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Gregory Frey, M.D.

  1. Radiologist
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Departments

Specialty Groups

  1. Vascular and Interventional Radiology

Location

  1. Jacksonville, Florida

Languages

English

Existing patients

Gregory Frey, M.D., M.P.H., is chair of the Division of Interventional Radiology at Mayo Clinic in Jacksonville, Florida, and an associate professor of radiology at Mayo Clinic College of Medicine and Science. Board certified in diagnostic radiology, vascular and interventional radiology, and interventional radiology/diagnostic radiology, Dr. Frey provides care for people in Jacksonville and surrounding areas using advanced, minimally invasive image-guided and endovascular therapies.

Dr. Frey's interventional oncology practice focuses on liver, renal, and prostate cancers, offering therapies that reduce procedure risk while maintaining precision. He previously served as program director for the integrated and independent interventional radiology residency programs, helping train the next generation of interventional radiologists.

Areas of expertise

Dr. Frey provides minimally invasive, image-guided therapies for cancer and vascular conditions. His areas of expertise include:

  • Primary liver cancer (hepatocellular carcinoma and cholangiocarcinoma): Liver-directed interventional treatments including radioembolization and image-guided tumor ablation
  • Renal and prostate cancer: MR-guided and image-guided therapies to minimize invasiveness while maintaining accuracy
  • Venous disease: Treatment of chronic venous disorders and venous insufficiency using catheter-based and endovascular approaches
  • Portal hypertension: Image-guided management of complex portal hypertension and its complications
  • Interventional oncology: Advanced image-guided and minimally invasive cancer care for patients seeking targeted treatment options

Research and expertise

Dr. Frey's research explores MR-guided interventional therapy, including MRI-guided prostate cancer treatment, liver-directed cancer therapy, image-guided tumor ablation, and venous interventions. His academic work reflects a dedication to advancing precision-based oncology and improving minimally invasive procedural outcomes.

As chair of the Division of Interventional Radiology at Mayo Clinic in Florida, Dr. Frey leads collaborative research and clinical innovation aimed at enhancing patient-centered care.

Personal note

Dr. Frey believes that patients deserve a clear understanding of their medical options so they can make informed decisions aligned with their goals.

"The path to choosing a treatment is not always straightforward. The risks and benefits of a therapy can vary from person to person and must be considered in the context of each patient's priorities. It is our duty to help patients understand these issues and identify therapies that ultimately fit their personal treatment goals."

Outside of his work, Dr. Frey enjoys cooking, traveling, fly fishing, and playing tennis.

  1. Uterine fibroid
  2. Venous insufficiency
  1. Chemoembolization
  2. Coronary angioplasty and stenting
  3. Cryoablation for cancer
  4. Endovenous thermal ablation
  5. Percutaneous valve procedure
  6. Radioembolization
  7. Radiofrequency ablation for cancer
  8. Radiofrequency neurotomy
  9. Uterine artery embolization
  • Percutaneous treatment of peripheral vascular disease
  • Interventional oncology including radiofrequency ablation, cryoablation, microwave ablation, chemoembolization and radioembolization
  • Venous disease/insufficiency and endovenous laser therapy
  • Uterine fibroid embolization
  • Percutaneous treatment of aortic pathology including aneurysmal disease and occlusive disease
  • Development of innovative and minimally invasive methods for percutaneous treatment of disease (vascular and regional organ therapy)
  1. 2011
    Fellow - Vascular Interventional RadiologyUniversity of Virginia
  2. 2010
    Resident - Diagnostic RadiologyEmory University
  3. 2006
    Resident - Internal MedicineThe Jewish Hospital
  4. 2005
    MDUniversity of Cincinnati
  5. 2001
    MPH - EpidemiologyGeorge Washington University
  6. 1998
    BS - ChemistryGeorgetown University

Certifications

  1. 2017
    Interventional Radiology and Diagnostic RadiologyAmerican Board of Radiology

Awards and honors

  1. 2015
    The Permanente Journal Service Quality AwardInstitute for Healthcare Improvement 27th Annual National Forum
  2. 2013
    Rotation of the Year, Interventional RadiologyRadiology Residency Program, Department of Radiology
  3. 2009
    J.T. Rutherford Government Relations FellowshipAmerican College of Radiology

Professional memberships

  1. 2021 - present
    CouncilorOfficers and Councilors
  2. 2019 - present
    Active MemberMayo Clinic Operations Coordinating Group
  3. 2018 - present
    Active MemberClinical Competency Committee
  4. 2018 - present
    Super UserEpic Superuser
  5. 2017 - present
    Subject Matter ExpertPlummer Project
  6. 2017 - present
    Physician AdvisorPlummer Project Physician Advisory Group
  7. 2016 - present
    MemberAssociation of Program Directors in Interventional Radiology
  8. 2016 - present
    MemberAssociation of Program Directors in Interventional Radiology
  9. 2015 - present
    MemberEnterprise Radiology IT Committee (formerly Mayo Clinic Radiology Information Technology Committee), Mayo Clinic Committees
  10. 2015 - 2019
    Active MemberMCF Hospital Practice Subcommittee
  11. 2015 - 2017
    CouncilorFlorida Radiologic Society
  12. 2014 - 2019
    Alternate CouncilorFlorida Radiological Society
  13. 2014 - present
    Active MemberSurgical and Procedural Committee
  14. 2013 - 2018
    Active MemberAutomated Radiology Practice Steering Committee, Department of Radiology
  15. 2013 - present
    MemberFlorida Radiological Society
  16. 2011 - present
    MemberSociety of Interventional Radiology
  17. 2009 - 2011
    MemberMembership Development Committee, American College of Radiology
  18. 2008 - 2011
    Resident RepresentativeCommittee on International Service, American College of Radiology
  19. 2008 - 2009
    Peer-Elected RepresentativeExecutive Committee, Resident and Fellow Section, American College of Radiology
  20. 2008 - 2009
    Resident PresidentGeorgia Radiological Society
  21. 2007 - 2010
    Resident RepresentativeGeorgia Radiological Society
  22. 2006 - present
    MemberAmerican College of Radiology
  23. 2006 - present
    MemberRadiological Society of North America
  24. 2006 - present
    MemberAmerican Roentgen Ray Society
  25. 2006 - 2010
    Resident RepresentativeAmerican College of Radiology
  26. 2003 - 2004
    Student RepresentativePromotions Board, Academic Standing and Academic Standards, University of Cincinnati College of Medicine
  27. 2002 - 2003
    Student RepresentativeMedical College Governing Body, Faculty Council, University of Cincinnati College of Medicine
  28. 2001 - 2005
    PresidentMedical Student Association, University of Cincinnati College of Medicine

Publications