Signs and symptoms are likely to develop gradually — often appearing one to three weeks after exposure to the disease.
Once signs and symptoms do appear, you're likely to experience:
- Fever that starts low and increases daily, possibly reaching as high as 104.9 F (40.5 C)
- Weakness and fatigue
- Muscle aches
- Dry cough
- Loss of appetite and weight loss
- Abdominal pain
- Diarrhea or constipation
- Extremely swollen abdomen
If you don't receive treatment, you may:
- Become delirious
- Lie motionless and exhausted with your eyes half-closed in what's known as the typhoid state
In addition, life-threatening complications often develop at this time.
In some people, signs and symptoms may return up to two weeks after the fever has subsided.
When to see a doctor
See a doctor immediately if you suspect you have typhoid fever. If you become ill while traveling in a foreign country, call the U.S. Consulate for a list of doctors. Better yet, find out in advance about medical care in the areas you'll visit, and carry a list of the names, addresses and phone numbers of recommended doctors.
If you develop signs and symptoms after you return home, consider consulting a doctor who focuses on international travel medicine or infectious diseases. A specialist may be able to recognize and treat your illness more quickly than can a doctor who isn't familiar with these areas.
July 11, 2015
- Wain J, et al. Typhoid fever. The Lancet. 2015;385:1136.
- Longo DL, et al., eds. Salmonellosis In: Harrison's Principles of Internal Medicine. 19th ed. New York, N.Y.: The McGraw-Hill Companies; 2015. http://www.accessmedicine.com. Accessed June 10, 2015.
- Typhoid fever. Centers for Disease Control and Prevention. http://www.cdc.gov/nczved/divisions/dfbmd/diseases/typhoid_fever. Accessed June 10, 2015.
- Hohmann EL. Epidemiology, microbiology, clinical manifestations, and diagnosis of typhoid fever. http://www.uptodate.com/home. Accessed June 10, 2015.
- Hohmann EL. Treatment and prevention of typhoid fever. http://www.uptodate.com/home. Accessed June 10, 2015.
- Anwar E, et al. Vaccines for preventing typhoid fever. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001261.pub3/abstract. Accessed June 10, 2015.