Drug information provided by: IBM Micromedex
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Zoledronic acid injection is not indicated for use in children.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of zoledronic acid injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution in patients receiving zoledronic acid injection.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Bleeding problems or
Cancer, history of or
Dental or tooth problems or
Dental procedures or
Poor oral hygiene, or
Surgery (eg, dental surgery)—May increase risk for severe jaw problems.
Asthma, aspirin-sensitive or
Heart disease or
Kidney disease or
Mineral imbalance (eg, high or low calcium, magnesium, phosphorus, or potassium in the blood)—Use with caution. May make these conditions worse.
Bowel resection or
Parathyroid disease (eg, hypoparathyroidism) or
Parathyroid surgery or
Stomach absorption problems or
Thyroid surgery—These conditions may increase your risk of having hypocalcemia (low levels of calcium in the blood).
Dehydration (not enough water or fluid in your body)—May increase risk of severe kidney problems.
Hypocalcemia (low calcium in the blood) or
Kidney disease, severe (eg, kidney failure)—Should not be used in patients with these conditions.
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