Publications Print Valerius AR, Webb LM, Thomsen A, Lehrer EJ, Breen WG, Campian JL, Riviere-Cazaux C, Burns TC, Sener U. Review of Novel Surgical, Radiation, and Systemic Therapies and Clinical Trials in Glioblastoma. Int J Mol Sci. 2024 Sep 30; 25 (19) Epub 2024 Sept 30 View PubMed El-Hajj VG, Ghaith AK, Hoang H, Nguyen RH, Al-Saidi NN, Graepel SP, Atallah E, Elmi-Terander A, Lehrer EJ, Brown PD, Bydon M. Impact of proton versus photon adjuvant radiotherapy on overall survival in the management of skull base and spinal chordomas: a National Cancer Database analysis. J Neurosurg. 2024 Aug 23; 1-9 [Epub ahead of print] View PubMed Frechette KM, Breen WG, Brown PD, Sener UT, Webb LM, Routman DM, Laack NN, Mahajan A, Lehrer EJ. Radiotherapy and Systemic Treatment for Leptomeningeal Disease. Biomedicines. 2024 Aug 7; 12 (8) Epub 2024 Aug 07 View PubMed Lehrer EJ, Breen WG, Singh R, Palmer JD, Brown PD, Trifiletti DM, Sheehan JP. Hypofractionated Stereotactic Radiosurgery in the Management of Brain Metastases. Neurosurgery. 2024 Aug 1; 95 (2):253-258 Epub 2024 Mar 21 View PubMed Singh R, Valluri A, Lehrer EJ, Cao Y, Upadhyay R, Trifiletti DM, Lo SS, Redmond KJ, Sahgal A, Nguyen QN, Palmer JD. Clinical Outcomes After Stereotactic Body Radiation Therapy for Nonspinal Bone Metastases: A Systematic Review and Meta-analysis. Int J Radiat Oncol Biol Phys. 2024 Jul 15; 119 (4):1099-1109 Epub 2024 Jan 12 View PubMed Hotca A, Sindhu KK, Lehrer EJ, Hartsell WF, Vargas C, Tsai HK, Chang JH, Apisarnthanarax S, Nichols RC Jr, Chhabra AM, Hasan S, Press RH, Lazarev S, Hajj C, Kabarriti R, Rule WG, Simone CB 2nd, Choi JI. Reirradiation With Proton Therapy for Recurrent Malignancies of the Esophagus and Gastroesophageal Junction: Results of the Proton Collaborative Group Multi-Institutional Prospective Registry Trial. Adv Radiat Oncol. 2024 May; 9 (5):101459 Epub 2024 Feb 06 View PubMed Marvaso G, Jereczek-Fossa BA, Zaffaroni M, Vincini MG, Corrao G, Andratschke N, Balagamwala EH, Bedke J, Blanck O, Capitanio U, Correa RJM, De Meerleer G, Franzese C, Gaeta A, Gandini S, Garibaldi C, Gerszten PC, Gillessen S, Grubb WR, Guckenberger M, Hannan R, Jhaveri PM, Josipovic M, Kerkmeijer LGW, Lehrer EJ, Lindskog M, Louie AV, Nguyen QN, Ost P, Palma DA, Procopio G, Rossi M, Staehler M, Tree AC, Tsang YM, Van As N, Zaorsky NG, Zilli T, Pasquier D, Siva S. Delphi consensus on stereotactic ablative radiotherapy for oligometastatic and oligoprogressive renal cell carcinoma-a European Society for Radiotherapy and Oncology study endorsed by the European Association of Urology. Lancet Oncol. 2024 May; 25 (5):e193-e204 View PubMed Sheehan JP, Trifiletti DM, Lehrer EJ. Tissue Biopsy before Resection in Glioblastoma: Is there an Opportunity to Improve Outcomes with Liquid Biopsies and Pre-operative Stereotactic Radiosurgery Journal of Neuro-Oncology. 2024. Palmer JD, Perlow HK, Lehrer EJ, Wardak Z, Soliman H. Novel radiotherapeutic strategies in the management of brain metastases: Challenging the dogma. Neuro Oncol. 2024 Mar 4; 26 (12 Suppl 2):S46-S55 View PubMed El-Hajj VG, Ghaith AK, Nguyen RH, Al-Saidi NN, Hoang H, Graepel SP, Elmi-Terander A, Lehrer EJ, Brown P, Bydon M. Analysis of demographics and the impact of adjuvant radiotherapy on a nationwide cohort of patients with high-grade spinal meningiomas. Neurooncol Adv. 2024 Jan-Dec; 6 (1):vdae018 Epub 2024 Feb 05 View PubMed Stephens CR, Bloom JR, Lehrer EJ, Sheu RD, Tabrizian P, Rocha C, Kim-Schluger L, Florman SS, Buckstein MH. Outcomes for salvage abdominal stereotactic body radiation therapy for hepatocellular carcinoma after liver transplantation. Liver Transpl. 2023 Nov 1; 29 (11):1245-1248 Epub 2023 June 05 View PubMed Lehrer EJ, Gurewitz J, Kondziolka D, Niranjan A, Lunsford LD, Mathieu D, Deibert C, Ruiz-Garcia H, Patel SI, Bonney P, Hwang L, Zada G, Picozzi P, Prasad RN, Palmer JD, Lee CC, Rusthoven CG Jr, Sheehan JP, Trifiletti DM, Ahluwalia M. Immune Checkpoint Inhibition and Single Fraction Stereotactic Radiosurgery in Non-Small Cell Lung Cancer Brain Metastases: An International Multicenter Study of 395 Patients. Int J Radiat Oncol Biol Phys. 2023 Oct 1; 117 (2S):e127-e128 View PubMed Crompton D, Koffler D, Fekrmandi F, Lehrer EJ, Sheehan JP, Trifiletti DM. Preoperative stereotactic radiosurgery as neoadjuvant therapy for resectable brain tumors. J Neurooncol. 2023 Oct; 165 (1):21-28 Epub 2023 Oct 27 View PubMed Lehrer EJ, Khosla AA, Ozair A, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Mathieu D, Trudel C, Deibert CP, Malouff TD, Ruiz-Garcia H, Peterson JL, Patel S, Bonney P, Hwang L, Yu C, Zada G, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Fakhoury KR, Rusthoven CG, Dickstein DR, Sheehan JP, Trifiletti DM, Ahluwalia MS. Immune checkpoint inhibition and single fraction stereotactic radiosurgery in brain metastases from non-small cell lung cancer: an international multicenter study of 395 patients. J Neurooncol. 2023 Oct; 165 (1):63-77 Epub 2023 Oct 27 View PubMed Bloom JR, Hotca A, Cherry DR, Dickstein DR, Runnels J, Samstein RM, Veluswamy RR, Rosenzweig KE, Brown PD, Trifiletti DM, Palmer JD, Singh R, Breen WG, Lehrer EJ. The incorporation of cognitive-sparing techniques into prophylactic cranial irradiation in the management of small cell lung cancer. Chin Clin Oncol. 2023 Aug; 12 (4):44 Epub 2023 July 29 View PubMed Lehrer EJ, Kowalchuk RO, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Fakhoury KR, Rusthoven CG, Mathieu D, Trudel C, Malouff TD, Ruiz-Garcia H, Bonney P, Hwang L, Yu C, Zada G, Patel S, Deibert CP, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Harmsen WS, Jones BM, Sharma S, Ahluwalia MS, Sheehan JP, Trifiletti DM. Concurrent Administration of Immune Checkpoint Inhibitors and Single Fraction Stereotactic Radiosurgery in Patients With Non-Small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma Brain Metastases. Int J Radiat Oncol Biol Phys. 2023 Jul 15; 116 (4):858-868 Epub 2023 Jan 21 View PubMed Hsieh K, Dickstein DR, Runnels J, Lehrer EJ, Rosenzweig K, Hirsch FR, Samstein RM. Radiotherapy and Immunotherapy in Lung Cancer. Biomedicines. 2023 Jun 6; 11 (6) Epub 2023 June 06 View PubMed Dickstein DR, Edwards CR, Lehrer EJ, Tarras ES, Gallitto M, Sfakianos J, Galsky MD, Stock R, Safer JD, Rosser BRS, Marshall DC. Sexual health and treatment-related sexual dysfunction in sexual and gender minorities with prostate cancer. Nat Rev Urol. 2023 Jun; 20 (6):332-355 Epub 2023 May 22 View PubMed Hudock NL, Mani K, Khunsriraksakul C, Walter V, Nekhlyudov L, Wang M, Lehrer EJ, Hudock MR, Liu DJ, Spratt DE, Zaorsky NG. Future trends in incidence and long-term survival of metastatic cancer in the United States. Commun Med (Lond). 2023 May 27; 3 (1):76 View PubMed Lehrer EJ, Ahluwalia MS, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Fakhoury KR, Rusthoven CG, Mathieu D, Trudel C, Malouff TD, Ruiz-Garcia H, Bonney P, Hwang L, Yu C, Zada G, Patel S, Deibert CP, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Jones BM, Green S, Sheehan JP, Trifiletti DM. Imaging-defined necrosis after treatment with single-fraction stereotactic radiosurgery and immune checkpoint inhibitors and its potential association with improved outcomes in patients with brain metastases: an international multicenter study of 697 patients. J Neurosurg. 2023 May 1; 138 (5):1178-1187 Epub 2022 Sept 16 View PubMed Lehrer EJ, Ahluwalia MS, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei ZS, Lunsford LD, Fakhoury KR, Rusthoven CG, Mathieu D, Trudel C, Malouff TD, Ruiz-Garcia H, Bonney P, Hwang L, Yu C, Zada G, Patel S, Deibert CP, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Jones BM, Green S, Sheehan JP, Trifiletti DM. Imaging-defined necrosis after treatment with single-fraction stereotactic radiosurgery and immune checkpoint inhibitors and its potential association with improved outcomes in patients with brain metastases: an international multicenter study of 697 patients. Journal of Neurosurgery. 2023 May; 138 (5):1178-87 Jones BM, Villavisanis DF, Lehrer EJ, Dickstein DR, Sindhu KK, Misiukiewicz KJ, Posner M, Liu JT, Gupta V, Sharma S, Roof SA, Teng M, Genden EM, Bakst RL. High Failure Rates in Young Nonsmoker Nondrinkers With Squamous Cell Carcinoma of the Oral Tongue. Laryngoscope. 2023 May; 133 (5):1110-1121 Epub 2022 June 18 View PubMed Lehrer EJ, Kowalchuk RO, Trifiletti DM, Sheehan JP. The Role of Stereotactic Radiosurgery for Functioning and Nonfunctioning Pituitary Adenomas. Neurol India. 2023 Mar-Apr; 71 (Supplement):S133-S139 View PubMed Jones BM, Rowley JP, Sindhu KK, Lehrer EJ, Hsieh K, Nehlsen AD, Green S, Goodman KA. Gender Differences in the Research Productivity of Radiation Oncology Resident Graduates in the United States: 2015 to 2019. Adv Radiat Oncol. 2023 Mar-Apr; 8 (2):101135 Epub 2022 Nov 28 View PubMed Sindhu KK, Rowley JP, Smith WH, Nehlsen AD, Smith AW, Lehrer EJ, Jones BM, Buckstein M, Lazarev S, Rosenzweig KE. The Rise of Open Access Journals in Radiation Oncology: Influence on Resident Research, 2015 to 2019. Adv Radiat Oncol. 2023 Mar-Apr; 8 (2):101121 Epub 2022 Nov 07 View PubMed Singh R, Valluri A, Didwania P, Lehrer EJ, Baliga S, Hiniker S, Braunstein SE, Murphy ES, Lazarev S, Tinkle C, Terezakis S, Palmer JD. Efficacy and Safety of Stereotactic Body Radiation Therapy for Pediatric Malignancies: The LITE-SABR Systematic Review and Meta-Analysis. Adv Radiat Oncol. 2023 Mar-Apr; 8 (2):101123 Epub 2023 Jan 05 View PubMed Lehrer EJ, Gurewitz J, Bernstein K, Kondziolka D, Fakhoury KR, Rusthoven CG, Niranjan A, Wei Z, Lunsford LD, Malouff TD, Ruiz-Garcia H, Peterson JL, Bonney P, Hwang L, Yu C, Zada G, Deibert CP, Prasad RN, Raval RR, Palmer JD, Patel S, Picozzi P, Franzini A, Attuati L, Mathieu D, Trudel C, Lee CC, Yang HC, Jones BM, Green S, Ahluwalia MS, Sheehan JP, Trifiletti DM. Concurrent Administration of Immune Checkpoint Inhibitors and Stereotactic Radiosurgery Is Well-Tolerated in Patients With Melanoma Brain Metastases: An International Multicenter Study of 203 Patients. Neurosurgery. 2022 Dec 1; 91 (6):872-882 Epub 2022 Oct 18 View PubMed Ryckman JM, Thomas TV, Wang M, Wu X, Siva S, Spratt DE, Slotman B, Pal S, Chapin BF, Fitzal F, Soran A, Bex A, Louie AV, Lehrer EJ, Zaorsky NG. Local Treatment of the Primary Tumor for Patients With Metastatic Cancer (PRIME-TX): A Meta-Analysis. Int J Radiat Oncol Biol Phys. 2022 Dec 1; 114 (5):919-935 Epub 2022 July 15 View PubMed Lehrer EJ, Jones BM, Sindhu KK, Dickstein DR, Cohen M, Lazarev S, Quinones-Hinojosa A, Green S, Trifiletti DM. A Review of the Role of Stereotactic Radiosurgery and Immunotherapy in the Management of Primary Central Nervous System Tumors. Biomedicines. 2022 Nov 19; 10 (11) View PubMed Sindhu KK, Nehlsen AD, Lehrer EJ, Rowley JP, Stock RG, Galsky MD, Buckstein M. Oligoprogression of Solid Tumors on Immune Checkpoint Inhibitors: The Impact of Local Ablative Radiation Therapy. Biomedicines. 2022 Oct 5; 10 (10) Epub 2022 Oct 05 View PubMed Matsui JK, Perlow HK, Raj RK, Nalin AP, Lehrer EJ, Kotecha R, Trifiletti DM, McClelland S 3rd, Kendra K, Williams N, Owen DH, Presley CJ, Thomas EM, Beyer SJ, Blakaj DM, Ahluwalia MS, Raval RR, Palmer JD. Treatment of Brain Metastases: The Synergy of Radiotherapy and Immune Checkpoint Inhibitors. Biomedicines. 2022 Sep 7; 10 (9) Epub 2022 Sept 07 View PubMed Vaishnav YJ, Singh R, Didwania P, Lehrer EJ, Bakaeva T, Harris TJ, Migliori ME, Sheehan JP, Trifiletti DM. Radiotherapy and Radiosurgery in the Management of Optic Nerve Sheath Meningiomas: An International Systematic Review and Meta-Analysis of Twenty Studies. World Neurosurg. 2022 Aug; 164:e929-e944. Epub 2022 May 21. View PubMed Labe SA, Wang X, Lehrer EJ, Kishan AU, Spratt DE, Lin C, Morgans AK, Ponsky L, Garcia JA, Garrett S, Wang M, Zaorsky NG. Identification and Validation of the Prognostic Impact of Metastatic Prostate Cancer Phenotypes. Clin Genitourin Cancer. 2022 Aug; 20 (4):371-380 Epub 2022 Feb 24 View PubMed Sindhu KK, Jones BM, Nehlsen AD, Lehrer EJ, Smith AW, Rowley JP. In Regard to Huang et al. Adv Radiat Oncol. 2022 Jul-Aug; 7 (4):100932 Epub 2022 July 15 View PubMed Dickstein DR, Lehrer EJ, Hsieh K, Hotca A, Jones BM, Powers A, Sharma S, Liu J, Gupta V, Mell L, Husain Z, Kirke D, Misiukiewicz K, Posner M, Genden E, Bakst RL. Management of Older Adults with Locally Advanced Head and Neck Cancer. Cancers (Basel). 2022 Jun 5; 14 (11) Epub 2022 June 05 View PubMed Kim Y, Lehrer EJ, Wirth PJ, Khesroh EA, Brewer JD, Billingsley EM, Zaorsky NG, Lam C. Adjuvant radiotherapy may not significantly change outcomes in high-risk cutaneous squamous cell carcinomas with clear surgical margins: A systematic review and meta-analysis. J Am Acad Dermatol. 2022 Jun; 86(6):1246-1257. Epub 2021 Dec 07. View PubMed Ryan C, Stoltzfus KC, Horn S, Chen H, Louie AV, Lehrer EJ, Trifiletti DM, Fox EJ, Abraham JA, Zaorsky NG. Epidemiology of bone metastases. Bone. 2022 May; 158:115783. Epub 2020 Dec 01. View PubMed Hatten SJ Jr, Lehrer EJ, Liao J, Sha CM, Trifiletti DM, Siva S, McBride SM, Palma D, Holder SL, Zaorsky NG. A Patient-Level Data Meta-analysis of the Abscopal Effect. Adv Radiat Oncol. 2022 May-Jun; 7 (3):100909 Epub 2022 Mar 03 View PubMed Lehrer EJ, Gurewitz J, Bernstein K, Patel D, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Malouff TD, Ruiz-Garcia H, Patel S, Bonney PA, Hwang L, Yu C, Zada G, Mathieu D, Trudel C, Prasad RN, Palmer JD, Jones BM, Sharma S, Fakhoury KR, Rusthoven CG, Deibert CP, Picozzi P, Franzini A, Attuati L, Lee CC, Yang HC, Ahluwalia MS, Sheehan JP, Trifiletti DM. Radiation necrosis in renal cell carcinoma brain metastases treated with checkpoint inhibitors and radiosurgery: An international multicenter study. Cancer. 2022 Apr 01; 128(7):1429-1438. Epub 2022 Jan 25. View PubMed Nehlsen AD, Sindhu KK, Jones BM, Lehrer EJ, Rowley JP, Bakst RL. Moving beyond Definitive Therapy: Increasing Physical Activity in Survivors of Cancers of the Head and Neck. Curr Oncol. 2022 Feb 17; 29 (2):1213-1222 View PubMed Jones BM, Lehrer EJ, Saraf A, Shafaee Z, Resende Salgado L, Osborn VW. Healthcare Disparities and Outcomes of Cancer Patients in a Community Setting from a COVID-19 Epicenter. Curr Oncol. 2022 Feb 16; 29 (2):1150-1162 View PubMed Zaorsky NG, Wang X, Lehrer EJ, Tchelebi LT, Prasad V, Chinchilli V, & Wang M. Retrospective observational studies cannot be used for comparative effectiveness research because they yield results desired by investigators. Int J Cancer Int J Cancer. 2022. Lehrer EJ, Ruiz-Garcia H, Nehlsen AD, Sindhu KK, Estrada RS, Borst GR, Sheehan JP, Quinones-Hinojosa A, Trifiletti DM. Preoperative Stereotactic Radiosurgery for Glioblastoma. Biology (Basel). 2022 Jan 26; 11 (2) View PubMed Zaorsky NG, Wang X, Garrett SM, Lehrer EJ, Lin C, DeGraff DJ, Spratt DE, Trifiletti DM, Kishan AU, Showalter TN, Park HS, Yang JT, Chinchilli VM, Wang M. Pan-cancer analysis of prognostic metastatic phenotypes. Int J Cancer. 2022 Jan 1; 150 (1):132-141 Epub 2021 Aug 27 View PubMed Waqar M, Roncaroli F, Lehrer EJ, Palmer JD, Villanueva-Meyer J, Braunstein S, Hall E, Aznar M, De Witt Hamer PC, D'Urso PI, Trifiletti D, Quinones-Hinojosa A, Wesseling P, Borst GR. Rapid early progression (REP) of glioblastoma is an independent negative prognostic factor: Results from a systematic review and meta-analysis. Neurooncol Adv. 2022 Jan-Dec; 4 (1):vdac075 Epub 2022 June 04 View PubMed Lehrer EJ, Jones BM, Dickstein DR, Green S, Germano IM, Palmer JD, Laack N, Brown PD, Gondi V, Wefel JS, Sheehan JP, Trifiletti DM. The Cognitive Effects of Radiotherapy for Brain Metastases. Front Oncol. 2022; 12:893264. Epub 2022 Jun 30. View PubMed Agha A, Wang X, Wang M, Lehrer EJ, Horn SR, Rosenberg JC, Trifiletti DM, Diaz R, Louie AV, Zaorsky NG. Long-Term Risk of Death From Heart Disease Among Breast Cancer Patients. Front Cardiovasc Med. 2022; 9:784409. Epub 2022 Apr 13. View PubMed Singh R, Didwania P, Lehrer EJ, Palmer JD, Trifiletti DM, Sheehan JP. Repeat stereotactic radiosurgery for locally recurrent brain metastases previously treated with stereotactic radiosurgery: A systematic review and meta-analysis of efficacy and safety. J Radiosurg SBRT. 2022; 8 (1):1-10 View PubMed Lehrer EJ, Kowalchuk RO, Ruiz-Garcia H, Merrell KW, Brown PD, Palmer JD, Burri SH, Sheehan JP, Quninoes-Hinojosa A, Trifiletti DM. Preoperative stereotactic radiosurgery in the management of brain metastases and gliomas. Front Surg. 2022; 9:972727 Epub 2022 Oct 24 View PubMed Hardy-Abeloos C, Lehrer EJ, Nehlsen AD, Sindhu KK, Rowley JP, Sheu R, Rosenzweig KE, Buckstein M. Characterization of rib fracture development following liver directed stereotactic body radiation therapy. J Radiosurg SBRT. 2022; 8 (2):109-116 View PubMed Lehrer EJ, Stoltzfus KC, Jones BM, Gusani NJ, Walter V, Wang M, Trifiletti DM, Siva S, Louie AV, Zaorsky NG. Trends in Diagnosis and Treatment of Metastatic Cancer in the United States. Am J Clin Oncol. 2021 Nov 1; 44 (11):572-579 View PubMed Sindhu KK, Rowley JP, Smith WH, Nehlsen AD, Smith AW, Lehrer EJ, Lazarev S, Rosenzweig KE, Buckstein M. The Holman Research Pathway in Radiation Oncology: 2010 to 2019. Int J Radiat Oncol Biol Phys. 2021 Nov 1; 111 (3):627-637 Epub 2021 June 18 View PubMed Nehlsen AD, Lehrer EJ, Resende-Salgado L, Rosenzweig KE, Buckstein M. Comparison of Pathologic Complete Response Rates and Oncologic Outcomes in Patients With Surgically Resectable Esophageal Cancer Treated With Neoadjuvant Chemoradiation to 50.4 Gy vs 41.4 Gy. Cureus. 2021 Nov; 13 (11):e19233 Epub 2021 Nov 03 View PubMed Singh R, Lehrer EJ, Wang M, Perlow HK, Zaorsky NG, Trifiletti DM, Bovi J, Navarria P, Scoccianti S, Gondi V, Brown PD, Palmer JD. Dose Escalated Radiation Therapy for Glioblastoma Multiforme: An International Systematic Review and Meta-Analysis of 22 Prospective Trials. Int J Radiat Oncol Biol Phys. 2021 Oct 01; 111(2):371-384. Epub 2021 May 12. View PubMed Valle LF, Lehrer EJ, Markovic D, Elashoff D, Levin-Epstein R, Karnes RJ, Reiter RE, Rettig M, Calais J, Nickols NG, Dess RT, Spratt DE, Steinberg ML, Nguyen PL, Davis BJ, Zaorsky NG, Kishan AU. A Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER). Eur Urol. 2021 Sep; 80 (3):280-292 Epub 2020 Dec 11 View PubMed Tchelebi LT, Batchelder E, Wang M, Lehrer EJ, Drabick JJ, Sharma N, Machtay M, Trifiletti DM, Zaorsky NG. Radiotherapy and Receptor Tyrosine Kinase Inhibition for Solid Cancers (ROCKIT): A Meta-Analysis of 13 Studies. JNCI Cancer Spectr. 2021 Aug; 5(4). Epub 2021 May 19. View PubMed El Sayed I, Trifiletti DM, Lehrer EJ, Showalter TN, Dutta SW. Protons versus photons for the treatment of chordoma. Cochrane Database Syst Rev. 2021 Jul 01; 7(7):CD013224. View PubMed Sindhu KK, Lehrer EJ, Dharmarajan KV. Identifying areas of emphasis for future palliative radiation therapy curricula via an examination of theMednet. Ann Palliat Med. 2021 Jul; 10 (7):7370-7377 Epub 2021 July 05 View PubMed Michael CM, Lehrer EJ, Schmitz KH, Zaorsky NG. Prehabilitation exercise therapy for cancer: A systematic review and meta-analysis. Cancer Med. 2021 Jul; 10 (13):4195-4205 Epub 2021 June 10 View PubMed Nehlsen AD, Lehrer EJ, Dickstein DR, Posner MR, Misiukiewicz K, Liu J, Gupta V, Bakst RL, Sharma S. Functional Larynx Preservation in Patients With Locally Advanced Squamous Cell Carcinoma of the Larynx and Hypopharynx Treated With Induction Chemotherapy vs. Concurrent Chemoradiation Alone. Cureus. 2021 Jul; 13 (7):e16310 Epub 2021 July 11 View PubMed Ha GL, Lehrer EJ, Wang M, Holliday E, Jagsi R, Zaorsky NG. Sex Differences in Academic Productivity Across Academic Ranks and Specialties in Academic Medicine: A Systematic Review and Meta-analysis. JAMA Netw Open. 2021 Jun 1; 4 (6):e2112404 Epub 2021 June 01 View PubMed Smith AW, Gallitto M, Lehrer EJ, Wasserman I, Gupta V, Sharma S, Liu JT, Posner M, Misiukiewicz K, Westra WH, Genden EM, Haidar Y, Yao M, Teng MS, Miles BA, Bakst RL. Redefining risk of contralateral cervical nodal disease in early stage oropharyngeal cancer in the human papillomavirus era. Head Neck. 2021 May; 43 (5):1409-1414 Epub 2021 Jan 21 View PubMed Cooke P, Sindhu KK, Lehrer EJ, Maron SZ, Rosenzweig KE, Buckstein M. Palliating Symptoms in Patients With Hepatocellular Carcinoma Involving the Inferior Vena Cava With External Beam Radiation Therapy. Cureus. 2021 Mar 25; 13 (3):e14107 View PubMed Rowley JP, Sindhu KK, Smith WH, Nehlsen AD, Smith AW, Lehrer EJ, Buckstein M, Lazarev S. Radiation Oncology Resident Research Productivity in the United States: 2015 to 2019. Int J Radiat Oncol Biol Phys. 2021 Mar 15; 109 (4):1111-1118 Epub 2020 Oct 24 View PubMed Kothari G, Korte J, Lehrer EJ, Zaorsky NG, Lazarakis S, Kron T, Hardcastle N, Siva S. A systematic review and meta-analysis of the prognostic value of radiomics based models in non-small cell lung cancer treated with curative radiotherapy. Radiother Oncol. 2021 Feb; 155:188-203 Epub 2020 Oct 21 View PubMed Lehrer EJ, Prabhu AV, Sindhu KK, Lazarev S, Ruiz-Garcia H, Peterson JL, Beltran C, Furutani K, Schlesinger D, Sheehan JP, Trifiletti DM. Proton and Heavy Particle Intracranial Radiosurgery. Biomedicines. 2021 Jan 3; 9 (1) Epub 2021 Jan 03 View PubMed Lehrer EJ, McGee HM, Sheehan JP, Trifiletti DM. Integration of immuno-oncology with stereotactic radiosurgery in the management of brain metastases. J Neurooncol. 2021 Jan; 151(1):75-84. Epub 2020 Feb 12. View PubMed Lehrer EJ, Singh R, Wang M, Chinchilli VM, Trifiletti DM, Ost P, Siva S, Meng MB, Tchelebi L, Zaorsky NG. Safety and Survival Rates Associated With Ablative Stereotactic Radiotherapy for Patients With Oligometastatic Cancer: A Systematic Review and Meta-analysis. JAMA Oncol. 2021 Jan 01; 7(1):92-106. View PubMed Chen H, Stoltzfus KC, Lehrer EJ, Horn SR, Siva S, Trifiletti DM, Meng MB, Verma V, Louie AV, Zaorsky NG. The Epidemiology of Lung Metastases. Front Med (Lausanne). 2021; 8:723396. Epub 2021 Sep 20. View PubMed Lara-Velazquez M, Shireman JM, Lehrer EJ, Bowman KM, Ruiz-Garcia H, Paukner MJ, Chappell RJ, Dey M. A Comparison Between Chemo-Radiotherapy Combined With Immunotherapy and Chemo-Radiotherapy Alone for the Treatment of Newly Diagnosed Glioblastoma: A Systematic Review and Meta-Analysis. Front Oncol. 2021; 11:662302 Epub 2021 May 11 View PubMed Hasan S, Gorovets D, Lehrer E, Lazarev S, Press RH, Garg M, Mehta KJ, Chhabra AM, Isabelle Choi J, Simone CB 2nd. Optimal timing of radiotherapy in high risk prostate cancer: Do missed days matter? Clin Transl Radiat Oncol. 2021 Jan; 26:47-54 Epub 2020 Nov 25 View PubMed Scott AR, Stoltzfus KC, Tchelebi LT, Trifiletti DM, Lehrer EJ, Rao P, Bleyer A, Zaorsky NG. Trends in Cancer Incidence in US Adolescents and Young Adults, 1973-2015. JAMA Netw Open. 2020 Dec 1; 3 (12):e2027738 Epub 2020 Dec 01 View PubMed Schlussel Markovic E, Marqueen KE, Sindhu KK, Lehrer EJ, Liu J, Miles B, Genden E, Sharma S, Gupta V, Westra W, Iloreta A, Posner M, Misiukiewicz K, Bakst RL. The prognostic significance of human papilloma virus in sinonasal squamous cell carcinoma. Laryngoscope Investig Otolaryngol. 2020 Dec; 5 (6):1070-1078 Epub 2020 Nov 04 View PubMed Wright C, Verma V, Barsky AR, Haque W, Polamraju PV, Ludmir EB, Zaorsky NG, Lehrer EJ, Trifiletti DM, Grover S, Friedberg JS, Simone CB 2nd. Quantitation and predictors of short-term mortality following extrapleural pneumonectomy, pleurectomy/decortication, and nonoperative management for malignant pleural mesothelioma. J Thorac Dis. 2020 Nov; 12(11):6476-6493. View PubMed Sanmamed N, Glicksman RM, Herrera-Caceres J, Lehrer EJ, Heaton J, Hansen AR, Chung P, Fleshner NE, Den RB, Zaorsky NG, Berlin A. Use of combined androgen deprivation therapy with postoperative radiation treatment for prostate cancer: Impact of randomized trials on clinical practice. Urol Oncol. 2020 Nov; 38 (11):848.e1-848.e7 Epub 2020 June 16 View PubMed Sha CM, Lehrer EJ, Hwang C, Trifiletti DM, Mackley HB, Drabick JJ, Zaorsky NG. Toxicity in combination immune checkpoint inhibitor and radiation therapy: A systematic review and meta-analysis. Radiother Oncol. 2020 Oct; 151:141-148. Epub 2020 Jul 24. View PubMed Levin-Epstein R, Cook RR, Wong JK, Stock RG, Jeffrey Demanes D, Collins SP, Aghdam N, Suy S, Mantz C, Katz AJ, Nickols NG, Miszczyk L, Napieralska A, Namysl-Kaletka A, Prionas ND, Bagshaw H, Buyyounouski MK, Cao M, Mahal BA, Shabsovich D, Dang A, Yuan Y, Rettig MB, Chang AJ, Jackson WC, Spratt DE, Lehrer EJ, Zaorsky NG, Kupelian PA, Steinberg ML, Horwitz EM, Jiang NY, Kishan AU. Prostate-specific antigen kinetics and biochemical control following stereotactic body radiation therapy, high dose rate brachytherapy, and low dose rate brachytherapy: A multi-institutional analysis of 3502 patients. Radiother Oncol. 2020 Oct; 151:26-32 Epub 2020 July 11 View PubMed Horn SR, Stoltzfus KC, Lehrer EJ, Dawson LA, Tchelebi L, Gusani NJ, Sharma NK, Chen H, Trifiletti DM, Zaorsky NG. Epidemiology of liver metastases. Cancer Epidemiol. 2020 Aug; 67:101760 Epub 2020 June 17 View PubMed Prabhu AV, Lehrer EJ, Clump DA 2nd, Kim T. Federal Political Contribution Characteristics of Radiation Oncologists in the United States from 2003 to 2018. Int J Radiat Oncol Biol Phys. 2020 Jul 15; 107 (4):836-843 Epub 2020 Apr 15 View PubMed Horn SR, Stoltzfus KC, Mackley HB, Lehrer EJ, Zhou S, Dandekar SC, Fox EJ, Rizk EB, Trifiletti DM, Rao PM, Zaorsky NG. Long-term causes of death among pediatric patients with cancer. Cancer. 2020 Jul 1; 126 (13):3102-3113 Epub 2020 Apr 16 View PubMed Suarez-Meade P, Marenco-Hillembrand L, Prevatt C, Murguia-Fuentes R, Mohamed A, Alsaeed T, Lehrer EJ, Brigham T, Ruiz-Garcia H, Sabsevitz D, Middlebrooks EH, Bechtle PS, Quinones-Hinojosa A, Chaichana KL. Awake vs. asleep motor mapping for glioma resection: a systematic review and meta-analysis. Acta Neurochir (Wien). 2020 Jul; 162 (7):1709-1720 Epub 2020 May 09 View PubMed Lehrer EJ, Kishan AU, Yu JB, Trifiletti DM, Showalter TN, Ellis R, Zaorsky NG. Ultrahypofractionated versus hypofractionated and conventionally fractionated radiation therapy for localized prostate cancer: A systematic review and meta-analysis of phase III randomized trials. Radiother Oncol. 2020 Jul; 148:235-242 Epub 2020 Apr 28 View PubMed Singh R, Didwania P, Lehrer EJ, Sheehan D, Sheehan K, Trifiletti DM, Sheehan JP. Stereotactic radiosurgery for acromegaly: an international systematic review and meta-analysis of clinical outcomes. J Neurooncol. 2020 Jul; 148 (3):401-418 Epub 2020 June 06 View PubMed Lehrer EJ, Snyder MH, Desai BD, Li CE, Narayan A, Trifiletti DM, Schlesinger D, Sheehan JP. Clinical and radiographic adverse events after Gamma Knife radiosurgery for brainstem lesions: A dosimetric analysis. Radiother Oncol. 2020 Jun; 147:200-209. Epub 2020 May 13. View PubMed Tchelebi LT, Lehrer EJ, Trifiletti DM, Sharma NK, Gusani NJ, Crane CH, Zaorsky NG. Conventionally fractionated radiation therapy versus stereotactic body radiation therapy for locally advanced pancreatic cancer (CRiSP): An international systematic review and meta-analysis. Cancer. 2020 May 15; 126 (10):2120-2131 Epub 2020 Mar 03 View PubMed Singh R, Lehrer EJ, Dahshan B, Palmer JD, Sahgal A, Gerszten PC, Zaorsky NG, Trifiletti DM. Single fraction radiosurgery, fractionated radiosurgery, and conventional radiotherapy for spinal oligometastasis (SAFFRON): A systematic review and meta-analysis. Radiother Oncol. 2020 May; 146:76-89 Epub 2020 Feb 28 View PubMed Patel RR, Ludmir EB, Augustyn A, Zaorsky NG, Lehrer EJ, Ryali R, Trifiletti DM, Adeberg S, Amini A, Verma V. De-intensification of therapy in human papillomavirus associated oropharyngeal cancer: A systematic review of prospective trials. Oral Oncol. 2020 Apr; 103:104608 Epub 2020 Mar 09 View PubMed Singh R, Lehrer EJ, Ko S, Peterson J, Lou Y, Porter AB, Kotecha R, Brown PD, Zaorsky NG, Trifiletti DM. Brain metastases from non-small cell lung cancer with EGFR or ALK mutations: A systematic review and meta-analysis of multidisciplinary approaches. Radiother Oncol. 2020 Mar; 144:165-179 Epub 2019 Dec 05 View PubMed Singh R, Stoltzfus KC, Chen H, Louie AV, Lehrer EJ, Horn SR, Palmer JD, Trifiletti DM, Brown PD, Zaorsky NG. Epidemiology of synchronous brain metastases. Neurooncol Adv. 2020 Jan-Dec; 2 (1):vdaa041 Epub 2020 Apr 24 View PubMed Correa RJM, Louie AV, Zaorsky NG, Lehrer EJ, Ellis R, Ponsky L, Kaplan I, Mahadevan A, Chu W, Swaminath A, Hannan R, Onishi H, Teh BS, Muacevic A, Lo SS, Staehler M, Siva S. The Emerging Role of Stereotactic Ablative Radiotherapy for Primary Renal Cell Carcinoma: A Systematic Review and Meta-Analysis. Eur Urol Focus. 2019 Nov; 5 (6):958-969 Epub 2019 June 24 View PubMed Lee CT, Lehrer EJ, Aphale A, Lango M, Galloway TJ, Zaorsky NG. Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients. Cancer. 2019 Oct 15; 125 (20):3582-3594 Epub 2019 July 29 View PubMed Haynes BA, Yang LF, Huyck RW, Lehrer EJ, Turner JM, Barabutis N, Correll VL, Mathiesen A, McPheat W, Semmes OJ, Dobrian AD. Endothelial-to-Mesenchymal Transition in Human Adipose Tissue Vasculature Alters the Particulate Secretome and Induces Endothelial Dysfunction. Arterioscler Thromb Vasc Biol. 2019 Oct; 39 (10):2168-2191 Epub 2019 Aug 22 View PubMed Zaorsky NG, Lehrer EJ, Kothari G, Louie AV, Siva S. Stereotactic ablative radiation therapy for oligometastatic renal cell carcinoma (SABR ORCA): a meta-analysis of 28 studies. Eur Urol Oncol. 2019 Sep; 2 (5):515-523 Epub 2019 July 11 View PubMed Cummings M, Lehrer EJ, Drabick JJ, Gusani NJ, Trifiletti DM, Zaorsky NG. Exceptional Responders in Oncology: A Systematic Review and Meta-Analysis of Patient Level Data. Am J Clin Oncol. 2019 Aug; 42(8):624-635. View PubMed Lin D, Lehrer EJ, Rosenberg J, Trifiletti DM, Zaorsky NG. Toxicity after radiotherapy in patients with historically accepted contraindications to treatment (CONTRAD): An international systematic review and meta-analysis. Radiother Oncol. 2019 Jun; 135:147-152. Epub 2019 Mar 27. View PubMed Lehrer EJ, Peterson JL, Zaorsky NG, Brown PD, Sahgal A, Chiang VL, Chao ST, Sheehan JP, Trifiletti DM. Single versus Multifraction Stereotactic Radiosurgery for Large Brain Metastases: An International Meta-analysis of 24 Trials. Int J Radiat Oncol Biol Phys. 2019 Mar 01; 103(3):618-630. Epub 2018 Nov 02. View PubMed Lehrer EJ, Peterson J, Brown PD, Sheehan JP, Quiñones-Hinojosa A, Zaorsky NG, Trifiletti DM. Treatment of brain metastases with stereotactic radiosurgery and immune checkpoint inhibitors: An international meta-analysis of individual patient data. Radiother Oncol. 2019 Jan; 130:104-112. Epub 2018 Sep 18. View PubMed Leon J, Lehrer EJ, Peterson J, Vallow L, Ruiz-Garcia H, Hadley A, Herchko S, Lundy L, Chaichana K, Vibhute P, Sheehan JP, Trifiletti DM. Observation or stereotactic radiosurgery for newly diagnosed vestibular schwannomas: A systematic review and meta-analysis. J Radiosurg SBRT. 2019; 6(2):91-100. View PubMed Zaorsky NG, Lehrer EJ, Handorf E, Meyer JE. Dose Escalation in Stereotactic Body Radiation Therapy for Pancreatic Cancer: A Meta-Analysis. Am J Clin Oncol. 2019 Jan; 42 (1):46-55 View PubMed Dutta SW, Sayed IE, Lehrer EJ, Showalter TN, Jha RK, Khan L, Trifiletti DM. Particles versus photons for the treatment of chordoma. Cochrane Database of Systematic Reviews. 2018 Dec 17; 2018 (12):CD013224 Lehrer EJ, McGee HM, Peterson JL, Vallow L, Ruiz-Garcia H, Zaorsky NG, Sharma S, Trifiletti DM. Stereotactic Radiosurgery and Immune Checkpoint Inhibitors in the Management of Brain Metastases. Int J Mol Sci. 2018 Oct 07; 19(10). View PubMed Dobrian AD, Ma K, Glenn LM, Hatcher MA, Haynes BA, Lehrer EJ, Kaplan MH, Nadler JL. Key Role of STAT4 Deficiency in the Hematopoietic Compartment in Insulin Resistance and Adipose Tissue Inflammation. Mediators Inflamm. 2017; 2017:5420718 Epub 2017 Mar 16 View PubMed PST-20553558 Home Publications