Osarenoma U. Olomu, M.D.

Dr. Osarenoma Olomu is a fellowship‑trained otolaryngologist (ENT) at Mayo Clinic in Jacksonville, Florida, specializing in chronic sinusitis, nasal polyps, loss of smell (anosmia), allergic fungal sinusitis, and complex sinonasal and skull base disorders.

As an assistant professor of otolaryngology at the Mayo Clinic College of Medicine and Science, he is deeply committed to advancing patient care, medical education, and innovative research. Dr. Olomu combines advanced surgical expertise with a compassionate, patient‑centered approach, helping individuals breathe more comfortably, regain their sense of smell, and improve their overall quality of life.

He serves as Vice Chair for Education and Residency Program Director in the Department of Otolaryngology: Head & Neck Surgery, where he leads training programs that shape the next generation of ENT specialists. His clinical practice integrates cutting‑edge endoscopic techniques, evidence‑based medical therapies, and a personalized approach to managing both routine and highly complex sinonasal conditions.

His clinical expertise includes:

• Chronic rhinosinusitis (with and without nasal polyps)
• Allergic fungal sinusitis
• Anosmia and olfactory disorders
• Endoscopic sinus surgery
• Endoscopic skull base surgery
• CSF leak evaluation and management
• Office‑based rhinologic procedures

Dr. Olomu has earned numerous awards and honors in recognition of his excellence in patient care, scholarship, and research, including the Unparalleled Experience Award from Mayo Clinic in Florida (2023 and 2024), placing him in the top 1% nationally for patient experience based on survey data.

Additional distinctions include the Monsanto Distinguished Scholar Award, National Merit Scholar recognition from the National Merit Scholarship Program, the Outstanding Research Award from the National Cancer Institute, and the Michael Paparella Research Award from Washington University School of Medicine.

Dr. Olomu's research is focused on improving outcomes for patients with chronic sinus disease. His areas of investigation include allergic fungal sinusitis and the role of geographic and environmental factors, the long-term risk of dementia in patients with anosmia, the use of 3D-printed skull models for surgical simulation and training, vestibular psychophysics and aging, and the relationship between olfactory dysfunction and neurodegenerative disease.

He serves as a peer reviewer for leading journals such as the International Forum of Allergy & Rhinology and the Journal of Neurological Surgery Part B: Skull Base. Dr. Olomu is also an active member of several professional organizations, including the American Academy of Otolaryngology — Head and Neck Surgery, the American Rhinologic Society, the Society of University Otolaryngologists, and the North American Skull Base Society.

Outside of medicine, Dr. Olomu enjoys spending time with his wife and children. He is certified in wilderness first aid and volunteers with his local Boy Scouts organization, reflecting his strong commitment to mentorship, service and community involvement.