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Kenneth D. Aldape, M.D.

  1. Pathologist
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Publications

  1. Jones AV, Lopes MBS, Patel SH, Asthagiri A, Abullaev Z, Aldape K, Fadul C, McCord M. Intracranial solitary fibrous tumor with myxoid features: An unusual presentation. J Neuropathol Exp Neurol. 2026 Mar 6 Epub 2026 Mar 06
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  2. Chakraborty D, Donnelly LL, Lefferts JA, Green DC, Shannon PM, Quezado M, Abdullaev Z, Aldape KD, Lin CC. A novel out-of-frame CREBBP::TRAP1 fusion in malignant intracerebral nerve sheath tumor. J Neuropathol Exp Neurol. 2026 Mar 2 Epub 2026 Mar 02
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  3. Gandhi S, Ahmadian S, Buckle P, Largaespada DA, Aldape K, Mansouri S, Zadeh G. A new framework for engaging patients and the public in basic cancer research. Nat Rev Cancer. 2026 Mar; 26 (3):162-163
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  4. Zhu Y, Ida CM, Schwartz JD, Zepeda-Mendoza CJ, Vizcaino Villalobos MA, Vaubel R, Raghunathan A, Miller KJ, Kaufmann T, Aldape KD, Giannini C. Dysembryoplastic neuroepithelial tumor: Malignant transformation following radiation. J Neuropathol Exp Neurol. 2026 Feb 14 [Epub ahead of print]
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  5. Fernandes IL, Abdullaev Z, Quezado M, Aldape K, Bacchi CE. Molecular Classification of Central Nervous System Tumors in Developing Countries: Challenges, Opportunities, and Feasibility in a Pathology Reference Laboratory. Arch Pathol Lab Med. 2026 Feb 11 [Epub ahead of print]
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  6. Trejo-Lopez JA, Mendoza CZ, Kollmeyer TM, Drucker KL, Pazdernik VM, Decker PA, Praska CE, Hardcastle J, Smoley S, Isaacson M, Gandham M, Dasari S, Raghunathan A, Giannini C, Zheng G, Wagner A, Lopes MB, Fung KA, Peterson JG, Rivera AL, Rossi C, Walsh MA, Abdullaev Z, Aldape K, Quezado M, Pratt D, Cimino PJ, Jenkins RB, Ida CM. Integrated high-resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34-mutant reveals universal TP53 abnormalities. Brain Pathol. 2026 Feb 6; e70076 Epub 2026 Feb 06
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  7. Ellenbogen Y, Patil V, Landry AP, Yefet LS, Wang JZ, Ajisebutu A, Gui C, Liu J, Persaud P, Aldape KD, Nassiri F, Zadeh G. Molecular classification of radiation-induced meningiomas. Int J Radiat Biol. 2026 Feb 2; 1-7 Epub 2026 Feb 02
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  8. Landry AP, Wang JZ, Patil V, Ajisebutu A, Gui C, Yefet LS, Ellenbogen Y, Liu J, Mamatjan Y, Wei Q, Singh O, Mansouri S, Ehret F, Capper D, Cohen-Gadol AA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chambless LB, Mansouri A, Makarenko S, Yip S, Tsang DS, Gao A, Aldape K, Nassiri F, Zadeh G, International Consortium On Meningiomas (ICOM)). A framework for using DNA methylation-based modelling for the clinical management of cranial meningioma. Neuro Oncol. 2026 Feb 1; 28 (2):430-439
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  9. Lalchungnunga H, Dampier CH, Singh O, Hoang DT, Shulman ED, Abdullaev Z, Li B, Luo Z, Wu Z, Pearce TM, Marker DF, McCortney K, Horbinski C, Lucas CG, Cimino PJ, Nasrallah MP, Quezado M, Chung HJ, Yefet L, Zadeh G, Brandner S, Ruppin E, Aldape K. Classification accuracy of a hierarchical molecular inference-based deep-learning system for CNS tumour diagnosis: a multi-institutional, retrospective study. Lancet Oncol. 2026 Feb; 27 (2):243-253
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  10. Rajan S, Chung HJ, Wu Z, Singh O, Dazelle K, Abdullaev Z, Tyagi M, Ferrone CK, Raffeld M, Lee I, Gagan J, Chen J, Cathcart S, Giannini C, Nguyen A, Gokden M, Perry A, Fernandes IL, Putnam AR, Kurek K, Green RM, Eberhart C, Lucas CH, Gonzalez-Gomez I, Lopez GY, Jones K, Prayson R, Yeaney G, Dermawan JKT, Chkheidze R, Appin C, Uhlmann EJ, Taliansky A, Blessing M, Mohila C, Cotter J, Deisch J, Andreiuolo F, Crawford JR, Mount C, Stemmer-Rachamimov AO, Lakis NS, Schmidt R, Chacko G, Newbury R, Neill S, Morales B, Fecher R, Sloan EA, Solomon DA, Nasrallah M, Quezado M, Fonseca A, Aldape K. Intracranial mesenchymal tumor, FET::CREB fusion-positive: an integrative analysis of 81 cases. Neuro Oncol. 2026 Jan 22 [Epub ahead of print]
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  11. Lochner RH, Powell SZ, Fung KM, Zhang YJ, Baskin D, Tremont-Lukats IW, Desai R, Dunn IF, Battiste JD, Hrachova M, Hardcastle J, Nazem A, Smoley SA, Isaacson M, Dasari S, Gandham M, Cimino PJ, Quezado M, Abdullaev Z, Pratt D, Aldape K, Jenkins R, Ida CM. FGFR1 fusions in genomically and epigenetically bona fide glioblastoma, IDH-wildtype. J Neuropathol Exp Neurol. 2026 Jan 1; 85 (1):98-102
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  12. van den Bent MJ, Ghisai SA, Wick W, Sanson M, Brandes AA, Clement PM, Erridge SC, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Tabouret E, Gill S, Griffin M, Taal W, Ruda R, Weller M, McBain C, Reijneveld JC, Enting RH, Tran S, Lesimple T, Kocher M, Gijtenbeek A, Lim E, Herrlinger U, Hau P, Dhermain F, Aldape K, Jenkins RB, Dubbink HJ, Kros JM, Wesseling P, Hoogstrate Y, Nuyens S, Golfinopoulos V, Tesileanu CMS, Gorlia T, French P, Baumert BG. Concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): final and exploratory analyses of a randomised, open-label, phase 3 trial. Lancet Oncol. 2026 Jan; 27 (1):45-56
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  13. Ospina-Romero M, Raza SM, Shah K, Quezado M, Aldape K, Gubbiotti MA. Expanding the differential diagnosis for dural-based spindle cell neoplasms: A report of a rare GLI1-altered mesenchymal tumor of the CNS. J Neuropathol Exp Neurol. 2026 Jan 1; 85 (1):103-105
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  14. Alfattal R, Nagarajan P, O'Brien B, Quezado M, Aldape K, Ballester LY, Gubbiotti MA. A Case of a Fumarate Hydratase Deficient Astrocytoma in Association With a Germline Fumarate Hydratase Mutation With Review of the Literature: Considerations for Patients With Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Syndrome. Am J Surg Pathol. 2026 Jan 1; 50 (1):132-137 Epub 2025 Aug 11
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  15. Munoz DG, Das S, Yoon JY, Siddaway R, Levine A, Aldape KD. Central nervous system schwannoma, VGLL-fused (EWSR1::VGLL1 fusion) with neuroblastoma-like cell dense areas in the frontal lobe of a young man with schwannomatosis due to a germline LZTR1 mutation. Free Neuropathol. 2026; 7:1 Epub 2026 Jan 08
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  16. Caliskan I, Costa FD, Jelsma P, Panda I, Mohamed R, Aldape K, Mirchia K, Pekmezci M, Perry A. Myxoid glioneuronal tumors can harbor unusual PDGFRA alterations. J Neuropathol Exp Neurol. 2025 Dec 31 [Epub ahead of print]
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  17. Pai EL, Nazarian MN, Kenyon AL, Abdullaev Z, Arisi M, Johnson ES, Surrey LF, Quezado M, Schwartz LE, Dumoff KL, Cooper K, Aldape K, Kenyon L, Nasrallah MP, Desai AS. Longitudinal neuropathologic and molecular characterization of a retroperitoneal ependymoma. J Neuropathol Exp Neurol. 2025 Dec 23 [Epub ahead of print]
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  18. Federico A, Schmitt-Hoffner F, Fonseca A, Geisemeyer N, Bruckner K, Mauermann M, Sill M, Stichel D, Sturm D, Schuller U, Tauziede-Espariat A, Varlet P, Capper D, Abdullaev Z, Schrimpf D, Selt F, Williamson L, Donson AM, Antonelli M, Miele E, Snuderl M, Brandner S, Lastowska M, Van Der Lugt J, Bunt J, Kramm C, Kolenova A, Raghunathan A, Wilson Y, Weintraub L, Hansford JR, Spiegl-Kreinecker S, Aistleitner B, Baroni L, Zapotocky M, Ramaswamy V, Korshunov A, Jones B, Kjaersgaard M, Kranendonk ME, Haberler C, Packer RJ, Jager N, Deimling AV, Sahm F, Koster J, Aldape K, Pfister SM, Hoff KV, Gojo J, Kool M. Molecular and Clinical Stratification of Astroblastomas: Three distinct Fusion-Defined Groups Informing Risk-Adapted Treatment Strategies. Neuro Oncol. 2025 Dec 22 [Epub ahead of print]
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  19. Hoang DT, Shulman ED, Dhruba SR, Nair NU, Barman RK, Cantore T, Biswas S, Lalchungnunga H, Singh O, Chung Y, Lee JS, Nasrallah MP, Stone EA, Aldape K, Ruppin E. Path2Omics Enhances Transcriptomic and Methylation Prediction Accuracy from Tumor Histopathology. Cancer Res. 2025 Dec 15; 85 (24):5098-5112
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  20. Matsumoto Y, Singh O, Garcia J, Abdullaev Z, Freeburg NF, Yu F, Akbari H, Baik K, Guo J, Shih NNC, Toorens E, Ganguly T, Ballinger D, O'Rourke DM, Mohan S, Morrissette JJD, Silverbush D, Aldape K, Davatzikos C, Nasrallah MP. Intratumoral preservation of the stem-like malignant cell proportion in glioblastoma, prognostic impact, and its radiomethylomic signatures. Neuro Oncol. 2025 Dec 1; 27 (12):3200-3213
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  21. Huynh V, Zhang D, Raghunathan A, Hardcastle J, Smoley S, Isaacson M, Gandham M, Dasari S, Abdullaev Z, Aldape K, Quezado M, Pratt D, Cimino PJ, Lachance D, Ida CM. SLC44A1::PRKCA fusion-positive glioneuronal tumor without histological and epigenetic features of papillary glioneuronal tumor. J Neuropathol Exp Neurol. 2025 Nov 12 [Epub ahead of print]
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  22. Yefet LS, Landry AP, Wang JZ, Liu J, Patil V, Gui C, Ajisebutu A, Ellenbogen Y, Mamatjan Y, Yakubov R, Kaloti R, Persaud P, Wei Q, Singh O, Mansouri S, Bunda S, Cohen-Gadol AA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chotai S, Chambless LB, Mansouri A, Agnihotri S, Makarenko S, Yip S, Tsang DS, Aldape K, Gao A, Nassiri F, Zadeh G. Assessment of Molecular Tools in Pediatric, Adolescent and Young Adult Meningioma Highlights the Need for Lifespan Precision in Neuro-Oncology. Neuro Oncol. 2025 Nov 8 Epub 2025 Nov 08
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  23. Wen PY, Weller M, Lee EQ, Touat M, Khasraw M, Rahman R, Platten M, Lim M, Winkler F, Horbinski C, Verhaak RGW, Huang RY, Ahluwalia MS, Albert NL, Tonn JC, Schiff D, Barnholtz-Sloan JS, Ostrom Q, Aldape KD, Batchelor TT, Bindra RS, Chiocca EA, Cloughesy TF, DeGroot JF, French P, Galanis E, Galldiks N, Gilbert MR, Hegi ME, Lassman AB, Le Rhun E, Mehta MP, Mellinghoff IK, Minniti G, Roth P, Sanson M, Taphoorn Andreas MJB, Weiss VDT, Wick W, Zadeh G, Reardon DA, Chang SM, Short SC, van den Bent MJ, Preusser M. Glioblastoma in adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions. Neuro Oncol. 2025 Nov 1; 27 (11):2751-2788
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  24. Huynh V, Vizcaino MA, Schwartz JD, Wilson JZ, Daniels DJ, Guerin JB, Kipp BR, Orr BA, Aldape K, Zhu Y. A posterior fossa mass in a 4-year-old female. Brain Pathol. 2025 Nov; 35 (6):e70028 Epub 2025 June 24
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  25. Cook DJ, Decker PA, Hardcastle JJ, Kollmeyer TM, Smoley SA, Isaacson MD, Gandham M, Dasari S, Abdullaev Z, Aldape K, Quezado M, Cimino PJ, Pratt DW, Giannini C, Nguyen A, Raghunathan A, Trejo-Lopez JA, Vaubel RA, Vizcaino MA, Mendoza CJZ, Al Kateb H, Jenkins RB, Ida CM. EGFR transcript variants: Potential diagnostic biomarker for glioblastoma, IDH-wildtype? J Neuropathol Exp Neurol. 2025 Nov 1; 84 (11):1059-1062
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  26. Chlopek M, Lasota J, Singh O, Blakely AM, Glod J, Ylaya K, Kaczorowski M, Klubickova N, Szumera-Cieckiewicz A, Rutkowski P, Michal M, Abdullaev Z, Aldape KD, Miettinen M. DNA Methylation Profiling Separates SDH-Deficient GISTs From KIT-PDGFRA-Driven GISTs and Identifies Predictive Biomarkers for Targeted Therapy. Am J Surg Pathol. 2025 Nov 1; 49 (11):1105-1113 Epub 2025 July 09
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  27. Papanicolau-Sengos A, Singh O, Park K, Snuderl M, Tretiakova M, Merino M, Stohr B, Simko J, Deng FM, Chan E, Wu J, Barreto J, Gupta R, Park B, Turakulov R, Abdullaev Z, Solomon DA, Aldape K. DNA Methylation-Based Classification of Kidney Neoplasms. Mod Pathol. 2025 Nov; 38 (11):100884 Epub 2025 Sept 10
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  28. Pai EL, Matsumoto Y, Dou D, Nelluri S, Devi P, Priori S, Amankulor N, Alonso-Basanta M, Singh O, Abdullaev Z, Aldape K, Desai A, Mohan S, Nasrallah MP. Molecularly defined oligodendroglioma evolving to osseous metastases. J Neuropathol Exp Neurol. 2025 Oct 1; 84 (10):954-959
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  29. Landry AP, Wang JZ, Yefet LS, Liu J, Patil V, Zhang WJ, Sosa J, Ellenbogen Y, Gui C, Ajisebutu A, Aldape K, Gao A, Kislinger T, Chen EX, Nassiri F, Zadeh G. Metabolic profiling of meningioma reveals novel subgroup-specific biologic insights and outcome dependencies. Neuro Oncol. 2025 Sep 17; 27(8):2047-2059.
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  30. Gong L, Luo J, Yang E, Ru B, Qi Z, Yang Y, Rani A, Purohit A, Zhang Y, Guan G, Paul R, Vu T, Chen Z, Ji R, Day CP, Wu C, Merlino G, Fitzgerald D, Altan-Bonnet G, Aldape K, Wu J, Guan X, Jiang P. Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy. Cell. 2025 Sep 4; 188 (18):5062-5080.e32 Epub 2025 July 28
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  31. Gui C, Wang JZ, Patil V, Landry AP, Singh O, Castelo-Branco P, Tabori U, Aldape K, Behling F, Barnholtz-Sloan JS, Horbinski C, Tabatabai G, Ajisebutu A, Liu J, Patel Z, Yakubov R, Kaloti R, Ellenbogen Y, Wilson C, Cohen-Gadol A, Tatagiba M, Holland EC, Sloan AE, Chotai S, Chambless LB, Gao A, Makarenko S, Yip S, Nassiri F, Zadeh G, International Consortium on Meningiomas (ICOM). Analysis of TERT association with clinical outcome in meningiomas: a multi-institutional cohort study. Lancet Oncol. 2025 Sep; 26 (9):1191-1203
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  32. Nassiri F, Patil V, Yefet LS, Singh O, Liu J, Dang RMA, Yamaguchi TN, Daras M, Cloughesy TF, Colman H, Kumthekar PU, Chen CC, Aiken R, Groves MD, Ong SS, Ramakrishna R, Vogelbaum MA, Khagi S, Kaley T, Melear JM, Peereboom DM, Rodriguez A, Yankelevich M, Nair SG, Puduvalli VK, Aldape K, Gao A, Lopez-Janeiro A, de Andrea CE, Alonso MM, Boutros P, Robbins J, Mason WP, Sonabend AM, Stupp R, Fueyo J, Gomez-Manzano C, Lang FF, Zadeh G. Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial. Nat Med. 2025 Sep; 31 (9):3204
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  33. Groisser A, John L, Kirkorian AY, Gulino SP, Rossi CT, Vyas PK, Gagan J, Raffeld M, Aldape K, Barr FG, Xi L, Lee I, Ferrone CK, Pack SD, Kaplan RN, Goldstein AM, Barnhill R, Yohe M, Sargen MR. Immunotherapy Resistance in Lethal Prepubescent Spitz Melanoma With TERT Promoter Variant. JCO Precis Oncol. 2025 Sep; 9:e2500407 Epub 2025 Sept 02
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  34. Fleming JL, Pugh SL, Chang SM, McElroy JP, Becker AP, Aldape KD, Shih HA, Ashby LS, Hunter GK, Bahary JP, Schultz CJ, Kavanagh BD, Puduvalli VK, Robins HI, Werner-Wasik M, Mehta M, Chakravarti A. Comprehensive Molecular Analysis in NRG Oncology/RTOG 9813: A Phase 3 Study of Radiation and Temozolomide Versus Radiation and BCNU/CCNU in Anaplastic Astrocytoma. Int J Radiat Oncol Biol Phys. 2025 Sep 1; 123 (1):84-92 Epub 2025 Mar 29
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  35. Zane LK, Yee LM, Chang TC, Sklar J, Yang G, Wen JD, Li P, Harrington R, Sims DJ, Harper K, Trent JM, LoBello JR, Szelinger S, Benson K, Zeng J, Poorman K, Xu D, Frampton GM, Pavlick DC, Miller VA, Tandon B, Swat W, Weiss L, Funari VA, Conroy JM, Prescott JL, Chandra PK, Ma C, Champion KJ, Baschkopf GX, Fesko YA, Freitas TAK, Tomlins SA, Hovelson DH, White K, Sorrells S, Tell R, Beaubier N, King D, Li L, Kelly K, Uvalic J, Meyers B, Kolhe R, Lindeman NI, Baltay M, Sholl LM, Lopategui J, Vail E, Zhang W, Telatar M, Afkhami M, Hsiao SJ, Mansukhani MM, Adams E, Jiang L, Aldape KD, Raffeld M, Xi L, Stehr H, Segal JP, Aisner DL, Davies KD, Brown NA, Livingston RJ, Konnick EQ, Song W, Solomon JP, Walther Z, McShane LM, Harris LN, Chen AP, Tsongalis GJ, Hamilton SR, Flaherty KT, O'Dwyer PJ, Conley BA, Patton DR, Iafrate AJ, Williams PM, Tricoli JV, Karlovich C, NCI-MATCH Designated Laboratories//for NCI-COMPASS Team//for NCI-MATCH Designated Laboratories. A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial. Clin Cancer Res. 2025 Aug 14; 31 (16):3512-3525
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  36. Cook DJ, Trejo-Lopez JA, Pitel BA, Saha N, Koganti T, Hardcastle J, Smoley S, Isaacson M, Gandham M, Sivasankaran G, Dasari S, Fung KM, Powell SZ, Trivedi D, Abdullaev Z, Aldape K, Quezado M, Pratt D, Cimino PJ, Edgar MA, Vaubel RA, Raghunathan A, Giannini C, Jenkins RB, Ida CM. Expanding the spectrum of TERT promoter mutations in CNS tumors: A case series of non-canonical mutations. J Neuropathol Exp Neurol. 2025 Aug 1; 84 (8):746-748
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  37. Shatara M, Brossier NM, Cluster A, Mian AY, Dahiya S, Armstrong AE, Hirbe AC, Gutmann DH, Aldape K, Abdelbaki MS. Collaborative frontiers in pediatric neuro-oncology: establishing an international tumor board for enhanced care and global impact. Int J Clin Oncol. 2025 Aug; 30 (8):1659-1669 Epub 2025 May 30
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  38. Sargen MR, Fitzhugh MH, Ko JS, Close AG, Horton SC, Malik F, Furtado LV, Bahrami A, Seynnaeve BKN, Pappo AS, Liu V, Cheung K, Pack SD, Xi L, Raffeld M, Lee I, Gagan J, Aldape K, Barr FG, Hewitt SM, Ferrone CK, Hayden A, Hatton JN, Goldstein AM, Pfeiffer RM, Widemann B, Malone MFW, Gross AM, Kaplan R, Yohe ME, Berrebi KG. Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series. Pediatr Blood Cancer. 2025 Aug; 72 (8):e31814 Epub 2025 May 19
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  39. Nagarkar A, Turbeville J, Hinshaw MA, LeBoit PE, Gagan J, Raffeld M, Aldape K, Shah N, Barr FG, Xi L, Lee I, Ferrone CK, Pack SD, Kaplan R, Malone MFW, Yohe M, Sargen MR. Large Congenital Melanocytic Nevus With LMNA::NTRK1 Fusion: Expanding Targeted Therapy Options for Congenital Nevi and Melanoma. J Cutan Pathol. 2025 Aug; 52 (8):523-527 Epub 2025 June 03
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  40. Lou J, Yong W, Aldape K, Chu E, Hui C, Hsu FPK, Zheng M, Ribeiro A, Fote G, Na D, Yuen CA. CNS Tumor with BCOR/BCORL1 Fusion: A Rare Tumor Entity. Int J Mol Sci. 2025 Jul 14; 26 (14) Epub 2025 July 14
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  41. Zhu Y, Carabenciov DD, Johnson DR, Trejo-Lopez JA, Nguyen AT, Raghunathan A, Lanzino G, Ida CM, Zepeda-Mendoza CJ, Dasari S, Russler-Germain E, Dahiya S, Quezado M, Aldape K, Giannini C. Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH-wildtype. Brain Pathol. 2025 Jul; 35 (4):e13326 Epub 2024 Dec 18
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  42. Landry AP, Wang JZ, Liu J, Patil V, Gui C, Patel Z, Ajisebutu A, Ellenbogen Y, Wei Q, Singh O, Sosa J, Mansouri S, Wilson C, Cohen-Gadol AA, Zaazoue MA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chotai S, Chambless LB, Rebchuk AD, Makarenko S, Yip S, Mansouri A, Tsang DS, Aldape K, Gao A, International Consortium on Meningiomas (ICOM), Nassiri F, Zadeh G. Development and validation of a molecular classifier of meningiomas. Neuro Oncol. 2025 Jun 21; 27(5):1258-1269.
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  43. Landry AP, Wang JZ, Patil V, Liu J, Gui C, Ellenbogen Y, Ajisebutu A, Yefet L, Wei Q, Singh O, Sosa J, Mansouri S, Cohen-Gadol AA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chotai S, Chambless LB, Mansouri A, Makarenko S, Yip S, Ehret F, Capper D, Tsang DS, Moliterno J, Gunel M, Wesseling P, Sahm F, Aldape K, Gao A, Zadeh G, Nassiri F. Chromosome 1p Loss and 1q Gain for Grading of Meningioma. JAMA Oncol. 2025 Jun 1; 11 (6):644-649
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  44. Margossian KO, Marciniak M, Al-Warqi A, Aldape K, Kocak M, Munoz L, Michaelides E, Marshall MS. An adult patient with initial presentation of myxopapillary ependymoma at the cerebellopontine angle: illustrative case. J Neurosurg Case Lessons. 2025 May 26; 9 (21)
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  45. Landry AP, Wang JZ, Patil V, Gui C, Mamatjan Y, Patel Z, Yakubov R, Kaloti R, Habibi P, Wilson M, Ajisebutu A, Ellenbogen Y, Wei Q, Singh O, Sosa J, Mansouri S, Wilson C, Cohen-Gadol AA, Virtanen P, Burket N, Blackwell M, Koenig J, Alfonso A, Davis J, Zaazoue MA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chotai S, Chambless LB, Mansouri A, Ehret F, Capper D, Tsang DS, Aldape K, Gao A, International Consortium on Meningiomas (ICOM), Nassiri F, Zadeh G. Validation and next-generation update of a DNA methylation-based recurrence predictor for meningioma: A multicenter prospective study. Neuro Oncol. 2025 May 15; 27(4):1004-1016.
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  46. Schmid S, Mirchia K, Tietze A, Liu I, Siewert C, Nuckles J, Schittenhelm J, Behling F, Snuderl M, Hartmann C, Brandner S, Paine SML, Korshunov A, Hasselblatt M, Coras R, Epari S, Stadelmann C, Zechel S, Simon M, Wilson Y, Gianno F, Lucas CG Jr, Zherebitskiy V, Kaimaktchiev VB, Robinson L, Aldape K, Hoving EW, Tops BBJ, Perera AA, Goller P, Hernaiz Driever P, Wesseling P, Koch A, Perry A, Sahm F, Jones DTW, Capper D. VGLL fusions define a new class of intraparenchymal central nervous system schwannoma. Neuro Oncol. 2025 May 15; 27 (4):1031-1045
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  47. Singh O, Dampier C, Abdullaev Z, Dazelle K, Chung HJ, Conway K, Camelo-Piragua S, Neill S, Brown D, Nix JS, Giannini C, Macaulay R, Marker D, Skaugen J, Kulich S, Lee H, Aboud O, Pytel P, Borys E, Perry A, Naqib-Osman L, Fernandes IL, Mao Q, Alashari M, Thomas C, Helgager J, Gubbiotti MA, Newman J, Tiwari N, Cimino PJ, Quezado M, Aldape KD, Nasrallah MP. Diffuse astrocytoma, AYA-type, frequently MAPK-altered: report of 45 patients. Acta Neuropathol. 2025 Apr 9; 149 (1):32 Epub 2025 Apr 09
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  48. El-Dana F, Aldape K, Abdullaev Z, Sheth SA, Mandel J, Lu HC. Low-grade glial/glioneuronal tumor with YAP1::FAM118B fusion: A novel molecular finding. J Neuropathol Exp Neurol. 2025 Apr 1; 84 (4):360-362
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  49. Horbinski C, Solomon DA, Lukas RV, Packer RJ, Brastianos P, Wen PY, Snuderl M, Berger MS, Chang S, Fouladi M, Phillips JJ, Nabors B, Brat DJ, Huse JT, Aldape K, Sarkaria JN, Holdhoff M, Burns TC, Peters KB, Mellinghoff IK, Arons D, Galanis E. Molecular Testing for the World Health Organization Classification of Central Nervous System Tumors: A Review. JAMA Oncol. 2025 Mar 1; 11 (3):317-328
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  50. Sahm F, Aldape KD, Brastianos PK, Brat DJ, Dahiya S, von Deimling A, Giannini C, Gilbert MR, Louis DN, Raleigh DR, Reifenberger G, Santagata S, Sarkar C, Zadeh G, Wesseling P, Perry A. cIMPACT-NOW update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas. Neuro Oncol. 2025 Feb 10; 27 (2):319-330
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  51. Reimann RR, Gramatzki D, Bink A, Hench J, Frank S, Haberecker M, Hortobagyi T, Egervari K, Merkler D, Aldape K, Weller M. Long survival in a patient with fumarate hydratase mutation-associated glioma. J Neuropathol Exp Neurol. 2025 Feb 1; 84 (2):164-167
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  52. Morales-Vargas B, Saad H, Refai D, Schniederjan M, Abdullaev Z, Aldape K, Abedalthagafi M. A case of myxopapillary ependymoma with predominant giant cell morphology: A rare entity with comprehensive genomic profiling and review of literature. Neuropathology. 2025 Feb; 45 (1):13-19 Epub 2024 Apr 19
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  447. Hassaneen W, Levine NB, Suki D, Salaskar AL, de Moura Lima A, McCutcheon IE, Prabhu SS, Lang FF, DeMonte F, Rao G, Weinberg JS, Wildrick DM, Aldape KD, Sawaya R. Multiple craniotomies in the management of multifocal and multicentric glioblastoma. Clinical article. J Neurosurg. 2011 Mar; 114 (3):576-84 Epub 2010 Aug 06
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  448. Sampson JH, Aldape KD, Archer GE, Coan A, Desjardins A, Friedman AH, Friedman HS, Gilbert MR, Herndon JE, McLendon RE, Mitchell DA, Reardon DA, Sawaya R, Schmittling R, Shi W, Vredenburgh JJ, Bigner DD, Heimberger AB. Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma. Neuro Oncol. 2011 Mar; 13 (3):324-33 Epub 2010 Dec 10
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  451. Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG 2nd, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Hook M, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W. Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest. 2011 Jan; 121 (1):161-73 Epub 2010 Dec 22
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  454. Liu Y, Shete S, Wang LE, El-Zein R, Etzel CJ, Liang FW, Armstrong G, Tsavachidis S, Gilbert MR, Aldape KD, Xing J, Wu X, Wei Q, Bondy ML. Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk. Carcinogenesis. 2010 Oct; 31 (10):1762-9 Epub 2010 July 07
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  456. Lin Q, Balasubramanian K, Fan D, Kim SJ, Guo L, Wang H, Bar-Eli M, Aldape KD, Fidler IJ. Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels. Neoplasia. 2010 Sep; 12 (9):748-54
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  462. McGovern SL, Aldape KD, Munsell MF, Mahajan A, DeMonte F, Woo SY. A comparison of World Health Organization tumor grades at recurrence in patients with non-skull base and skull base meningiomas. J Neurosurg. 2010 May; 112 (5):925-33
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  464. Dai B, Pieper RO, Li D, Wei P, Liu M, Woo SY, Aldape KD, Sawaya R, Xie K, Huang S. FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes. Cancer Res. 2010 Apr 1; 70 (7):2951-61 Epub 2010 Mar 23
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  465. Rivera AL, Pelloski CE, Gilbert MR, Colman H, De La Cruz C, Sulman EP, Bekele BN, Aldape KD. MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol. 2010 Feb; 12 (2):116-21 Epub 2009 Dec 14
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  466. Costa BM, Smith JS, Chen Y, Chen J, Phillips HS, Aldape KD, Zardo G, Nigro J, James CD, Fridlyand J, Reis RM, Costello JF. Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma. Cancer Res. 2010 Jan 15; 70 (2):453-62 Epub 2010 Jan 12
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  544. Bohinski RJ, Mendel E, Aldape KD, Rhines LD. Intramedullary and extramedullary solitary fibrous tumor of the cervical spine. Case report and review of the literature. J Neurosurg. 2004 Apr; 100 (4 Suppl Spine):358-63
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  546. Pandita A, Aldape KD, Zadeh G, Guha A, James CD. Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR. Genes Chromosomes Cancer. 2004 Jan; 39 (1):29-36
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  547. Trebst C, Staugaitis SM, Tucky B, Wei T, Suzuki K, Aldape KD, Pardo CA, Troncoso J, Lassmann H, Ransohoff RM. Chemokine receptors on infiltrating leucocytes in inflammatory pathologies of the central nervous system (CNS). Neuropathol Appl Neurobiol. 2003 Dec; 29 (6):584-95
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  549. Zhang L, Miles MF, Aldape KD. A model of molecular interactions on short oligonucleotide microarrays. Nat Biotechnol. 2003 Jul; 21 (7):818-21 Epub 2003 June 08
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  550. Lee HK, Chang EL, Fuller GN, Aldape KD, Atkinson GJ, Levy LB, McCutcheon IE, Maor MH. The prognostic value of neurologic function in astrocytic spinal cord glioma. Neuro Oncol. 2003 Jul; 5 (3):208-13
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  551. Lang FF, Bruner JM, Fuller GN, Aldape K, Prados MD, Chang S, Berger MS, McDermott MW, Kunwar SM, Junck LR, Chandler W, Zwiebel JA, Kaplan RS, Yung WK. Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results. J Clin Oncol. 2003 Jul 1; 21 (13):2508-18
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  555. Rubenstein JL, Combs D, Rosenberg J, Levy A, McDermott M, Damon L, Ignoffo R, Aldape K, Shen A, Lee D, Grillo-Lopez A, Shuman MA. Rituximab therapy for CNS lymphomas: targeting the leptomeningeal compartment. Blood. 2003 Jan 15; 101 (2):466-8 Epub 2002 Sept 05
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  556. Burton EC, Lamborn KR, Feuerstein BG, Prados M, Scott J, Forsyth P, Passe S, Jenkins RB, Aldape KD. Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma. Cancer Res. 2002 Nov 1; 62 (21):6205-10
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  560. Barker FG 2nd, Simmons ML, Chang SM, Prados MD, Larson DA, Sneed PK, Wara WM, Berger MS, Chen P, Israel MA, Aldape KD. EGFR overexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2001 Oct 1; 51 (2):410-8
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  562. Sonoda Y, Ozawa T, Hirose Y, Aldape KD, McMahon M, Berger MS, Pieper RO. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma. Cancer Res. 2001 Jul 1; 61 (13):4956-60
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  563. Cooper EC, Aldape KD, Abosch A, Barbaro NM, Berger MS, Peacock WS, Jan YN, Jan LY. Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy. Proc Natl Acad Sci U S A. 2000 Apr 25; 97 (9):4914-9
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  564. Smyth MD, Pitts L, Jackler RK, Aldape KD. Metastatic spinal ependymoma presenting as a vestibular schwannoma. Case illustration. J Neurosurg. 2000 Apr; 92 (2 Suppl):247
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