Proper Use

Drug information provided by: IBM Micromedex

Each dose of sulfapyridine should be taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (e.g., kidney stones) of the sulfa medicine.

For patients taking sulfapyridine for dermatitis herpetiformis:

  • Your doctor may want you to follow a strict, gluten-free diet.
  • You may have to use this medicine regularly for 6 months to a year before you can reduce the dose of sulfapyridine or stop it altogether. If you have any questions about this, check with your doctor.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For dermatitis herpetiformis:
    • Adults and adolescents: 250 milligrams to 1 gram four times a day until improvement occurs. After improvement has occurred, the dose should then be reduced by 250 to 500 milligrams every three days until there are no symptoms; that dose should be taken once daily.
    • Children: Use is not recommended, because children usually do not get this condition.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If your symptoms do return or get worse, take the missed dose as soon as possible. Then go back to your regular dosing schedule.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.