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Xiaoning Ding, Ph.D.

  1. Radiation Oncology Medical Physicist

Publications

  1. Ding X, Zhang Y, Huang T, Xu G, Peng C, Chen G, Kong B, Friess H, Shen S, Lv Y, Roberts LR, Wang L, Zou X. Erratum: Targeting sphingosine kinase 2 suppresses cell growth and synergizes with BCL2/BCL-XL inhibitors through NOXA-mediated MCL1 degradation in cholangiocarcinoma. Am J Cancer Res. 2023; 13 (11):5746-5747 Epub 2023 Nov 15
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  2. Ding X, Younkin JE, Shen J, Bues M, Liu W. A critical review of the practices of proton daily quality assurance programs. Ther Radiol Oncol. 2021 Dec; 5:22.
  3. Kang Y, Shen J, Bues M, Hu Y, Liu W, Ding X. Technical Note: Clinical modeling and validation of breast tissue expander metallic ports in a commercial treatment planning system for proton therapy. Med Phys. 2021 Nov; 48 (11):7512-7525 Epub 2021 Sept 24
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  4. Younkin JE, Robertson DG, Liu W, Hu Y, Morales DH, Bues M, Shen J, Ding X. Technical Note: Long-term monitoring of diode sensitivity degradation induced by proton irradiation. Med Phys. 2021 Nov; 48 (11):6634-6641 Epub 2021 Oct 26
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  5. Younkin JE, Morales DH, Shen J, Ding X, Stoker JB, Yu NY, Sio TT, Daniels TB, Bues M, Fatyga M, Schild SE, Liu W. Technical Note: Multiple energy extraction techniques for synchrotron-based proton delivery systems may exacerbate motion interplay effects in lung cancer treatments. Med Phys. 2021 Sep; 48 (9):4812-4823 Epub 2021 July 29
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  6. Hu Y, Ding X, Shen J, Bues M, Liu W, Kang Y, Leng S, Yu L. Feasibility of using megavoltage computed tomography to reduce proton range uncertainty: A simulation study. J Appl Clin Med Phys. 2021 Mar; 22 (3):131-140 Epub 2021 Feb 20
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  7. Deng W, Younkin JE, Souris K, Huang S, Augustine K, Fatyga M, Ding X, Cohilis M, Bues M, Shan J, Stoker J, Lin L, Shen J, Liu W. Technical Note: Integrating an open source Monte Carlo code "MCsquare" for clinical use in intensity-modulated proton therapy. Med Phys. 2020 Jun; 47 (6):2558-2574 Epub 2020 Apr 13
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  8. Liu C, Patel SH, Shan J, Schild SE, Vargas CE, Wong WW, Ding X, Bues M, Liu W. Robust Optimization for Intensity Modulated Proton Therapy to Redistribute High Linear Energy Transfer from Nearby Critical Organs to Tumors in Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2020 May 1; 107 (1):181-193 Epub 2020 Jan 25
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  9. Deng W, Ding X, Younkin JE, Shen J, Bues M, Schild SE, Patel SH, Liu W. Hybrid 3D analytical linear energy transfer calculation algorithm based on precalculated data from Monte Carlo simulations. Med Phys. 2020 Feb; 47 (2):745-752 Epub 2019 Dec 10
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  10. Shen J, Ding X, Hu Y, Kang Y, Liu W, Deng W, Bues M. Technical Note: Comprehensive evaluation and implementation of two independent methods for beam monitor calibration for proton scanning beam. Med Phys. 2019 Dec; 46 (12):5867-5875 Epub 2019 Oct 31
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  11. Liu C, Yu NY, Shan J, Bhangoo RS, Daniels TB, Chiang JS, Ding X, Lara P, Patrick CL, Archuleta JP, DeWees T, Hu Y, Schild SE, Bues M, Sio TT, Liu W. Technical Note: Treatment planning system (TPS) approximations matter - comparing intensity-modulated proton therapy (IMPT) plan quality and robustness between a commercial and an in-house developed TPS for nonsmall cell lung cancer (NSCLC). Med Phys. 2019 Nov; 46 (11):4755-4762 Epub 2019 Sept 21
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  12. Liu C, Bhangoo RS, Sio TT, Yu NY, Shan J, Chiang JS, Ding JX, Rule WG, Korte S, Lara P, Ding X, Bues M, Hu Y, DeWees T, Ashman JB, Liu W. Dosimetric comparison of distal esophageal carcinoma plans for patients treated with small-spot intensity-modulated proton versus volumetric-modulated arc therapies. J Appl Clin Med Phys. 2019 Jul; 20 (7):15-27 Epub 2019 May 21
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  13. Kang Y, Shen J, Liu W, Taylor PA, Mehrens HS, Ding X, Hu Y, Tryggestad E, Keole SR, Schild SE, Wong WW, Fatyga M, Bues M. Impact of planned dose reporting methods on Gamma pass rates for IROC lung and liver motion phantoms treated with pencil beam scanning protons. Radiat Oncol. 2019 Jun 17; 14 (1):108 Epub 2019 June 17
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  14. Younkin JE, Morales DH, Shen J, Shan J, Bues M, Lentz JM, Schild SE, Stoker JB, Ding X, Liu W. Clinical Validation of a Ray-Casting Analytical Dose Engine for Spot Scanning Proton Delivery Systems. Technol Cancer Res Treat. 2019 Jan-Dec; 18:1533033819887182
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  15. Liu C, Sio TT, Deng W, Shan J, Daniels TB, Rule WG, Lara PR, Korte SM, Shen J, Ding X, Schild SE, Bues M, Liu W. Small-spot intensity-modulated proton therapy and volumetric-modulated arc therapies for patients with locally advanced non-small-cell lung cancer: A dosimetric comparative study. J Appl Clin Med Phys. 2018 Nov; 19 (6):140-148 Epub 2018 Oct 17
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  16. Younkin JE, Bues M, Sio TT, Liu W, Ding X, Keole SR, Stoker JB, Shen J. Multiple energy extraction reduces beam delivery time for a synchrotron-based proton spot-scanning system. Adv Radiat Oncol. 2018 Jul-Sep; 3 (3):412-420 Epub 2018 Feb 23
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  17. Liu C, Schild SE, Chang JY, Liao Z, Korte S, Shen J, Ding X, Hu Y, Kang Y, Keole SR, Sio TT, Wong WW, Sahoo N, Bues M, Liu W. Impact of Spot Size and Spacing on the Quality of Robustly Optimized Intensity Modulated Proton Therapy Plans for Lung Cancer. Int J Radiat Oncol Biol Phys. 2018 Jun 1; 101 (2):479-489 Epub 2018 Feb 14
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  18. Younkin JE, Shen J, Bues M, Robertson DG, Mundy DW, Clouser E, Liu W, Ding X, Stoker JB. Technical Note: An efficient daily QA procedure for proton pencil beam scanning. Med Phys. 2018 Mar; 45 (3):1040-1049 Epub 2018 Feb 19
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  19. An Y, Shan J, Patel SH, Wong W, Schild SE, Ding X, Bues M, Liu W. Robust intensity-modulated proton therapy to reduce high linear energy transfer in organs at risk. Med Phys. 2017 Dec; 44 (12):6138-6147 Epub 2017 Oct 26
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  20. Ding X, Liu W, Shen J, Anand A, Stoker JB, Hu Y, Bues M. Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation. J Appl Clin Med Phys. 2017 Nov; 18 (6):88-96 Epub 2017 Sept 18
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  21. Zheng Y, Ding X. Inter-Observer Variability of a Commercial Patient Positioning and Verification System in Proton Therapy. J Radiol Oncol. 2017; 1:031-038.
  22. Liu W, Schild SE, Chang JY, Liao Z, Chang YH, Wen Z, Shen J, Stoker JB, Ding X, Hu Y, Sahoo N, Herman MG, Vargas C, Keole S, Wong W, Bues M. Exploratory Study of 4D versus 3D Robust Optimization in Intensity Modulated Proton Therapy for Lung Cancer. Int J Radiat Oncol Biol Phys. 2016 May 1; 95 (1):523-533 Epub 2015 Nov 10
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  23. Liengsawangwong P, Sahoo N, Ding X, Lii M, Gillin MT, Zhu XR. Dosimetric Characteristics of a Two-Dimensional Diode Array Detector Irradiated with Passively Scattered Proton Beams. Cancers (Basel). 2015 Jul 30; 7 (3):1425-35 Epub 2015 July 30
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  24. Shen J, Liu W, Anand A, Stoker JB, Ding X, Fatyga M, Herman MG, Bues M. Impact of range shifter material on proton pencil beam spot characteristics. Med Phys. 2015 Mar; 42 (3):1335-40
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  25. Ding X, Zheng Y, Zeidan O, Mascia A, Hsi W, Kang Y, Ramirez E, Schreuder N, Harris B. A novel daily QA system for proton therapy. J Appl Clin Med Phys. 2013; 14(2):4058. Epub 2013 Mar 04.
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  26. Zheng Y, Ramirez E, Mascia A, Ding X, Okoth B, Zeidan O, Hsi W, Harris B, Schreuder AN, Keole S. Commissioning of output factors for uniform scanning proton beams. Med Phys. 2011 Apr; 38(4):2299-306.
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  27. Li F, Liu P, Liu C, Xiang D, Deng L, Li W, Wangensteen K, Song J, Ma Y, Hui L, Wei L, Li L, Ding X, Hu Y, He Z, Wang X. Hepatoblast-like progenitor cells derived from embryonic stem cells can repopulate livers of mice. Gastroenterology. 2010 Dec; 139 (6):2158-2169.e8 Epub 2010 Aug 27
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  28. Yang JN, Ding X, Du W, Pino R. Model-based calculations of off-axis ratio of conic beams for a dedicated 6 MV radiosurgery unit. Med Phys. 2010 Oct; 37(10):5442-7.
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  29. Arjomandy B, Sahoo N, Zhu XR, Zullo JR, Wu RY, Zhu M, Ding X, Martin C, Ciangaru G, Gillin MT. An overview of the comprehensive proton therapy machine quality assurance procedures implemented at The University of Texas M. D. Anderson Cancer Center Proton Therapy Center-Houston. Med Phys. 2009 Jun; 36 (6):2269-82
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  30. Arjomandy B, Sahoo N, Ding X, Gillin M. Use of a two-dimensional ionization chamber array for proton therapy beam quality assurance. Med Phys. 2008 Sep; 35(9):3889-94.
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  31. Titt U, Sahoo N, Ding X, Zheng Y, Newhauser WD, Zhu XR, Polf JC, Gillin MT, Mohan R. Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions. Phys Med Biol. 2008 Aug 21; 53(16):4455-70. Epub 2008 Jul 31.
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  32. Newhauser WD, Ding X, Giragosian D, Nill S, Titt U. Neutron radiation area monitoring system for proton therapy facilities. Radiat Prot Dosimetry. 2005; 115(1-4):149-53.
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  33. Farmer JW, Ding X, Cowan DL, Bradford DC. Cooperative flux pinning in single crystals of YBa2Cu3O7- delta. Phys Rev B Condens Matter. 1996 Jul 1; 54(1):637-43.
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  34. Pickup S, Ding X. Pulses with fixed magnitude and variable phase response profiles. Magn Reson Med. 1995 May; 33 (5):648-55
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  35. Farmer JW, Cowan DL, Ding X, Bradford D. Flux Creep in Twinned, Untwinned and Neutron Irradiated YBa2Cu3O7 Single Crystals. Physica C. 1994; 2893:C235-240.
PST-20324939