Risk factors for antiphospholipid syndrome include:

  • Having an autoimmune condition, such as systemic lupus erythematosus or Sjogren's syndrome.
  • Having certain infections, such as syphilis, HIV/AIDS, hepatitis C or Lyme disease.
  • Taking certain medications, such as hydralazine for high blood pressure, the heart rhythm-regulating medication quinidine, the anti-seizure medication phenytoin (Dilantin) and the antibiotic amoxicillin.
  • Having a family member with antiphospholipid syndrome.

Risk factors for developing symptoms

It's possible to have the antibodies associated with antiphospholipid syndrome without ever developing signs or symptoms. However, if you have these antibodies, your risk of developing blood clots increases particularly if you:

  • Become pregnant
  • Remain immobile for a period of time (such as when you're on bed rest or sitting during a long airline flight)
  • Have surgery
  • Smoke cigarettes
  • Take oral contraceptives
  • Have high cholesterol and triglycerides levels
Apr. 15, 2014