There are many possible causes of unexplained weight loss, including undiagnosed celiac disease and thyroid disorders. Potential causes of unexplained weight loss include:

  1. Addison's disease
  2. Cancer
  3. Celiac disease
  4. COPD — Chronic obstructive pulmonary disease
  5. Crohn's disease
  6. Dementia
  7. Depression
  8. Diabetes
  9. Heart failure
  10. HIV/AIDS
  11. Hypercalcemia
  12. Hyperthyroidism (overactive thyroid)
  13. Hypothyroidism (a thyroid disorder)
  14. Parkinson's disease
  15. Peptic ulcer
  16. Tuberculosis
  17. Ulcerative colitis

Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.

Aug. 20, 2011