Publications Print Lieve KV, van der Werf C, Kallas D, Denjoy I, Bos JM, Aiba T, Behr ER, van den Berg MP, Bergeman AT, Blom NA, Borggrefe M, Brugada R, Carrillo Mora LM, Chorin E, Crotti L, Davis A, Drago F, Dusi V, Extramiana F, Franciosi S, Giudicessi JR, Gonzalez Llopis FA, Haugaa KH, van den Heuvel F, Horie M, Ingles J, Kammeraad J, Kannankeril PJ, Khan HR, Krahn AD, MacIntyre C, Maltret A, Marjamaa A, Ohno S, Peltenburg PJ, Perez GJ, Probst V, Roberts JD, Robyns T, Rootwelt-Norberg C, Roses I Noguer F, Roston TM, Rydberg A, Sacher F, Sarquella-Brugada G, Schwartz PJ, Semsarian C, Shimizu W, Starling L, Sumitomo N, Skinner JR, Tavacova T, Tfelt-Hansen J, Till JA, Yap SC, Wada Y, Wanguemert F, Zorio E, Ackerman MJ, Leenhardt A, Sanatani S, Tanck MW, Wilde AA. Catecholaminergic polymorphic ventricular tachycardia mediated by ryanodine receptor 2: a validated risk stratification. Eur Heart J. 2026 Sep 2; 47 (33):4606-4617 View PubMed Sardana M, MacIntyre C, Giudicessi JR, Ackerman MJ. Paediatric-to-adult transition in inherited arrhythmia syndromes. Eur Heart J. 2026 Aug 26 [Epub ahead of print] View PubMed Viskin D, Bos JM, Tobert KE, Neves R, MacIntyre CJ, Giudicessi J, Ackerman MJ. Circadian pattern of ventricular fibrillation-terminating shocks among patients with diagnosed and treated congenital long QT syndrome. Heart Rhythm. 2026 Jul 6 Epub 2026 July 06 View PubMed Garmany R, Castrichini M, Neves R, Pereira NL, MacIntyre C, Schneider JW, Ackerman MJ, Giudicessi JR. Age at onset and clinical course of RBM20-mediated cardiomyopathy. Sci Rep. 2025 Mar 28; 15 (1):10716 View PubMed Pinsky AM, Asaki SY, Bains S, Bos JM, Etheridge SP, Giudicessi JR, MacIntyre C, Ackerman MJ. Intersection of arrhythmogenic genetic heart diseases and transgender hormone therapy. JACC: Clinical Electrophysiology. 2025; 11 (11):2516-8 Lampert R, Chung EH, Ackerman MJ, Arroyo AR, Darden D, Deo R, Dolan J, Etheridge SP, Gray BR, Harmon KG, James CA, Kim JH, Krahn AD, La Gerche A, Link MS, MacIntyre C, Mont L, Salerno JC, Shah MJ. 2024 HRS expert consensus statement on arrhythmias in the athlete: Evaluation, treatment, and return to play. Heart Rhythm. 2024 Oct; 21 (10):e151-e252 Epub 2024 May 17 View PubMed Burczak DR, Scott CG, Julakanti RR, Kara Balla A, Swain WH, Ismail K, Geske JB, Killu AM, Deshmukh AJ, MacIntyre CJ, Ommen SR, Nkomo VT, Gersh BJ, Noseworthy PA, Siontis KC. Persistence of left atrial thrombus in patients with hypertrophic cardiomyopathy and atrial fibrillation. J Interv Card Electrophysiol. 2024 Jun; 67 (4):731-738 Epub 2023 Sept 16 View PubMed Carrick RT, De Marco C, Gasperetti A, Bosman LP, Gourraud JB, Trancuccio A, Mazzanti A, Murray B, Pendleton C, Tichnell C, Tandri H, Zeppenfeld K, Wilde AAM, Davies B, Seifer C, Roberts JD, Healey JS, MacIntyre C, Alqarawi W, Tadros R, Cutler MJ, Targetti M, Calo L, Vitali F, Bertini M, Compagnucci P, Casella M, Dello Russo A, Cappelletto C, De Luca A, Stolfo D, Duru F, Jensen HK, Svensson A, Dahlberg P, Hasselberg NE, Di Marco A, Jorda P, Arbelo E, Moreno Weidmann Z, Borowiec K, Deliniere A, Biernacka EK, van Tintelen JP, Platonov PG, Olivotto I, Saguner AM, Haugaa KH, Cox M, Tondo C, Merlo M, Krahn AD, Te Riele ASJM, Wu KC, Calkins H, James CA, Cadrin-Tourigny J. Implantable cardioverter defibrillator use in arrhythmogenic right ventricular cardiomyopathy in North America and Europe. Eur Heart J. 2024 Feb 16; 45 (7):538-548 View PubMed Neves R, Bains S, Bos JM, MacIntyre C, Giudicessi JR, Ackerman MJ. Precision therapy in congenital long QT syndrome. Trends Cardiovasc Med. 2024 Jan; 34 (1):39-47 Epub 2022 June 27 View PubMed Neves R, Tseng AS, Garmany R, Fink AL, McLeod CJ, Cooper LT, MacIntyre CJ, Homb AC, Rosenbaum AN, Bois JP, Abou Ezzeddine OF, Siontis KC, Pereira NL, Ackerman MJ, Giudicessi JR. Cardiac fludeoxyglucose-18 positron emission tomography in genotype-positive arrhythmogenic cardiomyopathy. Int J Cardiol. 2023 Oct 15; 389:131173 Epub 2023 July 08 View PubMed Davies RA, Ladouceur VB, Green MS, Joza J, Juurlink DN, Krahn AD, McMurtry MS, Roberts JD, Roston TM, Sanatani S, Steinberg C, MacIntyre C. The 2023 Canadian Cardiovascular Society Clinical Practice Update on Management of the Patient With a Prolonged QT Interval. Can J Cardiol. 2023 Oct; 39 (10):1285-1301 View PubMed MacIntyre CJ, Ackerman MJ. Personalized Care in Long QT Syndrome: Better Management, More Sports, and Fewer Devices. Card Electrophysiol Clin. 2023 Sep; 15 (3):285-291 Epub 2023 June 09 View PubMed Neves R, Bains S, Bos JM, MacIntyre CJ, Giudicessi JR, Ackerman MJ. Fatal Cardiac Arrhythmias During Electronic Gaming in Patients With Genetically Mediated Heart Diseases. J Am Coll Cardiol. 2023 Aug 15; 82 (7):603-611 View PubMed Boursalie S, MacIntyre C, Sapp JL, Gray C, Abdelwahab A, Gardner M, Lee D, Matheson K, Parkash R. Disparities in Referral and Utilization of Implantable Cardioverter Defibrillators for Primary Prevention of Sudden Cardiac Death. Can J Cardiol. 2023 Jul 7 Epub 2023 July 07 View PubMed Roberts H, Matheson K, Sapp J, Gardner M, Gray C, AbdelWahab A, Lee D, MacIntyre C, Parkash R. Prevalence and management of electrical lead abnormalities in cardiac implantable electronic device leads. Heart Rhythm O2. 2023 Jul; 4 (7):417-426 Epub 2023 May 20 View PubMed Janzen ML, Davies B, Laksman ZWM, Roberts JD, Sanatani S, Steinberg C, Tadros R, Cadrin-Tourigny J, MacIntyre C, Atallah J, Fournier A, Green MS, Hamilton R, Khan HR, Kimber S, White S, Joza J, Makanjee B, Ilhan E, Lee D, Hansom S, Hadjis A, Arbour L, Leather R, Seifer C, Angaran P, Simpson CS, Healey JS, Gardner M, Talajic M, Krahn AD. Management of Inherited Arrhythmia Syndromes: A HiRO Consensus Handbook on Process of Care. CJC Open. 2023 Apr; 5 (4):268-284 Epub 2023 Feb 26 View PubMed Bains S, Neves R, Bos JM, Giudicessi JR, MacIntyre C, Ackerman MJ. Phenotypes of Overdiagnosed Long QT Syndrome. J Am Coll Cardiol. 2023 Feb 7; 81 (5):477-486 View PubMed Wilde AAM, Semsarian C, Marquez MF, Shamloo AS, Ackerman MJ, Ashley EA, Sternick EB, Barajas-Martinez H, Behr ER, Bezzina CR, Breckpot J, Charron P, Chockalingam P, Crotti L, Gollob MH, Lubitz S, Makita N, Ohno S, Ortiz-Genga M, Sacilotto L, Schulze-Bahr E, Shimizu W, Sotoodehnia N, Tadros R, Ware JS, Winlaw DS, Kaufman ES, Aiba T, Bollmann A, Choi JI, Dalal A, Darrieux F, Giudicessi J, Guerchicoff M, Hong K, Krahn AD, MacIntyre C, Mackall JA, Mont L, Napolitano C, Ochoa JP, Peichl P, Pereira AC, Schwartz PJ, Skinner J, Stellbrink C, Tfelt-Hansen J, Deneke T, Document Reviewers//Developed in partnership with and endorsed by the European Heart Rhythm Association (EHRA), a branch of the European Society of Cardiology (ESC), the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS).. European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases. Europace. 2022 Sep 1; 24 (8):1307-1367 View PubMed Wilde AAM, Semsarian C, Marquez MF, Sepehri Shamloo A, Ackerman MJ, Ashley EA, Sternick EB, Barajas-Martinez H, Behr ER, Bezzina CR, Breckpot J, Charron P, Chockalingam P, Crotti L, Gollob MH, Lubitz S, Makita N, Ohno S, Ortiz-Genga M, Sacilotto L, Schulze-Bahr E, Shimizu W, Sotoodehnia N, Tadros R, Ware JS, Winlaw DS, Kaufman ES, Aiba T, Bollmann A, Choi JI, Dalal A, Darrieux F, Giudicessi J, Guerchicoff M, Hong K, Krahn AD, MacIntyre C, Mackall JA, Mont L, Napolitano C, Ochoa JP, Peichl P, Pereira AC, Schwartz PJ, Skinner J, Stellbrink C, Tfelt-Hansen J, Deneke T, Document Reviewers. European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases. Heart Rhythm. 2022 Jul; 19 (7):e1-e60 Epub 2022 Apr 04 View PubMed Alqarawi W, Dewidar O, Tadros R, Roberts JD, Steinberg C, MacIntyre CJ, Laksman ZWM, Green MS, Nair G, Wells G, Krahn AD. Defining idiopathic ventricular fibrillation: A systematic review of diagnostic testing yield in apparently unexplained cardiac arrest. Heart Rhythm. 2021 Jul; 18 (7):1178-1185 Epub 2021 Mar 26 View PubMed Davies B, Roberts JD, Tadros R, Green MS, Healey JS, Simpson CS, Sanatani S, Steinberg C, MacIntyre C, Angaran P, Duff H, Hamilton R, Arbour L, Leather R, Seifer C, Fournier A, Atallah J, Kimber S, Makanjee B, Alqarawi W, Cadrin-Tourigny J, Joza J, McKinney J, Clarke S, Laksman ZWM, Gibbs K, Vuksanovic V, Gardner M, Talajic M, Krahn AD. The Hearts in Rhythm Organization: A Canadian National Cardiogenetics Network. CJC Open. 2020 Nov; 2 (6):652-662 Epub 2020 May 29 View PubMed Sandhu RK, Raj SR, Thiruganasambandamoorthy V, Kaul P, Morillo CA, Krahn AD, Guzman JC, Sheldon RS, Banijamali HS, MacIntyre C, Manlucu J, Seifer C, Sivilotti M, Primary Writing Committee//Secondary Writing Committee. Canadian Cardiovascular Society Clinical Practice Update on the Assessment and Management of Syncope. Can J Cardiol. 2020 Aug; 36 (8):1167-1177 Epub 2020 July 02 View PubMed Zhou S, AbdelWahab A, Horacek BM, MacInnis PJ, Warren JW, Davis JS, Elsokkari I, Lee DC, MacIntyre CJ, Parkash R, Gray CJ, Gardner MJ, Marcoux C, Choudhury R, Trayanova NA, Sapp JL. Prospective Assessment of an Automated Intraprocedural 12-Lead ECG-Based System for Localization of Early Left Ventricular Activation. Circ Arrhythm Electrophysiol. 2020 Jul; 13 (7):e008262 Epub 2020 June 15 View PubMed MacIntyre CJ, Rohatgi RK, Sugrue AM, Bos JM, Ackerman MJ. Intentional nontherapy in long QT syndrome. Heart Rhythm. 2020 Jul; 17 (7):1147-1150 Epub 2020 Feb 24 View PubMed Sapp JL, Alqarawi W, MacIntyre CJ, Tadros R, Steinberg C, Roberts JD, Laksman Z, Healey JS, Krahn AD. Guidance on Minimizing Risk of Drug-Induced Ventricular Arrhythmia During Treatment of COVID-19: A Statement from the Canadian Heart Rhythm Society. Can J Cardiol. 2020 Jun; 36 (6):948-951 Epub 2020 Apr 08 View PubMed Zhou S, Sapp JL, Horacek BM, Warren JW, MacInnis PJ, Davis J, Elsokkari I, Choudhury R, Parkash R, Gray C, Gardner M, MacIntyre CJ, AbdelWahab A. Automated intraprocedural localization of origin of ventricular activation using patient-specific computed tomographic imaging. Heart Rhythm. 2020 Apr; 17 (4):567-575 Epub 2019 Oct 25 View PubMed MacIntyre CJ, Sapp JL, Abdelwahab A, Al-Harbi M, Doucette S, Gray C, Gardner MJ, Parkash R. The Effect of Shock Burden on Heart Failure and Mortality. CJC Open. 2019 Jul; 1 (4):161-167 Epub 2019 June 07 View PubMed Beca B, Sapp JL, Gardner MJ, Gray C, AbdelWahab A, MacIntyre C, Doucette S, Parkash R. Mortality and Heart Failure After Upgrade to Cardiac Resynchronization Therapy. CJC Open. 2019 Mar; 1 (2):93-99 Epub 2019 Mar 06 View PubMed Elsokkari I, Sapp JL, Doucette S, Parkash R, Gray CJ, Gardner MJ, Macintyre C, AbdelWahab AM. Role of contact force in ischemic scar-related ventricular tachycardia ablation; optimal force required and impact of left ventricular access route. J Interv Card Electrophysiol. 2018 Dec; 53 (3):323-331 Epub 2018 June 26 View PubMed Sreetharan S, MacIntyre CJ, Fatah M, Warren AE, Wilson GJ, Hamilton RM. Clinical utility of endomyocardial biopsies in the diagnosis of arrhythmogenic right ventricular cardiomyopathy in children. Pediatr Res. 2018 Oct; 84 (4):552-557 Epub 2018 July 06 View PubMed MacIntyre C, Iwuala C, Parkash R. Cardiac Arrhythmias and Pregnancy. Curr Treat Options Cardiovasc Med. 2018 Jul 11; 20 (8):63 Epub 2018 July 11 View PubMed Styles K, Sapp J Jr, Gardner M, Gray C, Abdelwahab A, MacIntyre C, Gao D, Al-Harbi M, Doucette S, Theriault C, Parkash R. The influence of sex and age on ventricular arrhythmia in a population-based registry. Int J Cardiol. 2017 Oct 1; 244:169-174 Epub 2017 June 13 View PubMed MacIntyre CJ, Sapp JL. Treatment of persistent ventricular tachycardia: Drugs or ablation? Trends Cardiovasc Med. 2017 Oct; 27 (7):506-513 Epub 2017 May 10 View PubMed Weng W, Sapp J, Doucette S, MacIntyre C, Gray C, Gardner M, Abdelwahab A, Parkash R. Benefit of Implantable Cardioverter-Defibrillator Generator Replacement in a Primary Prevention Population-Based Cohort. JACC Clin Electrophysiol. 2017 Oct; 3 (10):1180-1189 Epub 2017 May 31 View PubMed Kumar S, Baldinger SH, Gandjbakhch E, Maury P, Sellal JM, Androulakis AF, Waintraub X, Charron P, Rollin A, Richard P, Stevenson WG, Macintyre CJ, Ho CY, Thompson T, Vohra JK, Kalman JM, Zeppenfeld K, Sacher F, Tedrow UB, Lakdawala NK. Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers. J Am Coll Cardiol. 2016 Nov 29; 68 (21):2299-2307 View PubMed Kumar S, Androulakis AF, Sellal JM, Maury P, Gandjbakhch E, Waintraub X, Rollin A, Richard P, Charron P, Baldinger SH, Macintyre CJ, Koplan BA, John RM, Michaud GF, Zeppenfeld K, Sacher F, Lakdawala NK, Stevenson WG, Tedrow UB. Multicenter Experience With Catheter Ablation for Ventricular Tachycardia in Lamin A/C Cardiomyopathy. Circ Arrhythm Electrophysiol. 2016 Aug; 9 (8) View PubMed MacIntyre C, Lakdawala NK. Management of Atrial Fibrillation in Hypertrophic Cardiomyopathy. Circulation. 2016 May 10; 133 (19):1901-5 View PubMed Alexander KM, Veillet-Chowdhury MR, MacIntyre CJ, Loscalzo J, Bhatt DL. A Shocking Development in a Young Male Athlete With Chest Pain. Circulation. 2016 Feb 23; 133 (8):756-63 View PubMed Macintyre CJ, Sapp JL. Catheter ablation for ventricular tachycardia in structural heart disease. Can J Cardiol. 2014 Feb; 30 (2):244-6 Epub 2013 Nov 20 View PubMed PST-20590339 Home Publications