Several complications can occur immediately or soon after a traumatic brain injury. Severe injuries increase the risk of a greater number of complications and more-severe complications.
Moderate to severe traumatic brain injury can result in prolonged or permanent changes in a person's state of consciousness, awareness or responsiveness. Different states of consciousness include:
- Coma. A person in a coma is unconscious, unaware of anything and unable to respond to any stimulus. This results from widespread damage to all parts of the brain. After a few days to a few weeks, a person may emerge from a coma or enter a vegetative state.
Vegetative state. Widespread damage to the brain can result in a vegetative state. Although the person is unaware of his or her surroundings, he or she may open his or her eyes, make sounds, respond to reflexes, or move.
It's possible that a vegetative state can become permanent, but often individuals progress to a minimally conscious state.
- Minimally conscious state. A minimally conscious state is a condition of severely altered consciousness but with some evidence of self-awareness or awareness of one's environment. It is often a transitional state from a coma or vegetative condition to greater recovery.
Locked-in syndrome. A person in a locked-in state is aware of his or her surroundings and awake, but he or she isn't able to speak or move. The person may be able to communicate with eye movement or blinking.
This state results from damage limited to the lower brain and brainstem. This rarely occurs after trauma and is more commonly due to a stroke in that area of the brain.
- Brain death. When there is no measurable activity in the brain and the brainstem, this is called brain death. In a person who has been declared brain dead, removal of breathing devices will result in cessation of breathing and eventual heart failure. Brain death is considered irreversible.
Some people with traumatic brain injury will have seizures within the first week. Some serious injuries may result in recurring seizures, called post-traumatic epilepsy.
Cerebrospinal fluid may build up in the spaces in the brain (cerebral ventricles) of some people who have had traumatic brain injuries, causing increased pressure and swelling in the brain.
Skull fractures or penetrating wounds can tear the layers of protective tissues (meninges) that surround the brain. This can enable bacteria to enter the brain and cause infections. An infection of the meninges (meningitis) could spread to the rest of the nervous system if not treated.
Blood vessel damage
Several small or large blood vessels in the brain may be damaged in a traumatic brain injury. This damage could lead to a stroke, blood clots or other problems.
Injuries to the base of the skull can damage nerves that emerge directly from the brain (cranial nerves). Cranial nerve damage may result in:
- Paralysis of facial muscles
- Damage to the nerves responsible for eye movements, which can cause double vision
- Damage to the nerves that provide sense of smell
- Loss of vision
- Loss of facial sensation
- Swallowing problems
Many people who have had a significant brain injury will experience changes in their thinking (cognitive) skills. Traumatic brain injury can result in problems with many skills, including:
- Speed of mental processing
- Attention or concentration
Executive functioning problems
- Beginning or completing tasks
Language and communications problems are common following traumatic brain injuries. These problems can cause frustration, conflict and misunderstanding for people with a traumatic brain injury, as well as family members, friends and care providers.
Communication problems may include:
- Difficulty understanding speech or writing
- Difficulty speaking or writing
- Inability to organize thoughts and ideas
- Trouble following conversations
- Trouble with turn taking or topic selection
- Problems with changes in tone, pitch or emphasis to express emotions, attitudes or subtle differences in meaning
- Difficulty deciphering nonverbal signals
- Trouble reading cues from listeners
- Trouble starting or stopping conversations
- Inability to use the muscles needed to form words (dysarthria)
People who've experienced brain injury often experience changes in behaviors. These may include:
- Difficulty with self-control
- Lack of awareness of abilities
- Risky behavior
- Inaccurate self-image
- Difficulty in social situations
- Verbal or physical outbursts
Emotional changes may include:
- Mood swings
- Lack of empathy for others
- Changes in self-esteem
Problems involving senses may include:
- Persistent ringing in the ears
- Difficulty recognizing objects
- Impaired hand-eye coordination
- Blind spots or double vision
- A bitter taste, a bad smell or difficulty smelling
- Skin tingling, pain or itching
- Trouble with balance or dizziness
Degenerative brain diseases
A traumatic brain injury may increase the risk of diseases that result in the gradual degeneration of brain cells and gradual loss of brain functions, though this risk cannot yet be determined with any certainty for an individual. These include:
May. 15, 2014
- Alzheimer's disease, which primarily causes the progressive loss of memory and other thinking skills
- Parkinson's disease, a progressive condition that causes movement problems, such as tremors, rigidity and slow movements
- Dementia pugilistica — most often associated with repetitive blows to the head in career boxing — which causes symptoms of dementia and movement problems
- Traumatic brain injury: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/tbi/detail_tbi.htm. Accessed Feb. 7, 2014.
- Traumatic brain injury (TBI). American Speech-Language-Hearing Association. http://www.asha.org/public/speech/disorders/tbi/. Accessed Feb. 7, 2014.
- Goldman L, et al. Goldman's Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed Feb. 7, 2014.
- Traumatic brain injury. Alzheimer's Association. http://www.alz.org/dementia/traumatic-brain-injury-head-trauma-symptoms.asp. Accessed Feb. 7, 2014.
- Evans RW. Concussion and mild traumatic brain injury. http://www.uptodate.com/home. Accessed Feb. 7, 2014.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Feb. 7, 2014.
- Hemphill JC. Epidemiology, classification, and pathophysiology. http://www.uptodate.com/home. Accessed Feb. 7, 2014.
- Weinhouse GL. Hypoxic-ischemic brain injury: Evaluation and prognosis. http://www.uptodate.com/home. Accessed Feb. 7, 2014.
- McCrory P, et al. Consensus statement on concussion in sport: The 4th International Conference on Concussion in Sport held in Zurich, November 2012. British Journal of Sports Medicine. 2013;47:250.
- Adams JG. Emergency Medicine. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.clinicalkey.com. Accessed Feb. 7, 2014.
- Hemphill JC. Management of acute severe traumatic brain injury. http://www.uptodate.com/home. Accessed Feb. 7, 2014.
- What can I do to help prevent traumatic brain injury? Centers for Disease Control and Prevention. http://www.cdc.gov/traumaticbraininjury/prevention.html. Accessed Feb. 7, 2014.
- Brown AW (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 26, 2014.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.