Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Absent, missed, or irregular menstrual periods
  2. bladder pain
  3. blindness
  4. bloating or swelling of the face, arms, hands, lower legs, or feet
  5. bloody or cloudy urine
  6. blurred vision
  7. chills
  8. confusion
  9. cough
  10. decrease in the amount of urine
  11. decrease in height
  12. decreased vision
  13. difficult or labored breathing
  14. difficult, burning, or painful urination
  15. dizziness
  16. fainting
  17. fast heartbeat
  18. fever
  19. frequent urge to urinate
  20. heavy non-menstrual vaginal bleeding
  21. hoarseness
  22. increased clear or white vaginal discharge
  23. lower back or side pain
  24. noisy, rattling breathing
  25. pain in the back, ribs, arms, or legs
  26. painful or difficult urination
  27. pale skin
  28. rapid weight gain
  29. rapid, shallow breathing
  30. stopping of menstrual bleeding
  31. tightness in the chest
  32. tingling of the hands or feet
  33. troubled breathing at rest
  34. troubled breathing with exertion
  35. unusual bleeding or bruising
  36. unusual tiredness or weakness
  37. unusual weight gain or loss

Less common

  1. Abnormal growth filled with fluid or semisolid material
  2. black, tarry stools
  3. bleeding gums
  4. bloating
  5. blurred vision
  6. breast pain, redness, or swelling
  7. chest pain
  8. clear or bloody discharge from the nipple
  9. cough producing mucus
  10. dimpling of the breast skin
  11. feeling of warmth or heat
  12. flushing or redness of the skin, especially on the face and neck headache
  13. inverted nipple
  14. joint pain or stiffness
  15. large amount of cholesterol in the blood
  16. lump in the breast or under the arm
  17. nervousness
  18. persistent crusting or scaling of the nipple
  19. pinpoint red spots on the skin
  20. pounding in the ears
  21. skin rash or itching over the entire body
  22. slow heartbeat
  23. sore on the skin of the breast that does not heal
  24. stomach or pelvic discomfort, aching, or heaviness

Rare

  1. Anxiety
  2. bluish color of the skin
  3. tenderness

Incidence not known

  1. Blistering, peeling, loosening of the skin
  2. constipation
  3. dark urine
  4. diarrhea
  5. general feeling of discomfort or illness
  6. indigestion
  7. muscle pain
  8. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  9. loss of appetite
  10. nausea
  11. pains in the stomach, side, or abdomen, possibly radiating to the back
  12. red skin lesions, often with a purple center
  13. red, irritated eyes
  14. sore throat
  15. sores, ulcers, or white spots in the mouth or on the lips
  16. thickening of bronchial secretions
  17. vomiting
  18. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Back pain
  2. belching
  3. body aches or pain
  4. bone pain
  5. congestion
  6. depression
  7. difficulty in moving
  8. dryness of the throat
  9. hair loss or thinning of hair
  10. heartburn
  11. joint swelling
  12. lack or loss of strength
  13. mood changes
  14. muscle cramps or stiffness
  15. passing of gas
  16. redness of the face, neck, arms, and occasionally, upper chest
  17. runny nose
  18. shivering
  19. skin changes
  20. stomach upset, fullness, or pain
  21. sudden sweating
  22. tender, swollen glands in the neck
  23. trouble in swallowing
  24. trouble sleeping
  25. voice changes

Less common

  1. Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  2. itching of the vagina or genital area
  3. pain during sexual intercourse

Incidence not known

  1. Decreased interest in sexual intercourse
  2. inability to have or keep an erection
  3. loss in sexual ability, desire, drive, or performance

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Feb. 01, 2020

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