Publications Print Tucker J, Sharma V, Johnson M, Hibbert R, Kapplinger J, Moynagh M, Adamo D, Schmitz J, Parvinian A. Safety and Diagnostic Yield of Percutaneous Urinary Bladder Tumor Biopsy. Abdom Radiol (NY). 2026 Mar; 51 (3):1444-1449 Epub 2025 July 28 View PubMed Bilgin C, Belge Bilgin G, Dundar B, Kapplinger JD, Hallanger Johnson JE, Bogsrud TV, Durski JM. I-131 Uptake in a Benign Diaphragmatic Mesothelial Cyst Mimicking Thyroid Cancer Metastasis on Post-therapy SPECT/CT. Clin Nucl Med. 2025 Oct 1; 50 (10):958-959 Epub 2025 July 01 View PubMed Malyuk DF, Hibbert RM, Parvinian A, Kirby JW, Jaykel TJ, Kapplinger JD. Safety and diagnostic yield of percutaneous ultrasound-guided penile mass biopsy. Abdom Radiol (NY). 2025 Jul 14 Epub 2025 July 14 View PubMed Gits HC, Khosravi Flanigan MA, Kapplinger JD, Reisenauer JS, Eiken PW, Breen WG, Vu LH, Welch BT, Harmsen WS, Day CN, Olivier KR, Park SS, Garces YI, Hallemeier CL, Merrell KW, Ashman JB, Schild SE, Grams MP, Lucido JJ, Shen KR, Cassivi SD, Wigle D, Nichols FC, Blackmon S, Tapias LF, Callstrom MR, Owen D. Sublobar Resection, Stereotactic Body Radiation Therapy, and Percutaneous Ablation Provide Comparable Outcomes for Lung Metastasis-Directed Therapy. Chest. 2024 May; 165 (5):1247-1259 Epub 2023 Dec 14 View PubMed Kapplinger JD, Lima LMF, Packard AT, Nathan MA, Young JR, Stish BJ, Hough DM. Safety and Efficacy of CT-Guided Percutaneous Biopsy of Suspicious Subcentimeter Pelvic and Retroperitoneal Lymph Nodes Detected by (11)C-Choline PET in Patients With Prostate Cancer. AJR Am J Roentgenol. 2023 May; 220 (5):718-725 Epub 2022 Dec 07 View PubMed Clemens DJ, Lentino AR, Kapplinger JD, Ye D, Zhou W, Tester DJ, Ackerman MJ. Using the genome aggregation database, computational pathogenicity prediction tools, and patch clamp heterologous expression studies to demote previously published long QT syndrome type 1 mutations from pathogenic to benign. Heart Rhythm. 2018 Apr; 15 (4):555-561 Epub 2017 Dec 02 View PubMed Paquin A, Ye D, Tester DJ, Kapplinger JD, Zimmermann MT, Ackerman MJ. Even pore-localizing missense variants at highly conserved sites in KCNQ1-encoded Kv7.1 channels may have wild-type function and not cause type 1 long QT syndrome: Do not rely solely on the genetic test company's interpretation. HeartRhythm Case Rep. 2018 Feb; 4 (2):37-44 Epub 2017 Dec 11 View PubMed Kapplinger JD, Pundi KN, Larson NB, Callis TE, Tester DJ, Bikker H, Wilde AAM, Ackerman MJ. Yield of the RYR2 Genetic Test in Suspected Catecholaminergic Polymorphic Ventricular Tachycardia and Implications for Test Interpretation. Circ Genom Precis Med. 2018 Feb; 11 (2):e001424 View PubMed Baruteau AE, Tester DJ, Kapplinger JD, Ackerman MJ, Behr ER. Sudden infant death syndrome and inherited cardiac conditions. Nat Rev Cardiol. 2017 Dec; 14 (12):715-726 Epub 2017 Sept 07 View PubMed Anderson HN, Bos JM, Kapplinger JD, Meskill JM, Ye D, Ackerman MJ. Lidocaine attenuation testing: An in vivo investigation of putative LQT3-associated variants in the SCN5A-encoded sodium channel. Heart Rhythm. 2017 Aug; 14 (8):1173-1179 Epub 2017 Apr 13 View PubMed Yamagata K, Horie M, Aiba T, Ogawa S, Aizawa Y, Ohe T, Yamagishi M, Makita N, Sakurada H, Tanaka T, Shimizu A, Hagiwara N, Kishi R, Nakano Y, Takagi M, Makiyama T, Ohno S, Fukuda K, Watanabe H, Morita H, Hayashi K, Kusano K, Kamakura S, Yasuda S, Ogawa H, Miyamoto Y, Kapplinger JD, Ackerman MJ, Shimizu W. Genotype-Phenotype Correlation of SCN5A Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome: A Japanese Multicenter Registry. Circulation. 2017 Jun 6; 135 (23):2255-2270 Epub 2017 Mar 24 View PubMed Kapplinger JD, Erickson A, Asuri S, Tester DJ, McIntosh S, Kerr CR, Morrison J, Tang A, Sanatani S, Arbour L, Ackerman MJ. KCNQ1 p.L353L affects splicing and modifies the phenotype in a founder population with long QT syndrome type 1. J Med Genet. 2017 Jun; 54 (6):390-398 Epub 2017 Mar 06 View PubMed Ackerman JP, Bartos DC, Kapplinger JD, Tester DJ, Delisle BP, Ackerman MJ. The Promise and Peril of Precision Medicine: Phenotyping Still Matters Most. Mayo Clin Proc. 2016 Oct 8 Epub 2016 Oct 08 View PubMed Murphy SL, Anderson JH, Kapplinger JD, Kruisselbrink TM, Gersh BJ, Ommen SR, Ackerman MJ, Bos JM. Evaluation of the Mayo Clinic Phenotype-Based Genotype Predictor Score in Patients with Clinically Diagnosed Hypertrophic Cardiomyopathy. J Cardiovasc Transl Res. 2016 Apr; 9 (2):153-61 Epub 2016 Feb 25 View PubMed Van Driest SL, Wells QS, Stallings S, Bush WS, Gordon A, Nickerson DA, Kim JH, Crosslin DR, Jarvik GP, Carrell DS, Ralston JD, Larson EB, Bielinski SJ, Olson JE, Ye Z, Kullo IJ, Abul-Husn NS, Scott SA, Bottinger E, Almoguera B, Connolly J, Chiavacci R, Hakonarson H, Rasmussen-Torvik LJ, Pan V, Persell SD, Smith M, Chisholm RL, Kitchner TE, He MM, Brilliant MH, Wallace JR, Doheny KF, Shoemaker MB, Li R, Manolio TA, Callis TE, Macaya D, Williams MS, Carey D, Kapplinger JD, Ackerman MJ, Ritchie MD, Denny JC, Roden DM. Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records. JAMA. 2016 Jan 5; 315 (1):47-57 View PubMed Kapplinger JD, Giudicessi JR, Ye D, Tester DJ, Callis TE, Valdivia CR, Makielski JC, Wilde AA, Ackerman MJ. Enhanced Classification of Brugada Syndrome-Associated and Long-QT Syndrome-Associated Genetic Variants in the SCN5A-Encoded Na(v)1.5 Cardiac Sodium Channel. Circ Cardiovasc Genet. 2015 Aug; 8 (4):582-95 Epub 2015 Apr 22 View PubMed Kapplinger JD, Tseng AS, Salisbury BA, Tester DJ, Callis TE, Alders M, Wilde AA, Ackerman MJ. Enhancing the Predictive Power of Mutations in the C-Terminus of the KCNQ1-Encoded Kv7.1 Voltage-Gated Potassium Channel. J Cardiovasc Transl Res. 2015 Apr; 8 (3):187-97 Epub 2015 Apr 09 View PubMed Kapplinger JD, Landstrom AP, Bos JM, Salisbury BA, Callis TE, Ackerman MJ. Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise. J Cardiovasc Transl Res. 2014 Apr; 7 (3):347-61 Epub 2014 Feb 08 View PubMed Giudicessi JR, Kapplinger JD, Tester DJ, Alders M, Salisbury BA, Wilde AA, Ackerman MJ. Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome. Circ Cardiovasc Genet. 2012 Oct 1; 5 (5):519-28 Epub 2012 Sept 04 View PubMed Amin AS, Giudicessi JR, Tijsen AJ, Spanjaart AM, Reckman YJ, Klemens CA, Tanck MW, Kapplinger JD, Hofman N, Sinner MF, Muller M, Wijnen WJ, Tan HL, Bezzina CR, Creemers EE, Wilde AA, Ackerman MJ, Pinto YM. Variants in the 3' untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner. Eur Heart J. 2012 Mar; 33(6):714-23. Epub 2011 Dec 23. View PubMed Kapplinger JD, Landstrom AP, Salisbury BA, Callis TE, Pollevick GD, Tester DJ, Cox MG, Bhuiyan Z, Bikker H, Wiesfeld AC, Hauer RN, van Tintelen JP, Jongbloed JD, Calkins H, Judge DP, Wilde AA, Ackerman MJ. Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia-associated mutations from background genetic noise. J Am Coll Cardiol. 2011 Jun 7; 57 (23):2317-27 View PubMed Kapplinger JD, Tester DJ, Alders M, Benito B, Berthet M, Brugada J, Brugada P, Fressart V, Guerchicoff A, Harris-Kerr C, Kamakura S, Kyndt F, Koopmann TT, Miyamoto Y, Pfeiffer R, Pollevick GD, Probst V, Zumhagen S, Vatta M, Towbin JA, Shimizu W, Schulze-Bahr E, Antzelevitch C, Salisbury BA, Guicheney P, Wilde AA, Brugada R, Schott JJ, Ackerman MJ. An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. Heart Rhythm. 2010 Jan; 7 (1):33-46 Epub 2009 Oct 08 View PubMed Kapplinger JD, Tester DJ, Salisbury BA, Carr JL, Harris-Kerr C, Pollevick GD, Wilde AA, Ackerman MJ. Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test. Heart Rhythm. 2009 Sep; 6 (9):1297-303 Epub 2009 June 23 View PubMed Johnson NG, Mello RN, Lundy ME, Kapplinger JD, Parke E, Carnes KD, Ben-Itzhak I, Wells E. Single ionization of hydrogen molecules by fast protons as a function of the molecular alignment Physical Review A. 2005; 72(5):052711. PST-20573341 Home Publications