Drug information provided by: Merative, Micromedex®
Selpercatinib is used to treat locally advanced or metastatic (cancer that has already spread) non-small cell lung cancer (NSCLC) in patients whose tumors have RET fusion-positive genes. Your doctor will perform a test to check for the RET gene fusion before you use this medicine.
Selpercatinib is also used to treat advanced or metastatic (cancer that has already spread) medullary thyroid cancer (MTC) in patients whose tumors have abnormal RET (RET-mutant) genes. Your doctor will perform a test to check for the abnormal RET gene before you use this medicine.
Selpercatinib is also used to treat advanced or metastatic (cancer that has already spread) thyroid cancer in patients whose tumors have RET fusion-positive genes. Your doctor will perform a test to check for the RET gene fusion before you use this medicine. It is used in patients who needs a medicine by mouth or injection and have received radioactive iodine but did not work.
Selpercatinib is also used to treat locally advanced or metastatic (cancer that has already spread) solid tumors in patients whose tumors have RET fusion-positive genes. It is used in patients whose tumors have gotten worse on or after receiving other treatments or there are no treatment options that work well.
Selpercatinib belongs to the group of medicines called antineoplastics (cancer medicines). It works by interfering with the growth of cancer cells, which are eventually destroyed.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
Portions of this document last updated: Sept. 01, 2023
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