التجارب السريرية بالأسفل التجارب السريرية الحالية.13 دراسات في طِب الرُّوماتيزم (افتح الدراسات فقط). غربل قائمة الدراسات هذه بالموقع والحالة وغيرها. Exploring the Role of B-cell Activating Factor Receptor (BAFFR)-based Chimeric Antigen Receptor T-cell (CAR T) in BAFFR-expressing B-cell Hematologic Malignancies and Autoimmune Rheumatologic Disorders Jacksonville, Fla. The purposes of this study are to explore the therapeutic efficacy of BAFFR-CAR T cells in BAFFR-expressing B-cell hematologic malignancies including large B-cell, mantle cell and follicular lymphoma, chronic lymphocytic leukemia (CLL) and B-cell acute lymphoblastic leukemia (B-cell ALL) using primary tumor and/or patient derived xenograft models, and to explore the therapeutic efficacy of BAFFR-CAR T cells in autoimmune rheumatologic diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis using primary samples and/or patient derived xenograft models. A Study to Enroll Patients of Rheumatic Diseases and First-degree Relatives in a Biobank Rochester, Minn. The purpose of this study is to enroll rheumatic disease patients and first-degree relatives in a biobank, and to follow them over time to assess health outcomes and collect additional specimens. Daratumumab to Treat Active Lupus Nephritis Rochester, Minn. The purpose of this study is to assess the effectiveness and safety of daratumumab in inducing complete or partial remission in patients with active class III or IV (± V) lupus nephritis (LN) as measured by change in proteinuria and serum creatinine. The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach Rochester, Minn. This study is a multi-center randomized controlled trial to evaluate the effects of using low-dose prednisone as compared to stopping prednisone treatment entirely. Participants will be randomized 1:1 to taper their prednisone dose down to 5 mg/day or to 0 mg/day for the duration of the study (approximately six months) or until a study endpoint. The ANSWERS Study Rochester, Minn. The purpose of this study is to better understand Antiphospholipid syndrome (APS) pathophysiology and to aid development of targeted therapeutics. A Study to Evaluate Cardiopulmonary Complications in Systemic Sclerosis Rochester, Minn. The purpose of this study is to assess whether our not the percentage of pulmonary related vascular structures (PRVS) determined by the quantitative CT (Q-CT) tool CALIPER is a novel measure that can be used for the early detection of pulmonary vascular remodeling in patients with SSc. pulmonary related vascular structures PRA023 in Subjects with Systemic Sclerosis Associated with Interstitial Lung Disease Scottsdale/Phoenix, Ariz. The purpose of this study is to assess the safety, tolerability, and effectiveness of PRA023 in subjects with Systemic Sclerosis (SSc) with diffuse cutaneous disease and Interstitial Lung Disease (ILD). MEPOLIZUMAB FOR THE TREATMENT OF EOSINOPHILIC FASCIITIS: AN OPEN-LABEL, SINGLE-ARM, EXPLORATORY STUDY Jacksonville, Fla. The purpose of this study is to investigate the efficacy of mepolizumab in the treatment of eosinophilic fasciitis. Biomarkers in Autoimmune and Inflammatory Diseases Rochester, Minn. The purpose of this study is to identify biomarkers in people with autoimmune or inflammatory disease and in healthy people. We will use these biomarkers to develop tests that will help us better understand the same biomarkers in the blood of people who have autoimmune and inflammatory diseases. A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients Scottsdale/Phoenix, Ariz. The purpose of this study is to evaluate the safety and tolerability of ixazomib in patients with scleroderma. التصفّح دراسات سريرية توجّه للصفحة 11 توجّه للصفحة 22 التاليالصفحة التالية بالأسفل التجارب السريرية الحالية.13 دراسات في طِب الرُّوماتيزم (افتح الدراسات فقط). غربل قائمة الدراسات هذه بالموقع والحالة وغيرها. Exploring the Role of B-cell Activating Factor Receptor (BAFFR)-based Chimeric Antigen Receptor T-cell (CAR T) in BAFFR-expressing B-cell Hematologic Malignancies and Autoimmune Rheumatologic Disorders Jacksonville, Fla. The purposes of this study are to explore the therapeutic efficacy of BAFFR-CAR T cells in BAFFR-expressing B-cell hematologic malignancies including large B-cell, mantle cell and follicular lymphoma, chronic lymphocytic leukemia (CLL) and B-cell acute lymphoblastic leukemia (B-cell ALL) using primary tumor and/or patient derived xenograft models, and to explore the therapeutic efficacy of BAFFR-CAR T cells in autoimmune rheumatologic diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis using primary samples and/or patient derived xenograft models. A Study to Enroll Patients of Rheumatic Diseases and First-degree Relatives in a Biobank Rochester, Minn. The purpose of this study is to enroll rheumatic disease patients and first-degree relatives in a biobank, and to follow them over time to assess health outcomes and collect additional specimens. Daratumumab to Treat Active Lupus Nephritis Rochester, Minn. The purpose of this study is to assess the effectiveness and safety of daratumumab in inducing complete or partial remission in patients with active class III or IV (± V) lupus nephritis (LN) as measured by change in proteinuria and serum creatinine. The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach Rochester, Minn. This study is a multi-center randomized controlled trial to evaluate the effects of using low-dose prednisone as compared to stopping prednisone treatment entirely. Participants will be randomized 1:1 to taper their prednisone dose down to 5 mg/day or to 0 mg/day for the duration of the study (approximately six months) or until a study endpoint. The ANSWERS Study Rochester, Minn. The purpose of this study is to better understand Antiphospholipid syndrome (APS) pathophysiology and to aid development of targeted therapeutics. A Study to Evaluate Cardiopulmonary Complications in Systemic Sclerosis Rochester, Minn. The purpose of this study is to assess whether our not the percentage of pulmonary related vascular structures (PRVS) determined by the quantitative CT (Q-CT) tool CALIPER is a novel measure that can be used for the early detection of pulmonary vascular remodeling in patients with SSc. pulmonary related vascular structures PRA023 in Subjects with Systemic Sclerosis Associated with Interstitial Lung Disease Scottsdale/Phoenix, Ariz. The purpose of this study is to assess the safety, tolerability, and effectiveness of PRA023 in subjects with Systemic Sclerosis (SSc) with diffuse cutaneous disease and Interstitial Lung Disease (ILD). MEPOLIZUMAB FOR THE TREATMENT OF EOSINOPHILIC FASCIITIS: AN OPEN-LABEL, SINGLE-ARM, EXPLORATORY STUDY Jacksonville, Fla. The purpose of this study is to investigate the efficacy of mepolizumab in the treatment of eosinophilic fasciitis. Biomarkers in Autoimmune and Inflammatory Diseases Rochester, Minn. The purpose of this study is to identify biomarkers in people with autoimmune or inflammatory disease and in healthy people. We will use these biomarkers to develop tests that will help us better understand the same biomarkers in the blood of people who have autoimmune and inflammatory diseases. A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients Scottsdale/Phoenix, Ariz. The purpose of this study is to evaluate the safety and tolerability of ixazomib in patients with scleroderma. التصفّح دراسات سريرية توجّه للصفحة 11 توجّه للصفحة 22 التاليالصفحة التالية طلب تحديد موعد المواقع والسفر والإقامةالأبحاث 01/04/2020 تبادلها عبر ارسلها على الفيس بوكارسلها في تغريدة طِب الرُّوماتيزمالأجزاءنظرة عامةالاختبارات والتشخيصالحلات التي يتم علاجهاالأطباءمجموعات التخصصالخبرة و مراتب التصنيفالمواقع والسفر والإقامةالتجارب السريريةالأبحاثقصص المرضىالتكاليف والتأمين الصحيالأخبار من Mayo Clinicإحالة المرضى الأبحاث: الأمر برمته يتوقف على المرضى الأجزاءطلب موعدنظرة عامةالاختبارات والتشخيصالحلات التي يتم علاجهاالأطباءمجموعات التخصصالخبرة و مراتب التصنيفالمواقع والسفر والإقامةالتجارب السريريةالأبحاثقصص المرضىالتكاليف والتأمين الصحيالأخبار من Mayo Clinicإحالة المرضى ORG-20476802 الأقسام والمراكز المراكز والأقسام الطبية طِب الرُّوماتيزم