Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Bleeding gums
  2. bloating or swelling of the face, arms, hands, ankles, lower legs, or feet
  3. burning, numbness, pain, or tingling in all fingers except the smallest finger
  4. coughing up blood
  5. difficulty with breathing or swallowing
  6. difficulty with moving
  7. dizziness
  8. increased menstrual flow or vaginal bleeding
  9. muscle pain or stiffness
  10. nosebleeds
  11. not able to move
  12. pain, swelling, or redness in the joints
  13. prolonged bleeding from cuts
  14. rapid weight gain
  15. red or black, tarry stools
  16. red or dark brown urine
  17. tingling of the hands or feet
  18. unusual weight gain or loss

Rare

  1. Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  2. blurred vision
  3. bone pain
  4. change in personality
  5. change in the ability to see colors, especially blue or yellow
  6. changes in vision
  7. chills
  8. confusion
  9. constipation
  10. curved spine
  11. darkened urine
  12. dry mouth
  13. fast heartbeat
  14. fever
  15. flushed, dry skin
  16. fracture
  17. fruit-like breath odor
  18. headache
  19. increased hunger
  20. increased thirst
  21. increased urination
  22. indigestion
  23. limp pain in the hip or knee
  24. loss of appetite
  25. loss of consciousness
  26. nausea
  27. pains in the stomach, side, or abdomen, possibly radiating to the back
  28. problems with walking or talking
  29. seizures
  30. stomachache
  31. sweating
  32. tumor
  33. unusual tiredness or weakness
  34. vomiting
  35. yellow eyes or skin

Incidence not known

  1. Cough
  2. hives, itching, skin rash
  3. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  4. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  5. skin lesions
  6. tightness in the chest
  7. unexplained weight loss

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Backache
  2. excessive sweating
  3. extreme weakness
  4. increase in hand and foot size
  5. increased volume of pale, diluted urine
  6. pain in the arms or legs
  7. stop in menstruation

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Large, flat, blue, or purplish patches in the skin
  2. unusually warm skin

Rare

  1. Swelling of the breasts or breast soreness in both females and males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Feb. 01, 2023