Request an appointment By Mayo Clinic Staff Print Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need. U.S. patients Online requests Request an appointment at Mayo Clinic Mayo Clinic's campus in Jacksonville, Florida Central Appointment Office 904-953-0853 8 a.m. to 5 p.m. Eastern time Monday through Friday Mayo Clinic's campus in Rochester, Minnesota Central Appointment Office 507-538-3270 7 a.m. to 6 p.m. Central time Monday through Friday International patients International patients can request an appointment at any Mayo Clinic location. Appointment requests for international patients PRC-20394443 Patient Care & Health Information Tests & Procedures Intraoperative magnetic resonance imaging (iMRI)