打印 概述乳腺癌精准医疗是一种能够找到最有可能提供帮助的治疗方案的方法。此方法可能涉及检测 DNA 或癌细胞以探索哪种治疗方案效果最好。 乳腺癌精准医疗还有助于诊断和预防。 乳腺癌精准医疗可用于: 查找可能增加患乳腺癌和其他类型癌症风险的 DNA 变异。 通过检测 DNA 了解身体可能会对某一种药物产生怎样的反应。 通过检测癌细胞内的 DNA,选择最可能对癌细胞起作用的药物。 检查构成癌细胞的其他成分,比如细胞表面的某些蛋白质或标志物。这些成分能够让医护团队知道某种药物是否可能对癌症有效。 精准医疗又称为个性化医疗或个体化医疗。 癌症护理是最早使用精准医疗的医学专业之一。一些在癌症护理中使用精准医疗的方法也常用于医学中心。其他一些方法仅供专门的医学中心使用。很多使用精准医疗的方法仅可用于临床试验。这是癌症研究的积极方面。产品与服务A Book: Beyond Breast Cancer 目的乳腺癌精准医疗用于找到最有可能提供帮助的治疗方案。它还可用于乳腺癌诊断和预防。 来自妙佑医疗国际员工 在 Mayo Clinic 治疗 申请预约 医生与科室 Nov. 26, 2024 打印 显示参考文献 Jorde LB, et al., eds. Genetics and precision medicine. In: Medical Genetics. 6th ed. Elsevier; 2020. htps://www.clinicalkey.com. Accessed Dec. 21, 2023. Cyr AE, et al. Individualizing breast cancer risk assessment in clinical practice. Surgical Oncology Clinics of North America. 2023; doi:10.1016/j.soc.2023.05.013. Khan SA. Breast cancer risk reduction: Current status and emerging trends to increase efficacy and reduce toxicity of preventive medication. Surgical Oncology Clincs of North America. 2023; doi:10.1016/j.soc.2023.05.001. Reizine NM, et al. Modern developments in germline pharmacogenomics for oncology prescribing. CA: A Cancer Journal for Clinicians. 2022; doi:10.3322/caac.21722. Biomarker testing for cancer treatment. National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/types/biomarker-testing-cancer-treatment. Accessed Dec. 22, 2023. Liu T, et al. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nature Communications. 2017; doi:10.1038/ncomms13923. Luo K, et al. A phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination. Genes & Development. 2016; doi:10.1101/gad.289439.116. Ingle JN, et al. Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy. Cancer Research. 2016; doi:10.1158/0008-5472.CAN-16-1371. Goetz MP, et al. CYP2D6 metabolism and patient outcome in the Austrian breast and colorectal cancer study group trial (ABCSG) 8. Clinical Cancer Research. 2013; doi:10.1158/1078-0432.CCR-12-2153. Goetz MP, et al. First-in-human phase I study of the tamoxifen metabolite z-endoxifen in women with endocrine-refractory metastatic breast cancer. Journal of Clinical Oncology. 2017; doi:10.1200/JCO.2017.73.3246. D'Assoro AB, et al. The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells. Oncogene. 2013; doi:10.1038/onc.2012.628. Ingle JN, et al. Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole. Steroids. 2015; doi:10.1016/j.steroids.2014.08.007. Jayaraman S, et al. Endoxifen, an estrogen receptor targeted therapy: From bench to bedside. Endocrinology. 2021; doi:10.1210/endocr/bqab191. Goetz MP, et al. Tumor sequencing and patient-derived xenografts in the neoadjuvant treatment of breast cancer. Journal of the National Cancer Institute. 2017; doi:10.1093/jnci/djw306. Hu C, et al. Classification of BRCA2 variants of uncertain significance (VUS) using an ACMG/AMP model incorporating a homology-directed repair (HDR) functional assay. Clinical Cancer Research. 2022; doi:10.1158/1078-0432.CCR-22-0203. Couch FJ, et al. Associations between cancer predisposition testing panel genes and breast cancer. JAMA Oncology. 2017; doi:10.1001/jamaoncol.2017.0424. Precision medicine initiative cohort program biobank. NIH RePORTER. https://reporter.nih.gov/search/QPpHrqO3ekG7Z4TLi-I3RA/project-details/10489966. Accessed Nov. 15, 2023. Biobank. National Institutes of Health. https://allofus.nih.gov/funding-and-program-partners/biobank. Accessed Nov. 15, 2023. 13th conference invited speakers. International Society for Applied Biological Sciences. https://isabs.hr/13th-conference-invited-speakers. Accessed Nov. 15, 2023. Founding members. Pharmacogenomics Global Research Network. https://pgrn.org/founders. Accessed Nov. 15, 2023. Members. Personalized Medicine Coalition. https://www.personalizedmedicinecoalition.org/membership/current-members. Accessed Nov. 15, 2023. Electronic Medical Records and Genomics (eMERGE) Network. National Human Genome Research Institute. https://www.genome.gov/Funded-Programs-Projects/Electronic-Medical-Records-and-Genomics-Network-eMERGE. Accessed Nov. 15, 2023. Member institutions. Alliance for Clinical Trials in Oncology. https://www.allianceforclinicaltrialsinoncology.org/main/public/standard.xhtml?path=%2FPublic%2FInstitutions. Accessed Nov. 15, 2023. Fowler GC, et al., eds. Pfenninger and Fowler's Procedures for Primary Care. 4th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed May 10, 2024. 相关 乳腺癌 绘制基因组信息 产品与服务 A Book: Beyond Breast Cancer 乳腺癌精准医疗关于医生与科室在 Mayo Clinic 治疗 Advertisement 妙佑医疗国际不为任何公司或产品背书。广告收入为我们的非营利使命提供支持。 广告与赞助政策 政策 机会 广告选择 妙佑医疗国际出版社 浏览妙佑医疗国际出版社提供的畅销书以及书籍和简报的特别优惠。 NEW: Listen to Health Matters Podcast - 妙佑医疗国际出版社NEW: Listen to Health Matters Podcast《妙佑医疗国际论失禁》(Mayo Clinic on Incontinence) - 妙佑医疗国际出版社《妙佑医疗国际论失禁》(Mayo Clinic on Incontinence)《糖尿病基本知识》 - 妙佑医疗国际出版社《糖尿病基本知识》妙佑医疗国际论平衡和听觉 - 妙佑医疗国际出版社妙佑医疗国际论平衡和听觉妙佑医疗国际免费饮食方案评估 - 妙佑医疗国际出版社妙佑医疗国际免费饮食方案评估妙佑医疗国际健康通讯 — 免费书籍 - 妙佑医疗国际出版社妙佑医疗国际健康通讯 — 免费书籍 PRC-20321688 患者护理和健康信息 医学检查与医疗程序 乳腺癌精准医疗