Triple X syndrome may not cause any signs or symptoms. If symptoms do appear, they may include:
- Tall stature
- Vertical skinfolds that may cover the inner corners of the eyes (epicanthal folds)
- Delayed development of speech and language skills
- Weak muscle tone (hypotonia)
- Curved pinky fingers (clinodactyly)
- Behavior and mental health problems
- Premature ovarian failure or ovary abnormalities
- Constipation or abdominal pains
When to see a doctor
See your daughter's doctor if you have any concerns about your daughter's developmental progress. Your doctor can help determine what may be the cause and suggest appropriate action.
Nov. 08, 2012
- Triple X syndrome. U.S. National Library of Medicine's Genetics Home Reference. http://ghr.nlm.nih.gov/condition/triple-x-syndrome. Accessed Sept. 9, 2012.
- 47 XXX syndrome. Genetics and Rare Diseases Information Center. http://rarediseases.info.nih.gov/GARD/Condition/5672/47_XXX_syndrome.aspx. Accessed Sept. 9, 2012.
- Afshun A. Triple X syndrome. Journal of the Pakistan Medical Association. 2012;62:392.
- Otter M, et al. Triple X syndrome: A review of the literature. European Journal of Human Genetics. 2010;18:265.
- Chromosome abnormalities. National Human Genome Research Institute. http://www.genome.gov/11508982#6. Accessed Sept. 10, 2012.
- Chromosomal abnormalities. March of Dimes. http://www.marchofdimes.com/baby/birthdefects_chromosomal.html. Accessed Sept. 11, 2012.
- Tartaglia NR, et al. A review of trisomy X (47,XXX). Orphanet Journal of Rare Diseases. 2010;5:8.
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