概述

多发性内分泌腺瘤病 1 型(MEN 1)有时也称为 Wermer 综合征,这种罕见的疾病会导致内分泌腺以及小肠和胃的某些部分出现肿瘤。在多发性内分泌腺瘤病 1 型中,内分泌腺(通常是副甲状腺、胰腺和垂体)会长出肿瘤,并释放可能引起疾病的过量激素。但是,这些肿瘤通常是非癌性(良性)的。

过量的激素可能引起各种体征和症状,其中包括疲劳、骨痛、骨折、肾结石以及胃或肠溃疡。MEN 1 尚无治愈方法,但定期接受检测可以发现问题,医生可以根据需要提供治疗。

MEN 1 是一种遗传性疾病,这意味着出现基因突变的人可能将这种疾病遗传给他们的子女。每个子女都有 50% 的几率遗传这种疾病。

症状

MEN 1 的体征和症状包括:

  • 疲倦
  • 骨痛
  • 骨折
  • 肾结石
  • 胃溃疡或肠溃疡

导致这些症状的原因是体内激素分泌过多。

在 Mayo Clinic 治疗

Aug. 31, 2022
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