Publications Print Shekhar S, Agrawal A, Almadhoun H, Wieruszewski PM, Mahalwar G, Kansara T, Nelson JA, Morozowich ST, Gil IN, Narasimhan S, Ramakrishna H, Elmadhoun O. Cardiogenic Shock: Current Evidence, Guideline Perspectives, and Outcomes. J Cardiothorac Vasc Anesth. 2026 Aug; 40 (8):2581-2598 Epub 2026 Jan 24 View PubMed Merren MP, Augustin K, Ripoll JG, Kinni HA, Vinzant N, Garcia SI, D'Andria Ursoleo J, Nabzdyk CG, Eauchai L, Ramakrishna H, Elmadhoun O. Resuscitative Point-of-Care Ultrasound in Cardiac Arrest: Current Evidence and Clinical Applications. J Cardiothorac Vasc Anesth. 2026 Jul 23 Epub 2026 July 23 View PubMed Sakusic A, Lee J, Seid KR, Ortoleva JP, Martin NJ, Vollmer NJ, Ramanujan KS, Wieruszewski PM, D'Andria Ursoleo J, Ding Y, Elmadhoun O. Neurological complications, neuromonitoring, and outcomes in extracorporeal membrane oxygenation: Venovenous versus venoarterial support – A comprehensive review Brain circulation. 2026. D'Andria Ursoleo J, Bugo S, Bottussi A, Wieruszewski PM, Guru PK, Seelhammer TG, Elmadhoun O. Bivalirudin in Pulmonary Embolism: A Contender Worth Attention. J Cardiothorac Vasc Anesth 2026 Jul; 40 (7):1933-1938 Epub 2026 Mar 24 View PubMed Mu C, Ding Y, Elmadhoun O, Li F, Geng X. Rapid Assessment of Stroke Severity: Development of a Visual Infarct and Comprehensive Scoring System in Ischemic Rats With Middle Cerebral Artery Occlusion. Eur J Neurosci. 2026 Jul; 64 (2):e70611 View PubMed Ding R, Elmadhoun O, Chen R, Ji X. Comprehensive strategies for stroke prevention: A narrative review of population-level risk factor mitigation. Brain Circ. 2026 Jul-Sep; 12 (3):226-245 Epub 2025 Oct 09 View PubMed Elmadhoun O, Balanescu DV, Seelhammer TG, Alwatari Y, Buda KG, Ortoleva JP, Ahmad SR, Chaudhary S, Ramanujan K, Guru PK, Caples SM, Wieruszewski PM, Ramakrishna H. The 2026 Multisociety Acute Pulmonary Embolism Guidelines: An Expert Perspective. J Cardiothorac Vasc Anesth. 2026 Jun 3 Epub 2026 June 03 View PubMed Sakusic A, Wieruszewski PM, Ortoleva JP, Elmadhoun O. Beyond Intravenous Vasopressors in the Intensive Care Unit: The Emerging Role of Droxidopa. J Cardiothorac Vasc Anesth 2026 Jun; 40 (6):1615-1618 Epub 2026 Feb 13 View PubMed Bugo S, Bottussi A, Wieruszewski ED, Ripoll JG, Elmadhoun O, Wieruszewski PM, D'Andria Ursoleo J. The Sibling Effect: Can Etomidate's Analogues Offer Better Anesthetic Induction for Cardiac Surgery? J Cardiothorac Vasc Anesth 2026 Jun; 40 (6):1609-1614 Epub 2026 Feb 12 View PubMed Elmadhoun O, Teixeira MT, Saddoughi SA, Fritz AV, Abutaka AG, Qamar Y, Nabzdyk CG, Combes A, Yalamuri SM, Ramakrishna H. The Contemporary Landscape of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation. J Cardiothorac Vasc Anesth. 2026 Jun; 40 (6):1891-1896 Epub 2025 Dec 13 View PubMed Merren MP, Feller D, Lange SB, Ahmad SR, Buda KG, Kor NT, Takahashi EA, Motiei A, Ursoleo JD, Nabzdyk CG, Caples SM, Elmadhoun O. Mechanical Thrombectomy for Intermediate- and High-Risk Pulmonary Embolism: A Retrospective Observational Cohort Study. J Intensive Care Med. 2026 May 28; 8850666261452151 [Epub ahead of print] View PubMed Huang S, Kong F, Zhao W, Ren C, Elmadhoun O, Ding Y, Ji X, Zhao Y, Li S. Remote ischemic conditioning for cerebral ischemia in patients with Takayasu arteritis (TARIC-1): Study protocol. Brain Circ. 2026 Apr-Jun; 12 (2):118-123 Epub 2026 Jan 12 View PubMed Elmadhoun O, Karadzha A, Kor NT, Almadhoun H, Ortoleva JP, Ripoll JG, Martin NJ, Nabzdyk CG, Wieruszewski PM, D'Andria Ursoleo J, Ramakrishna H. Biomarkers in Cardiogenic Shock: From Bench to Bedside. J Cardiothorac Vasc Anesth. 2026 Apr; 40 (4):1288-1301 Epub 2025 Nov 14 View PubMed Bottussi A, Wieruszewski PM, Bignami EG, Swol J, Buda KG, Cheungpasitporn W, Elmadhoun O, D'Andria Ursoleo J. Can algorithms come to the rescue of a failing heart? Machine learning, artificial intelligence, and decision-making in cardiogenic shock. J Anesth Analg Crit Care 2026 Mar 12; 6 (1) View PubMed Esmaeilzadeh S, Bittner EA, Chang MG, Ortoleva J, Pisano DV, Elmadhoun O, Wieruszewski PM, Ripoll JG. Stress-induced cardiomyopathy in the ICU. Best Pract Res Clin Anaesthesiol. 2026 Mar; 40 (1):41-54 Epub 2026 June 12 View PubMed Brinkman H, Ortoleva J, Elliott A, Pisano D, Ripoll J, Martin N, Seelhammer T, Kraybill M, Elmadhoun O, Bottussi A, Leone M, Wittwer E, D’Andria Ursoleo J, Wieruszewski P. Vasopressors and Inotropes during venoarterial extracorporeal membrane oxygenation Frontiers in Cardiovascular Medicine. 2026. Elmadhoun O, Esmaeilzadeh S, Teixeira MT, Huang J, Ramanujan K, Shaefi S, Ramakrishna H. Hyperoxia in Cardiac Surgery: Where Do We Stand? J Cardiothorac Vasc Anesth. 2026 Jan; 40 (1):372-382 Epub 2025 July 21 View PubMed Wang S, Wang J, Elmadhoun O, Liang Y, Zhao W. Advances in intracerebral hemorrhage management: A comprehensive review. Brain Circ. 2026 Jan-Mar; 12 (1):13-21 Epub 2025 June 09 View PubMed Ji Q, Mei S, Cai L, Elmadhoun O, Ding Y, Geng X. Role of prefrontal cortex in freezing of gait in Parkinson's disease: mechanisms and neuroimaging evidence. Front Neurol. 2026; 17:1713795 Epub 2026 Feb 17 View PubMed Wang X, Ding Y, Elmadhoun O, Yuan Y, Tong Y, Cai L, Ji Q, Wang Y, Li F, Geng X. Repeated lower extremities hot water bathing (REHAB), a rehabilitative strategy in Parkinson's disease (PD) patients with sleep disorders: rationale, design and protocol for a randomized controlled study. Front Neurol. 2026; 17:1753102 Epub 2026 Mar 24 View PubMed Bugo S, Bottussi A, D'Andria Ursoleo J, Antonini MV, Cordella E, Aprile M, Garcia SI, Elmadhoun O, Wieruszewski ED, Swol J, Wieruszewski PM, Monaco F. Contemporary extracorporeal cardiopulmonary resuscitation programs for cardiac arrest. Front Cardiovasc Med. 2026; 13:1761019 Epub 2026 July 08 View PubMed Labanca R, Ursoleo JD, Fresilli S, Bottussi A, Pontillo D, Elmadhoun O, Lodovici M, Bonaccorso A, Wieruszewski PM, Monaco F. Clevidipine versus nitroglycerin for blood pressure control during carotid endarterectomy: a cohort study. BMC Anesthesiol. 2025 Dec 15; 26 (1):45 View PubMed Ripoll JG, Kahn-Pascual YO, Seelhammer TG, Bittner EA, Chang MG, Ortoleva J, Diaz Soto JC, Elmadhoun O, Naoum EE, Wieruszewski PM, Nabzdyk CG, Ramakrishna H. ECMO in Pregnancy: Analysis of Indications, Management and Outcomes. J Cardiothorac Vasc Anesth. 2025 Dec; 39(12):3557-3575. Epub 2025 Aug 16. View PubMed Zhu Y, Li F, Elmadhoun O, Pang Q, Ding Y, Geng X. Critical role of translocator protein (TSPO) in neuronal mitochondrial dysfunction and mental stress-exacerbated ischemic injury following stroke. Transl Psychiatry. 2025 Dec 1; 16 (1):9 Epub 2025 Dec 01 View PubMed Elmadhoun O, Ramanujan K, Wieruszewski PM, Almadhoun H, Arboleda AL, Munoz-Acuna R, Cheungpasitporn W, Yalamuri SM, Ramakrishna H. Perioperative Acute Kidney Injury: What's New in 2025? J Cardiothorac Vasc Anesth. 2025 Oct 17 [Epub ahead of print] View PubMed Elmadhoun O, Merren MP, Wieruszewski PM, Ripoll JG, Huang J, Ramakrishna H. Pulmonary Embolism: Unanswered Questions and Ongoing Evidence Gaps. J Cardiothorac Vasc Anesth. 2025 Sep; 39 (9):2498-2505 Epub 2025 May 20 View PubMed Wang L, Huang S, Wang Y, Elmadhoun O, Ren C, Zhao W, Yu Y, Liu G, Ji X, Li S. Early Risk Prediction Model for Stroke-Heart Syndrome Following Endovascular Therapy. Aging Dis. 2025 Aug 1; 17 (5):2780-2790 Epub 2025 Aug 01 View PubMed Welker CC, Huang J, Elmadhoun O, Jacob AK, Ramakrishna H. Examining the Safety of Continuing Preoperative Renin-angiotensin System Inhibitors in Noncardiac Surgery. J Cardiothorac Vasc Anesth. 2025 Aug; 39 (8):2193-2197 Epub 2025 Mar 28 View PubMed Wang Y, He M, Wang L, Elmadhoun O, Liu F, Zhao W, Ren C, Ding Y, Ji X, Li S. Interaction between Brain Natriuretic Peptide and QTc Prolongation on Mortality in Patients with Stroke-Heart Syndrome. Aging Dis. 2025 Jul 31; 17 (5):2791-2803 Epub 2025 July 31 View PubMed Elmadhoun O, Esmaeilzadeh S, Merren MP, Ripoll JG, Wieruszewski PM, Ramakrishna H. Extracorporeal Membrane Oxygenation in Pulmonary Embolism: Current Evidence and Evolving Data. J Cardiothorac Vasc Anesth. 2025 Jun; 39 (6):1556-1563 Epub 2025 Mar 08 View PubMed Powell TE, Loftsgard TO, Abcejo AS, Elmadhoun O. Pulmonary Hemorrhage During Pulmonary Artery Stenting Necessitating Venovenous Extracorporeal Membrane Oxygenation. J Cardiothorac Vasc Anesth. 2025 Feb; 39 (2):489-491 Epub 2024 Nov 10 View PubMed Elmadhoun O, Huang J, Abcejo AS, Merren MP. Mechanical Thrombectomy for Acute Pulmonary Embolism in Non-Operating Room Anesthesia (NORA) Locations: Best Safety Practices and Local Insights. Healthcare (Basel). 2025 Jan 23; 13 (3) View PubMed Huang X, Ji Q, Tong T, Cai L, Elmadhoun O, Zeng Y, Geng X, Ding Y. Evaluating the safety and feasibility of remote ischemic conditioning for slowing cognitive decline in mild Alzheimer's dementia. Front Neurol. 2025; 16:1592829 Epub 2025 June 24 View PubMed Cheng Z, Wang H, Geng X, Rajah GB, Elmadhoun O, Peng G, Ding Y. Time and Tissue Windows in Futile Reperfusion after Ischemic Stroke. Aging Dis. 2024 Oct 21; 16 (5):2544-2552 View PubMed Merren MP, Padkins MR, Cajigas HR, Neidert NB, Abcejo AS, Elmadhoun O. Perioperative Management and Outcomes after Endovascular Mechanical Thrombectomy in Patients with Submassive (Intermediate-Risk) Pulmonary Embolism: A Retrospective Observational Cohort Study. Healthcare (Basel). 2024 Aug 27; 12 (17) View PubMed Welker C, Huang J, Elmadhoun O, Esmaeilzadeh S, Mookadam F, Ramakrishna H. Morbidity Following Pulmonary Embolism Hospitalization- Contributing Factors and Outcomes. J Cardiothorac Vasc Anesth. 2024 May; 38 (5):1239-1243 Epub 2024 Feb 07 View PubMed Laudanski K, Elmadhoun O, Mathew A, Kahn-Pascual Y, Kerfeld MJ, Chen J, Sisniega DC, Gomez F. Anesthetic Considerations for Patients with Hereditary Neuropathy with Liability to Pressure Palsies: A Narrative Review. Healthcare (Basel). 2024 Apr 19; 12(8). View PubMed Calhoun A, Pannu A, Mueller AL, Elmadhoun O, Valencia JD, Krajewski ML, O'Gara BP, Katsiampoura A, O'Connor ST, Chu L, Monteith E, Shankar P, Spear K, Shaefi S. Intraoperative Oxygen Practices in Cardiac Surgery: A National Survey. J Cardiothorac Vasc Anesth. 2022 Aug; 36 (8 Pt B):2917-2926 Epub 2022 Jan 19 View PubMed An H, Zhao W, Wang J, Wright JC, Elmadhoun O, Wu D, Shang S, Wu C, Li C, Wu L, Chen J, Duan J, Zhang H, Song H, Ding Y, Ji X. Contrast Staining may be Associated with Intracerebral Hemorrhage but Not Functional Outcome in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy. Aging Dis. 2019 Aug; 10 (4):784-792 Epub 2019 Aug 01 View PubMed Ding J, Zhou D, Hu Y, Elmadhoun O, Pan L, Ya J, Geng T, Wang Z, Ding Y, Ji X, Meng R. The efficacy and safety of Batroxobin in combination with anticoagulation on cerebral venous sinus thrombosis. J Thromb Thrombolysis. 2018 Oct; 46(3):371-378. View PubMed Zhang J, Liu K, Elmadhoun O, Ji X, Duan Y, Shi J, He X, Liu X, Wu D, Che R, Geng X, Ding Y. Synergistically Induced Hypothermia and Enhanced Neuroprotection by Pharmacological and Physical Approaches in Stroke. Aging Dis. 2018 Aug; 9 (4):578-589 Epub 2018 Aug 01 View PubMed Guo S, Elmadhoun O, Ding Y. Mental stress studies in animals Environmental Disease. 2018; vol. 3(no. 2):p. 29. Geng X, Li F, Yip J, Peng C, Elmadhoun O, Shen J, Ji X, Ding Y. Neuroprotection by Chlorpromazine and Promethazine in Severe Transient and Permanent Ischemic Stroke. Mol Neurobiol. 2017 Dec; 54 (10):8140-8150 Epub 2016 Nov 28 View PubMed Geng X, Li F, Yip J, Peng C, Elmadhoun O, Shen J, Ji X, Ding Y. Erratum to: Neuroprotection by Chlorpromazine and Promethazine in Severe Transient and Permanent Ischemic Stroke. Mol Neurobiol. 2017 Dec; 54 (10):8151 View PubMed Wu D, Shi J, Elmadhoun O, Duan Y, An H, Zhang J, He X, Meng R, Liu X, Ji X, Ding Y. Dihydrocapsaicin (DHC) enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat. Brain Res. 2017 Sep 15; 1671:18-25 Epub 2017 July 03 View PubMed An H, Duan Y, Wu D, Yip J, Elmadhoun O, Wright JC, Shi W, Liu K, He X, Shi J, Jiang F, Ji X, Ding Y. Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke. Sci Rep. 2017 Aug 7; 7 (1):7469 Epub 2017 Aug 07 View PubMed Fan L, Su Y, Elmadhoun OA, Zhang Y, Zhang Y, Gao D, Ye H, Chen W. Protocol-directed weaning from mechanical ventilation in neurological patients: a randomised controlled trial and subgroup analyses based on consciousness. Neurol Res. 2015 Nov; 37 (11):1006-14 Epub 2015 Aug 27 View PubMed Dong J, Elmadhoun O, Ma X. Aetiological diagnosis of middle-aged and elderly cryptogenic ischaemic cerebral vascular disease. Neurol Res. 2015 Aug; 37 (8):744-9 Epub 2015 May 25 View PubMed Geng X, Elmadhoun O, Peng C, Ji X, Hafeez A, Liu Z, Du H, Rafols JA, Ding Y. Ethanol and normobaric oxygen: novel approach in modulating pyruvate dehydrogenase complex after severe transient and permanent ischemic stroke. Stroke. 2015 Feb; 46 (2):492-9 Epub 2015 Jan 06 View PubMed Parmar S, Moore-Langston S, Fredrickson V, Kim JM, Rastogi R, Elmadoun O, Ding Y. Neuroprotective mechanisms of oxygen and ethanol: a potential combination therapy in stroke. Curr Med Chem. 2015; 22(10):1194-204. View PubMed Hafeez A, Elmadhoun O, Peng C, Ding JY, Geng X, Guthikonda M, Ding Y. Reduced Apoptosis by Ethanol and Its Association with PKC-delta and Akt Signaling in Ischemic Stroke. Aging Dis. 2014 Dec; 5 (6):366-72 Epub 2014 Mar 08 View PubMed Lee SJ, Meng H, Elmadhoun O, Blaivas M, Wang MM. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication. Arch Neurol. 2011 Dec; 68 (12):1584-6 View PubMed PST-20568528 Home Publications