Proper Use

Drug information provided by: Merative, Micromedex®

A nurse or other trained health professional will give you this medicine. It is given as a shot under your skin, usually in the arms, stomach, or thighs. You or your caregiver may also be trained to prepare and inject this medicine at home. Be sure that you understand how to use the medicine.

Before using this medicine, your doctor may want you to have certain blood tests and imaging procedures (eg, colonoscopy) done within 6 months before and 6 months or 1 year after of treatment.

This medicine should come with a Medication Guide and patient instructions. Read and follow the instructions carefully. Ask your doctor or pharmacist if you have any questions.

If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections. Do not inject into skin areas that are tender, bruised, red, or hard.

To use this medicine:

  • Inject the water provided in the prefilled syringe into the vial containing the powder.
  • Allow the vial to stand for about 30 seconds and then gently roll it between your palms for at least 15 seconds. Do not shake.
  • Allow the mixture to stand for about 2 minutes.
  • Check the vial for any undissolved powder. Gently roll the vial again until all the powder is dissolved. Do not shake. If the product remains undissolved after the second attempt, do not use it.
  • Use the mixture within 3 hours.
  • You might not use all of the medicine in the vial. Use each vial only one time. Do not save an open vial.
  • Use a new needle and syringe each time you inject your medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (solution):
    • For short bowel syndrome:
      • Adults and children 1 year of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 0.05 milligram (mg) per kilogram (kg) of body weight injected under the skin once a day.
      • Children younger than 1 year of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not shake, freeze, or store the mixed solution. Use it within 3 hours. Throw away any unused medicine after 3 hours.

Throw away used needles in a hard, closed container where the needles cannot poke through. Keep this container away from children and pets.

Portions of this document last updated: Feb. 01, 2024

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