Grand Rounds: Individualizing Diagnosis and Therapy for IBS

April 11, 2014


Arthur Beyder, M.D., Ph.D., and Gianrico Farrugia, M.D., discuss the morbidity, pathophysiology and genetics of irritable bowel syndrome (IBS), a complex genetic disease. In some cases, IBS is an ion channelopathy. Drs. Beyder and Farrugia discuss the involvement of SCN5A and NaV1.5 mutations in patients with IBS.