov Disord. 2010 Jul 15; 25 (9):1246-52
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  328. Josephs KA, Whitwell JL, Parisi JE, Petersen RC, Boeve BF, Jack CR Jr, Dickson DW. Caudate atrophy on MRI is a characteristic feature of FTLD-FUS. Eur J Neurol. 2010 Jul; 17 (7):969-75 Epub 2010 Mar 03
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  329. Josephs KA, Duffy JR, Fossett TR, Strand EA, Claassen DO, Whitwell JL, Peller PJ. Fluorodeoxyglucose F18 positron emission tomography in progressive apraxia of speech and primary progressive aphasia variants. Arch Neurol. 2010 May; 67: (5)596-605.
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  331. Hassan A, Whitwell JL, Boeve BF, Jack CR Jr, Parisi JE, Dickson DW, Josephs KA. Symmetric corticobasal degeneration (S-CBD). Parkinsonism Relat Disord. 2010 Mar; 16 (3):208-14 Epub 2009 Dec 16
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  332. Josephs KA, Whitwell JL, Knopman DS, Boeve BF, Vemuri P, Senjem ML, Parisi JE, Ivnik RJ, Dickson DW, Petersen RC, Jack CR Jr. Two distinct subtypes of right temporal variant frontotemporal dementia. Neurology. 2009 Nov 3; 73 (18):1443-50
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  333. Whitwell JL, Przybelski SA, Weigand SD, Ivnik RJ, Vemuri P, Gunter JL, Senjem ML, Shiung MM, Boeve BF, Knopman DS, Parisi JE, Dickson DW, Petersen RC, Jack CR Jr, Josephs KA. Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: a cluster analysis study. Brain. 2009 Nov; 132 (Pt 11):2932-46 Epub 2009 Sept 17
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  334. Clarkson MJ, Ourselin S, Nielsen C, Leung KK, Barnes J, Whitwell JL, Gunter JL, Hill DL, Weiner MW, Jack CR Jr, Fox NC, Alzheimer's Disease Neuroimaging Initiative. Comparison of phantom and registration scaling corrections using the ADNI cohort. Neuroimage. 2009 Oct 1; 47(4):1506-13. Epub 2009 May 27.
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  335. Whitwell JL, Jack CR Jr, Boeve BF, Senjem ML, Baker M, Ivnik RJ, Knopman DS, Wszolek ZK, Petersen RC, Rademakers R, Josephs KA. Atrophy patterns in IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M MAPT mutations. Neurology. 2009 Sep 29; 73 (13):1058-65
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  336. Whitwell JL. Voxel-based morphometry: an automated technique for assessing structural changes in the brain. J Neurosci. 2009 Aug 5; 29 (31):9661-4
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  337. Kantarci K, Weigand SD, Przybelski SA, Shiung MM, Whitwell JL, Negash S, Knopman DS, Boeve BF, O'Brien PC, Petersen RC, Jack CR Jr. Risk of dementia in MCI: combined effect of cerebrovascular disease, volumetric MRI, and 1H MRS. Neurology. 2009 Apr 28; 72 (17):1519-25
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  338. Whitwell JL, Jack CR Jr, Boeve BF, Senjem ML, Baker M, Rademakers R, Ivnik RJ, Knopman DS, Wszolek ZK, Petersen RC, Josephs KA. Voxel-based morphometry patterns of atrophy in FTLD with mutations in MAPT or PGRN. Neurology. 2009 Mar 3; 72 (9):813-20
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  339. Whitwell JL, Jack CR Jr, Senjem ML, Parisi JE, Boeve BF, Knopman DS, Dickson DW, Petersen RC, Josephs KA. MRI correlates of protein deposition and disease severity in postmortem frontotemporal lobar degeneration. Neurodegener Dis. 2009; 6 (3):106-17 Epub 2009 Mar 19
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  340. Josephs KA, Whitwell JL, Jack CR Jr. Anatomic correlates of stereotypies in frontotemporal lobar degeneration. Neurobiol Aging. 2008 Dec; 29 (12):1859-63 Epub 2007 June 14
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  342. Josephs KA, Whitwell JL, Vemuri P, Senjem ML, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Petersen RC, Jack CR Jr. The anatomic correlate of prosopagnosia in semantic dementia. Neurology. 2008 Nov 11; 71 (20):1628-33
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  344. Vemuri P, Whitwell JL, Kantarci K, Josephs KA, Parisi JE, Shiung MS, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Jack CR Jr. Antemortem MRI based STructural Abnormality iNDex (STAND)-scores correlate with postmortem Braak neurofibrillary tangle stage. Neuroimage. 2008 Aug 15; 42 (2):559-67 Epub 2008 May 20
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  347. Hua X, Leow AD, Lee S, Klunder AD, Toga AW, Lepore N, Chou YY, Brun C, Chiang MC, Barysheva M, Jack CR Jr, Bernstein MA, Britson PJ, Ward CP, Whitwell JL, Borowski B, Fleisher AS, Fox NC, Boyes RG, Barnes J, Harvey D, Kornak J, Schuff N, Boreta L, Alexander GE, Weiner MW, Thompson PM, Alzheimer's Disease Neuroimaging Initiative. 3D characterization of brain atrophy in Alzheimer's disease and mild cognitive impairment using tensor-based morphometry. Neuroimage. 2008 May 15; 41(1):19-34. Epub 2008 Feb 21.
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  348. Josephs KA, Whitwell JL, Knopman DS, Hu WT, Stroh DA, Baker M, Rademakers R, Boeve BF, Parisi JE, Smith GE, Ivnik RJ, Petersen RC, Jack CR Jr, Dickson DW. Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype. Neurology. 2008 May 6; 70 (19 Pt 2):1850-7 Epub 2008 Apr 09
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  349. Ridha BH, Anderson VM, Barnes J, Boyes RG, Price SL, Rossor MN, Whitwell JL, Jenkins L, Black RS, Grundman M, Fox NC. Volumetric MRI and cognitive measures in Alzheimer disease : comparison of markers of progression. J Neurol. 2008 Apr; 255(4):567-74. Epub 2008 Feb 18.
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  350. Josephs KA, Whitwell JL, Parisi JE, Knopman DS, Boeve BF, Geda YE, Jack CR Jr, Petersen RC, Dickson DW. Argyrophilic grains: a distinct disease or an additive pathology? Neurobiol Aging. 2008 Apr; 29 (4):566-73 Epub 2006 Dec 26
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  351. Whitwell JL, Shiung MM, Przybelski SA, Weigand SD, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive impairment. Neurology. 2008 Feb 12; 70 (7):512-20 Epub 2007 Sept 26
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  352. Vemuri P, Gunter JL, Senjem ML, Whitwell JL, Kantarci K, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studies. Neuroimage. 2008 Feb 1; 39 (3):1186-97 Epub 2007 Oct 22
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  353. Josephs KA, Whitwell JL, Dickson DW, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Jack CR Jr. Voxel-based morphometry in autopsy proven PSP and CBD. Neurobiol Aging. 2008 Feb; 29 (2):280-9 Epub 2006 Nov 13
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  354. Whitwell JL, Jack CR Jr, Pankratz VS, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Josephs KA. Rates of brain atrophy over time in autopsy-proven frontotemporal dementia and Alzheimer disease. Neuroimage. 2008 Feb 1; 39 (3):1034-40 Epub 2007 Oct 10
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  355. Josephs KA, Whitwell JL, Ahmed Z, Shiung MM, Weigand SD, Knopman DS, Boeve BF, Parisi JE, Petersen RC, Dickson DW, Jack CR Jr. Beta-amyloid burden is not associated with rates of brain atrophy. Ann Neurol. 2008 Feb; 63 (2):204-12
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  356. Josephs KA, Whitwell JL, Duffy JR, Vanvoorst WA, Strand EA, Hu WT, Boeve BF, Graff-Radford NR, Parisi JE, Knopman DS, Dickson DW, Jack CR Jr, Petersen RC. Progressive aphasia secondary to Alzheimer disease vs FTLD pathology. Neurology. 2008 Jan 1; 70 (1):25-34
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  357. Whitwell JL, Petersen RC, Negash S, Weigand SD, Kantarci K, Ivnik RJ, Knopman DS, Boeve BF, Smith GE, Jack CR Jr. Patterns of atrophy differ among specific subtypes of mild cognitive impairment. Arch Neurol. 2007 Aug; 64 (8):1130-8
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  360. Whitwell JL, Przybelski SA, Weigand SD, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease. Brain. 2007 Jul; 130 (Pt 7):1777-86 Epub 2007 May 28
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  361. Whitwell JL, Jack CR Jr, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Ferman TJ, Dickson DW, Josephs KA. Rates of cerebral atrophy differ in different degenerative pathologies. Brain. 2007 Apr; 130 (Pt 4):1148-58 Epub 2007 Mar 08
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  362. Whitwell JL, Sampson EL, Loy CT, Warren JE, Rossor MN, Fox NC, Warren JD. VBM signatures of abnormal eating behaviours in frontotemporal lobar degeneration. Neuroimage. 2007 Mar; 35(1):207-13. Epub 2007 Jan 19.
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  364. Whitwell JL, Weigand SD, Shiung MM, Boeve BF, Ferman TJ, Smith GE, Knopman DS, Petersen RC, Benarroch EE, Josephs KA, Jack CR Jr. Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease. Brain. 2007 Mar; 130 (Pt 3):708-19 Epub 2007 Jan 31
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  366. Whitwell JL, Josephs KA. Voxel-based morphometry and its application to movement disorders. Parkinsonism Relat Disord. 2007; 13 Suppl 3:S406-16.
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  367. Josephs KA, Whitwell JL, Jack CR, Parisi JE, Dickson DW. Frontotemporal lobar degeneration without lobar atrophy. Arch Neurol. 2006 Nov; 63 (11):1632-8
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  368. Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Tang-Wai DF, Drubach DA, Jack CR Jr, Petersen RC. Visual hallucinations in posterior cortical atrophy. Arch Neurol. 2006 Oct; 63 (10):1427-32
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  369. Barnes J, Whitwell JL, Frost C, Josephs KA, Rossor M, Fox NC. Measurements of the amygdala and hippocampus in pathologically confirmed Alzheimer disease and frontotemporal lobar degeneration. Arch Neurol. 2006 Oct; 63(10):1434-9.
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  370. Schott JM, Frost C, Whitwell JL, Macmanus DG, Boyes RG, Rossor MN, Fox NC. Combining short interval MRI in Alzheimer's disease: Implications for therapeutic trials. J Neurol. 2006 Sep; 253(9):1147-53. Epub 2006 Sep 22.
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  371. Leow AD, Klunder AD, Jack CR Jr, Toga AW, Dale AM, Bernstein MA, Britson PJ, Gunter JL, Ward CP, Whitwell JL, Borowski BJ, Fleisher AS, Fox NC, Harvey D, Kornak J, Schuff N, Studholme C, Alexander GE, Weiner MW, Thompson PM, ADNI Preparatory Phase Study. Longitudinal stability of MRI for mapping brain change using tensor-based morphometry. Neuroimage. 2006 Jun; 31(2):627-40. Epub 2006 Feb 15.
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  372. Josephs KA, Duffy JR, Strand EA, Whitwell JL, Layton KF, Parisi JE, Hauser MF, Witte RJ, Boeve BF, Knopman DS, Dickson DW, Jack CR Jr, Petersen RC. Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech. Brain. 2006 Jun; 129 (Pt 6):1385-98 Epub 2006 Apr 13
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  373. Whitwell JL, Jack CR Jr, Senjem ML, Josephs KA. Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration. Neurology. 2006 Jan 10; 66 (1):102-4
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  374. Josephs KA, Petersen RC, Knopman DS, Boeve BF, Whitwell JL, Duffy JR, Parisi JE, Dickson DW. Clinicopathologic analysis of frontotemporal and corticobasal degenerations and PSP. Neurology. 2006 Jan 10; 66 (1):41-8
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  375. Josephs KA, Whitwell JL, Boeve BF, Shiung MM, Gunter JL, Parisi JE, Dickson DW, Jack CR. Rates of cerebral atrophy in autopsy-confirmed progressive supranuclear palsy. Ann Neurol. 2006 Jan; 59(1):200-3.
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  376. Whitwell JL, Jack CR Jr. Comparisons between Alzheimer disease, frontotemporal lobar degeneration, and normal aging with brain mapping. Top Magn Reson Imaging. 2005 Dec; 16(6):409-25.
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  377. Whitwell JL, Josephs KA, Rossor MN, Stevens JM, Revesz T, Holton JL, Al-Sarraj S, Godbolt AK, Fox NC, Warren JD. Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia. Arch Neurol. 2005 Sep; 62(9):1402-8.
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  378. Josephs KA, Knopman DS, Whitwell JL, Boeve BF, Parisi JE, Petersen RC, Dickson DW. Survival in two variants of tau-negative frontotemporal lobar degeneration: FTLD-U vs FTLD-MND. Neurology. 2005 Aug 23; 65(4):645-7.
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  379. Schott JM, Price SL, Frost C, Whitwell JL, Rossor MN, Fox NC. Measuring atrophy in Alzheimer disease: a serial MRI study over 6 and 12 months. Neurology. 2005 Jul 12; 65(1):119-24.
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  380. Whitwell JL, Sampson EL, Watt HC, Harvey RJ, Rossor MN, Fox NC. A volumetric magnetic resonance imaging study of the amygdala in frontotemporal lobar degeneration and Alzheimer's disease. Dement Geriatr Cogn Disord. 2005; 20(4):238-44. Epub 2005 Aug 05.
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  381. Whitwell JL, Schott JM, Lewis EB, MacManus DG, Fox NC. Using nine degrees-of-freedom registration to correct for changes in voxel size in serial MRI studies. Magn Reson Imaging. 2004 Sep; 22(7):993-9.
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  382. Whitwell JL, Warren JD, Josephs KA, Godbolt AK, Revesz T, Fox NC, Rossor MN. Voxel-based morphometry in tau-positive and tau-negative frontotemporal lobar degenerations. Neurodegener Dis. 2004; 1(4-5):225-30.
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  383. Whitwell JL, Anderson VM, Scahill RI, Rossor MN, Fox NC. Longitudinal patterns of regional change on volumetric MRI in frontotemporal lobar degeneration. Dement Geriatr Cogn Disord. 2004; 17(4):307-10.
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  384. Chan D, Janssen JC, Whitwell JL, Watt HC, Jenkins R, Frost C, Rossor MN, Fox NC. Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study. Lancet. 2003 Oct 4; 362(9390):1121-2.
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  385. Scahill RI, Frost C, Jenkins R, Whitwell JL, Rossor MN, Fox NC. A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging. Arch Neurol. 2003 Jul; 60(7):989-94.
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  386. Whitwell JL, Crum WR, Watt HC, Fox NC. Normalization of cerebral volumes by use of intracranial volume: implications for longitudinal quantitative MR imaging. AJNR Am J Neuroradiol. 2001 Sep; 22(8):1483-9.
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  387. Chan D, Fox NC, Scahill RI, Crum WR, Whitwell JL, Leschziner G, Rossor AM, Stevens JM, Cipolotti L, Rossor MN. Patterns of temporal lobe atrophy in semantic dementia and Alzheimer's disease. Ann Neurol. 2001 Apr; 49(4):433-42.
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