Sarosh R. Irani, B.M.B.Ch., D.Phil.

Summary. I am a neuroimmunologist with experiences and expertise in treating a broad range of patients with neurological diseases, especially those caused by dysfunction of the immune system.

Background. I graduated in medicine (BMBCh) from the University of Oxford, UK, and, from 2003-2006, completed my internal medicine training in both Oxford and London. Next, I completed a PhD in Clinical Neurology at Oxford University (DPhil) and, subsequently, undertook clinical residency training in neurology, in London and Oxford followed by a Fulbright Fellowship in multiple sclerosis and autoimmune neurology in UCSF, USA. Since 2014, I have practiced as a consultant neurologist in Oxford both caring for patients with general neurological conditions, and with a special focus on patients with autoimmune neurological illnesses. I founded the Oxford Autoimmune Neurology clinic and was promoted to full Professor of Autoimmune Neurology at the University of Oxford in 2021. I joined Mayo Clinic Florida in 2023.

Focus. I have extensive experience in diagnosing and managing a variety of neuroimmune conditions, including autoimmune encephalitis, neuromyelitis optica, stiff person syndrome and multiple sclerosis. I have cared for over 300 patients with LGI1, CASPR2, NMDA and GABA receptor-antibodies and seronegative forms of encephalitis, and am one of the world's most experienced clinicians in this area, and for around 10 years, ran the UK's main referral clinic for these patients.

Also, I help advise the Encephalitis Society and Autoimmune Encephalitis Alliance, two of the major foundations providing patient support in this field. In addition, I lead an internationally-recognized research group which has made several landmark discoveries including the detection of LGI1 and CASPR2 antibodies and their associated presentations, and published >150 scientific papers about autoimmune neurological diseases. I have been awarded multiple international prizes in recognition of my clinical and research observations.