Diphtheria (dif-THEER-e-uh) is a serious bacterial infection usually affecting the mucous membranes of your nose and throat. Diphtheria typically causes a sore throat, fever, swollen glands and weakness. But the hallmark sign is a sheet of thick, gray material covering the back of your throat, which can block your airway, causing you to struggle for breath.
Diphtheria is extremely rare in the United States and other developed countries, thanks to widespread vaccination against the disease.
Medications are available to treat diphtheria. However, in advanced stages, diphtheria can damage your heart, kidneys and nervous system. Even with treatment, diphtheria can be deadly — up to 3 percent of people who get diphtheria die of it. The rate is higher for children under 15.
Mar. 27, 2014
- Ferri FF. Ferri's Clinical Advisor 2014: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2014. https://www.clinicalkey.com. Accessed Oct. 5, 2013.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Oct. 5, 2013.
- Barroso LF, et al. Epidemiology, pathophysiology and clinical manifestations of diphtheria. http://www.uptodate.com/home. Accessed Oct. 5, 2013.
- Diphtheria. The Merck Manuals: The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/infectious_diseases/gram-positive_bacilli/diphtheria.html. Accessed Oct. 10, 2013.
- Barroso LF. Diagnosis and treatment of diphtheria. http://www.uptodate.com/home. Accessed Oct. 5, 2013.
- Recommended immunization schedule for persons aged 0 through 18 years — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Oct. 8, 2013.
- Recommended immunization schedule for adults aged 19 years and older — United States, 2013. Centers for Disease Control and Prevention http://www.cdc.gov/vaccines/schedules/hcp/child-adolescent.html. Accessed Oct. 8, 2013.
- Tdap (Tetanus, diphtheria, pertussis) vaccine information statement. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/hcp/vis/vis-statements/tdap.html. Accessed Oct. 8, 2013.