D Chamil Codipilly, M.D.

Don C. Codipilly, M.D., is a gastroenterologist at Mayo Clinic in Rochester, Minnesota, caring for people with complex esophageal and gastrointestinal conditions. Dr. Codipilly specializes in advanced endoscopic therapies and focuses on bringing evidence-based, personalized solutions to individuals with conditions such as Barrett's esophagus, early esophageal cancer, and complex strictures. His approach helps patients navigate the wide range of available information while ensuring the safest, most effective outcomes for every condition managed.

"My goal is to facilitate patient views while providing the highest quality, evidence-based care to ensure successful outcomes no matter what disease we are managing." — Dr. Codipilly

Areas of expertise

Dr. Codipilly delivers individualized care using advanced diagnostic and therapeutic approaches, including:

• Dysplastic Barrett's esophagus and early esophageal cancer: Diagnosis and endoscopic treatment with resection and ablation techniques, particularly radiofrequency ablation and cryotherapy as well as multidisciplinary care planning
• Gastroesophageal reflux disease (GERD): Evaluation and management of reflux and related complications
• Refractory esophageal strictures: Advanced endoscopic dilation and targeted therapies
• EndoFLIP diagnostics: Functional testing for esophageal physiology and procedural planning
• Colonoscopy and complex polypectomy: Endoscopic removal of challenging or high-risk polyps

Research and professional highlights

Dr. Codipilly is board-certified in internal medicine and gastroenterology. He serves as Assistant Professor of Medicine at Mayo Clinic College of Medicine and Science and is recognized with multiple honors, including the Mayo Brothers Distinguished Fellow Award and Shirley and Miles Fiterman Award for teaching and professionalism. His research focuses on applying artificial intelligence to improve diagnosis in Barrett's esophagus and leveraging technology for outcome optimization in endoscopic therapies.

Personal note

Outside of his work, Dr. Codipilly enjoys spending time with his wife and young son, playing basketball, running, and tinkering with his car.